ABHD12 controls brain lysophosphatidylserine pathways that are deregulated in a murine model of the neurodegenerative disease PHARC

Targeted next-generation sequencing identifies a homozygous nonsense mutation in ABHD12, the gene underlying PHARC, in a family clinically diagnosed with Usher syndrome type 3

(2012) Tobias Eisenberger et al.   Orphanet Journal of Rare Diseases

Lipidomics at the Interface of Structure and Function in Systems Biology

(2011) Richard W. Gross et al.   CHEMISTRY & BIOLOGY

Neuroprotective agents: Cannabinoids

(2011) A.J. Sánchez et al.   CLINICAL IMMUNOLOGY

Signaling via Macrophage G2A Enhances Efferocytosis of Dying Neutrophils by Augmentation of Rac Activity

(2011) S. Courtney Frasch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of Microglial Phagocytosis Is Sufficient To Prevent Inflammatory Neuronal Death

(2011) J. J. Neher et al.   JOURNAL OF IMMUNOLOGY

Metabolomics annotates ABHD3 as a physiologic regulator of medium-chain phospholipids

(2011) Jonathan Z Long et al.   Nature Chemical Biology

Endocannabinoid Hydrolysis Generates Brain Prostaglandins That Promote Neuroinflammation

(2011) D. K. Nomura et al.   SCIENCE

Mutations in ABHD12 Cause the Neurodegenerative Disease PHARC: An Inborn Error of Endocannabinoid Metabolism

(2010) Torunn Fiskerstrand et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Activity-based Proteomics of Enzyme Superfamilies: Serine Hydrolases as a Case Study

(2010) Gabriel M. Simon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system

(2010) Joel E Schlosburg et al.   NATURE NEUROSCIENCE

Emerging lysophospholipid mediators, lysophosphatidylserine, lysophosphatidylthreonine, lysophosphatidylethanolamine and lysophosphatidylglycerol

(2009) Kumiko Makide et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Lysophosphatidylserine stimulates chemotactic migration in U87 human glioma cells

(2008) Sun Young Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Toll-like receptors in neurodegeneration

(2008) Eitan Okun et al.   BRAIN RESEARCH REVIEWS

NADPH Oxidase-dependent Generation of Lysophosphatidylserine Enhances Clearance of Activated and Dying Neutrophils via G2A

(2008) S. Courtney Frasch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuroaxonal Dystrophy Caused by Group VIA Phospholipase A2 Deficiency in Mice: A Model of Human Neurodegenerative Disease

(2008) K. Shinzawa et al.   JOURNAL OF NEUROSCIENCE

A novel Refsum-like disorder that maps to chromosome 20

(2008) T. Fiskerstrand et al.   NEUROLOGY