The protein kinase Akt1 regulates the interferon response through phosphorylation of the transcriptional repressor EMSY

Dual Regulatory Roles of Phosphatidylinositol 3-Kinase in IFN Signaling

(2014) S. Kaur et al.   JOURNAL OF IMMUNOLOGY

Akt2 Regulates All Akt Isoforms and Promotes Resistance to Hypoxia through Induction of miR-21 upon Oxygen Deprivation

(2011) C. Polytarchou et al.   CANCER RESEARCH

First-in-Man Clinical Trial of the Oral Pan-AKT Inhibitor MK-2206 in Patients With Advanced Solid Tumors

(2011) Timothy A. Yap et al.   JOURNAL OF CLINICAL ONCOLOGY

Interferon-Stimulated Genes and Their Protein Products: What and How?

(2011) Ernest C. Borden et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Mechanism of Inhibition of Retrovirus Release from Cells by Interferon-Induced Gene ISG15

(2011) Z. Kuang et al.   JOURNAL OF VIROLOGY

EMSY overexpression disrupts the BRCA2/RAD51 pathway in the DNA-damage response: implications for chromosomal instability/recombination syndromes as checkpoint diseases

(2011) Isabelle Cousineau et al.   MOLECULAR GENETICS AND GENOMICS

Development of an oncolytic herpes simplex virus using a tumor-specific HIF-responsive promoter

(2010) S L Longo et al.   CANCER GENE THERAPY

Oncolysis of Prostate Cancers Induced by Vesicular Stomatitis Virus in PTEN Knockout Mice

(2010) M. Moussavi et al.   CANCER RESEARCH

Knockdown of interferon-induced transmembrane protein 1 (IFITM1) inhibits proliferation, migration, and invasion of glioma cells

(2010) Fang Yu et al.   JOURNAL OF NEURO-ONCOLOGY

The Interferon-Induced Gene ISG15 Blocks Retrovirus Release from Cells Late in the Budding Process

(2010) A. Pincetic et al.   JOURNAL OF VIROLOGY

The Actin-Bundling Protein Palladin Is an Akt1-Specific Substrate that Regulates Breast Cancer Cell Migration

(2010) Y. Rebecca Chin et al.   MOLECULAR CELL

Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction

(2009) Daming Gao et al.   NATURE CELL BIOLOGY

MicroRNAs Differentially Regulated by Akt Isoforms Control EMT and Stem Cell Renewal in Cancer Cells

(2009) D. Iliopoulos et al.   Science Signaling

IFN-Induced Transmembrane Protein 1 Promotes Invasion at Early Stage of Head and Neck Cancer Progression

(2008) H. Hatano et al.   CLINICAL CANCER RESEARCH

ISG15 as a novel tumor biomarker for drug sensitivity

(2008) Shyamal D. Desai et al.   MOLECULAR CANCER THERAPEUTICS

An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer

(2008) R. R. Weichselbaum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of the Akt pathway in mRNA translation of interferon-stimulated genes

(2008) S. Kaur et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA