Mammalian Exo1 encodes both structural and catalytic functions that play distinct roles in essential biological processes

Mechanism of DNA resection during intrachromosomal recombination and immunoglobulin class switching

(2012) Anne Bothmer et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Visualization of Eukaryotic DNA Mismatch Repair Reveals Distinct Recognition and Repair Intermediates

(2011) Hans Hombauer et al.   CELL

Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family

(2011) Jillian Orans et al.   CELL

BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair

(2011) A. V. Nimonkar et al.   GENES & DEVELOPMENT

Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1

(2011) Valerie Garcia et al.   NATURE

Deficiency of FANCD2-Associated Nuclease KIAA1018/FAN1 Sensitizes Cells to Interstrand Crosslinking Agents

(2010) Katja Kratz et al.   CELL

Separable roles for Exonuclease I in meiotic DNA double-strand break repair

(2010) Rebecca E. Keelagher et al.   DNA REPAIR

Probing DNA- and ATP-mediated Conformational Changes in the MutS Family of Mispair Recognition Proteins Using Deuterium Exchange Mass Spectrometry

(2010) Marc L. Mendillo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Genetic Screen Identifies FAN1, a Fanconi Anemia-Associated Nuclease Necessary for DNA Interstrand Crosslink Repair

(2010) Agata Smogorzewska et al.   MOLECULAR CELL

Temporally and Biochemically Distinct Activities of Exo1 during Meiosis: Double-Strand Break Resection and Resolution of Double Holliday Junctions

(2010) Kseniya Zakharyevich et al.   MOLECULAR CELL

CtIP promotes microhomology-mediated alternative end joining during class-switch recombination

(2010) Mieun Lee-Theilen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Distinct Activities of Exonuclease 1 and Flap Endonuclease 1 at Telomeric G4 DNA

(2010) Aarthy C. Vallur et al.   PLoS One

MSH2/MSH6 Complex Promotes Error-Free Repair of AID-Induced dU:G Mispairs as well as Error-Prone Hypermutation of A:T Sites

(2010) Sergio Roa et al.   PLoS One

PMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance

(2010) J. M. M. van Oers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms of double-strand break repair in somatic mammalian cells

(2009) Andrea J. Hartlerode et al.   BIOCHEMICAL JOURNAL

Comprehensive Molecular Analysis of Mismatch Repair Gene Defects in Suspected Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer) Cases

(2009) J. Mueller et al.   CANCER RESEARCH

DNA end resection: Many nucleases make light work

(2009) Eleni P. Mimitou et al.   DNA REPAIR

Mouse Models of Colon Cancer

(2009) Makoto Mark Taketo et al.   GASTROENTEROLOGY

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

A possible mechanism for exonuclease 1-independent eukaryotic mismatch repair

(2009) F. A. Kadyrov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural and Functional Relationships of the XPF/MUS81 Family of Proteins

(2008) Alberto Ciccia et al.   Annual Review of Biochemistry

The Biochemistry of Somatic Hypermutation

(2008) Jonathan U. Peled et al.   Annual Review of Immunology

Sgs1 Helicase and Two Nucleases Dna2 and Exo1 Resect DNA Double-Strand Break Ends

(2008) Zhu Zhu et al.   CELL

DNA helicases Sgs1 and BLM promote DNA double-strand break resection

(2008) S. Gravel et al.   GENES & DEVELOPMENT

A Mutation in the Putative MLH3 Endonuclease Domain Confers a Defect in Both Mismatch Repair and Meiosis in Saccharomyces cerevisiae

(2008) K. T. Nishant et al.   GENETICS

Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing

(2008) Eleni P. Mimitou et al.   NATURE

Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair

(2008) A. V. Nimonkar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparative Analysis of Meiotic Progression in Female Mice Bearing Mutations in Genes of the DNA Mismatch Repair Pathway1

(2007) Rui Kan et al.   BIOLOGY OF REPRODUCTION