Familial dysautonomia model reveals Ikbkap deletion causes apoptosis of Pax3+ progenitors and peripheral neurons

A coordinated codon-dependent regulation of translation by Elongator

(2012) Fanelie Bauer et al.   CELL CYCLE

IKAP expression levels modulate disease severity in a mouse model of familial dysautonomia

(2012) Paula Dietrich et al.   HUMAN MOLECULAR GENETICS

Mechanisms of disease in hereditary sensory and autonomic neuropathies

(2012) Annelies Rotthier et al.   Nature Reviews Neurology

IKAP/Elp1 Is Required In Vivo for Neurogenesis and Neuronal Survival, but Not for Neural Crest Migration

(2012) Barbara J. Hunnicutt et al.   PLoS One

Translational Control of Cell Division by Elongator

(2012) Fanelie Bauer et al.   Cell Reports

Can loss of muscle spindle afferents explain the ataxic gait in Riley-Day syndrome?

(2011) V. G. Macefield et al.   BRAIN

The Functional Organization of Cutaneous Low-Threshold Mechanosensory Neurons

(2011) Lishi Li et al.   CELL

IKAP/Elp1 involvement in cytoskeleton regulation and implication for familial dysautonomia

(2011) D. Cheishvili et al.   HUMAN MOLECULAR GENETICS

Pax3 Stimulates p53 Ubiquitination and Degradation Independent of Transcription

(2011) Xiao Dan Wang et al.   PLoS One

Deletion of Exon 20 of the Familial Dysautonomia Gene Ikbkap in Mice Causes Developmental Delay, Cardiovascular Defects, and Early Embryonic Lethality

(2011) Paula Dietrich et al.   PLoS One

MEC-17 is an α-tubulin acetyltransferase

(2010) Jyothi S. Akella et al.   NATURE

VGLUT2-Dependent Sensory Neurons in the TRPV1 Population Regulate Pain and Itch

(2010) Malin C. Lagerström et al.   NEURON

The major  -tubulin K40 acetyltransferase  TAT1 promotes rapid ciliogenesis and efficient mechanosensation

(2010) T. Shida et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Loss-of-function of IKAP/ELP1

(2010) Tiina Naumanen et al.   Cell Adhesion & Migration

The Caenorhabditis elegans Elongator Complex Regulates Neuronal α-tubulin Acetylation

(2010) Jachen A. Solinger et al.   PLoS Genetics

Elongator Controls the Migration and Differentiation of Cortical Neurons through Acetylation of α-Tubulin

(2009) Catherine Creppe et al.   CELL

Patterned assembly and neurogenesis in the chick dorsal root ganglion

(2009) Lynn George et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Acetylation Is Indispensable for p53 Activation

(2008) Yi Tang et al.   CELL

Dynamic regulation of the expression of neurotrophin receptors by Runx3

(2008) S. Nakamura et al.   DEVELOPMENT

Key basic helix–loop–helix transcription factor genes Hes1 and Ngn2 are regulated by Pax3 during mouse embryonic development

(2008) Hiromichi Nakazaki et al.   DEVELOPMENTAL BIOLOGY

IKAP localizes to membrane ruffles with filamin A and regulates actin cytoskeleton organization and cell migration

(2008) L. D. Johansen et al.   JOURNAL OF CELL SCIENCE

Cardiac outflow tract septation failure in Pax3-deficient embryos is due to p53-dependent regulation of migrating cardiac neural crest

(2008) Sarah C. Morgan et al.   MECHANISMS OF DEVELOPMENT

Loss of Mouse Ikbkap, a Subunit of Elongator, Leads to Transcriptional Deficits and Embryonic Lethality That Can Be Rescued by Human IKBKAP

(2008) Y.-T. Chen et al.   MOLECULAR AND CELLULAR BIOLOGY

The Groucho/TLE/Grg family of transcriptional co-repressors

(2008) Barbara H Jennings et al.   GENOME BIOLOGY