The activity of Gli transcription factors is essential for Kras-induced pancreatic tumorigenesis
Published 2012 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The activity of Gli transcription factors is essential for Kras-induced pancreatic tumorigenesis
Authors
Keywords
-
Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 109, Issue 17, Pages E1038-E1047
Publisher
Proceedings of the National Academy of Sciences
Online
2012-04-10
DOI
10.1073/pnas.1114168109
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- IκB Kinase ɛ Expression in Pancreatic Ductal Adenocarcinoma
- (2011) Anna Cheng et al. AMERICAN JOURNAL OF CLINICAL PATHOLOGY
- Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladder
- (2011) Kunyoo Shin et al. NATURE
- miR-301a as an NF-κB activator in pancreatic cancer cells
- (2010) Zhongxin Lu et al. EMBO JOURNAL
- Clinical Experience With Hedgehog Pathway Inhibitors
- (2010) Jennifer A. Low et al. JOURNAL OF CLINICAL ONCOLOGY
- The landscape of somatic copy-number alteration across human cancers
- (2010) Rameen Beroukhim et al. NATURE
- DYRK1B-dependent autocrine-to-paracrine shift of Hedgehog signaling by mutant RAS
- (2010) Matthias Lauth et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Emerging roles for the non-canonical IKKs in cancer
- (2010) R R Shen et al. ONCOGENE
- Primary cilia regulate Gli/Hedgehog activation in pancreas
- (2010) S. Cervantes et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hedgehog pathway-regulated gene networks in cerebellum development and tumorigenesis
- (2010) E. Y. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Learning from Jekyll to control Hyde: Hedgehog signaling in development and cancer
- (2010) Monique T. Barakat et al. TRENDS IN MOLECULAR MEDICINE
- Context-dependent Regulation of the GLI Code in Cancer by HEDGEHOG and Non-HEDGEHOG Signals
- (2010) B. Stecca et al. Journal of Molecular Cell Biology
- Gli2 and p53 Cooperate to Regulate IGFBP-3- Mediated Chondrocyte Apoptosis in the Progression from Benign to Malignant Cartilage Tumors
- (2009) Louisa Ho et al. CANCER CELL
- Pancreatic Cancer and Precursor Pancreatic Intraepithelial Neoplasia Lesions Are Devoid of Primary Cilia
- (2009) E. S. Seeley et al. CANCER RESEARCH
- Hedgehog activation is required upstream of Wnt signalling to control neural progenitor proliferation
- (2009) R. Alvarez-Medina et al. DEVELOPMENT
- A GLI1-p53 inhibitory loop controls neural stem cell and tumour cell numbers
- (2009) Barbara Stecca et al. EMBO JOURNAL
- GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation
- (2009) O. Nolan-Stevaux et al. GENES & DEVELOPMENT
- Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1
- (2009) David A. Barbie et al. NATURE
- Requirement for NF-κB signalling in a mouse model of lung adenocarcinoma
- (2009) Etienne Meylan et al. NATURE
- The Role of Nuclear Factor κB in Pancreatic Cancer and the Clinical Applications of Targeted Therapy
- (2009) Bryan Holcomb et al. PANCREAS
- Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade
- (2009) J. M. Hyman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer
- (2009) J. P. Morton et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis
- (2009) H. Tian et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Deletion of Atoh1 Disrupts Sonic Hedgehog Signaling in the Developing Cerebellum and Prevents Medulloblastoma
- (2009) A. Flora et al. SCIENCE
- Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer
- (2009) K. P. Olive et al. SCIENCE
- Sonic Hedgehog Promotes Desmoplasia in Pancreatic Cancer
- (2008) J. M. Bailey et al. CLINICAL CANCER RESEARCH
- A genome-scale analysis of the cis-regulatory circuitry underlying sonic hedgehog-mediated patterning of the mammalian limb
- (2008) S. A. Vokes et al. GENES & DEVELOPMENT
- A paracrine requirement for hedgehog signalling in cancer
- (2008) Robert L. Yauch et al. NATURE
- Pathological responses to oncogenic Hedgehog signaling in skin are dependent on canonical Wnt/β-catenin signaling
- (2008) Steven Hoseong Yang et al. NATURE GENETICS
- Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses
- (2008) S. Jones et al. SCIENCE
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started