Engineering robust control of two-component system phosphotransfer using modular scaffolds

A tunable zinc finger-based framework for Boolean logic computation in mammalian cells

(2012) Jason J. Lohmueller et al.   NUCLEIC ACIDS RESEARCH

Organization of Intracellular Reactions with Rationally Designed RNA Assemblies

(2011) C. J. Delebecque et al.   SCIENCE

Structural Insights into Rcs Phosphotransfer: The Newly Identified RcsD-ABL Domain Enhances Interaction with the Response Regulator RcsB

(2011) Kerstin Schmöe et al.   STRUCTURE

Two-component signaling circuit structure and properties

(2010) Mark Goulian   CURRENT OPINION IN MICROBIOLOGY

Construction of a Genetic Multiplexer to Toggle between Chemosensory Pathways in Escherichia coli

(2010) Tae Seok Moon et al.   JOURNAL OF MOLECULAR BIOLOGY

A Synthetic Coiled-Coil Interactome Provides Heterospecific Modules for Molecular Engineering

(2010) Aaron W. Reinke et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Evolving a robust signal transduction pathway from weak cross-talk

(2010) Albert Siryaporn et al.   Molecular Systems Biology

Robust multicellular computing using genetically encoded NOR gates and chemical ‘wires’

(2010) Alvin Tamsir et al.   NATURE

Building blocks for protein interaction devices

(2010) Raik Grünberg et al.   NUCLEIC ACIDS RESEARCH

Rapid Diversification of Cell Signaling Phenotypes by Modular Domain Recombination

(2010) S. G. Peisajovich et al.   SCIENCE

Systematic Dissection and Trajectory-Scanning Mutagenesis of the Molecular Interface That Ensures Specificity of Two-Component Signaling Pathways

(2010) Emily J. Capra et al.   PLoS Genetics

BglBricks: A flexible standard for biological part assembly

(2010) J Christopher Anderson et al.   Journal of Biological Engineering

Structural Insight into Partner Specificity and Phosphoryl Transfer in Two-Component Signal Transduction

(2009) Patricia Casino et al.   CELL

Kinetic Buffering of Cross Talk between Bacterial Two-Component Sensors

(2009) Eli S. Groban et al.   JOURNAL OF MOLECULAR BIOLOGY

Quantitative effect of scaffold abundance on signal propagation

(2009) Stephen A Chapman et al.   Molecular Systems Biology

A dimerization-dependent mechanism drives RAF catalytic activation

(2009) Thanashan Rajakulendran et al.   NATURE

Synthetic protein scaffolds provide modular control over metabolic flux

(2009) John E Dueber et al.   NATURE BIOTECHNOLOGY

Synthetic Gene Networks That Count

(2009) A. E. Friedland et al.   SCIENCE

Rewiring the Specificity of Two-Component Signal Transduction Systems

(2008) Jeffrey M. Skerker et al.   CELL

Toward scalable parts families for predictable design of biological circuits

(2008) Julius B Lucks et al.   CURRENT OPINION IN MICROBIOLOGY

Cross-talk suppression between the CpxA-CpxR and EnvZ-OmpR two-component systems inE. coli

(2008) Albert Siryaporn et al.   MOLECULAR MICROBIOLOGY

A fast, robust and tunable synthetic gene oscillator

(2008) Jesse Stricker et al.   NATURE

Using Engineered Scaffold Interactions to Reshape MAP Kinase Pathway Signaling Dynamics

(2008) C. J. Bashor et al.   SCIENCE