Mammalian ribonucleotide reductase subunit p53R2 is required for mitochondrial DNA replication and DNA repair in quiescent cells

Deoxyribonucleotide Metabolism in Cycling and Resting Human Fibroblasts with a Missense Mutation in p53R2, a Subunit of Ribonucleotide Reductase

(2011) Giovanna Pontarin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

γH2Ax: Biomarker of Damage or Functional Participant in DNA Repair “All that Glitters Is not Gold!”

(2011) James E. Cleaver   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Mechanisms of dNTP supply that play an essential role in maintaining genome integrity in eukaryotic cells

(2010) Hiroyuki Niida et al.   CANCER SCIENCE

Regulation by degradation, a cellular defense against deoxyribonucleotide pool imbalances

(2010) Chiara Rampazzo et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Mechanisms of mutagenesis in vivo due to imbalanced dNTP pools

(2010) D. Kumar et al.   NUCLEIC ACIDS RESEARCH

Ribonucleotide Reductase Inhibition Enhances Chemoradiosensitivity of Human Cervical Cancers

(2010) Charles A. Kunos et al.   RADIATION RESEARCH

A Heterozygous Truncating Mutation in RRM2B Causes Autosomal-Dominant Progressive External Ophthalmoplegia with Multiple mtDNA Deletions

(2009) Henna Tyynismaa et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Mitochondrial Neurogastrointestinal Encephalopathy Due to Mutations in RRM2B

(2009) Aziz Shaibani et al.   ARCHIVES OF NEUROLOGY

Immortalized Skin Fibroblasts Expressing Conditional MyoD as a Renewable and Reliable Source of Converted Human Muscle Cells to Assess Therapeutic Strategies for Muscular Dystrophies: Validation of an Exon-Skipping Approach to Restore Dystrophin in Duchenne Muscular Dystrophy Cells

(2009) Soraya Chaouch et al.   HUMAN GENE THERAPY

Clinical and molecular features of mitochondrial DNA depletion syndromes

(2009) A. Spinazzola et al.   JOURNAL OF INHERITED METABOLIC DISEASE

A novel mutation of the RRM2B gene in an infant with early fatal encephalomyopathy, central hypomyelination, and tubulopathy

(2009) Birgit Acham-Roschitz et al.   MOLECULAR GENETICS AND METABOLISM

A novel homozygous RRM2B missense mutation in association with severe mtDNA depletion

(2009) Gittan Kollberg et al.   NEUROMUSCULAR DISORDERS

Impairment of the DNA Repair and Growth Arrest Pathways by p53R2 Silencing Enhances DNA Damage-Induced Apoptosis in a p53-Dependent Manner in Prostate Cancer Cells

(2008) H.-L. Devlin et al.   MOLECULAR CANCER RESEARCH

Mitochondrial DNA depletion syndrome due to mutations in the RRM2B gene

(2008) Belén Bornstein et al.   NEUROMUSCULAR DISORDERS

Ribonucleotide reduction is a cytosolic process in mammalian cells independently of DNA damage

(2008) G. Pontarin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA