Regulatory effects of mTORC2 complexes in type I IFN signaling and in the generation of IFN responses

Dual Regulatory Roles of Phosphatidylinositol 3-Kinase in IFN Signaling

(2014) S. Kaur et al.   JOURNAL OF IMMUNOLOGY

Activation of mTORC2 by Association with the Ribosome

(2011) Vittoria Zinzalla et al.   CELL

mTOR complex 2 signaling and functions

(2011) Won Jun Oh et al.   CELL CYCLE

Dual mTORC2/mTORC1 Targeting Results in Potent Suppressive Effects on Acute Myeloid Leukemia (AML) Progenitors

(2011) J. K. Altman et al.   CLINICAL CANCER RESEARCH

Emerging roles for mammalian target of rapamycin inhibitors in the treatment of solid tumors and hematological malignancies

(2011) Nushmia Z. Khokhar et al.   CURRENT OPINION IN ONCOLOGY

Evidence for Direct Activation of mTORC2 Kinase Activity by Phosphatidylinositol 3,4,5-Trisphosphate

(2011) Xiaoqing Gan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Akt and mRNA translation by interferons

(2010) Surinder Kaur et al.   CELL CYCLE

Mechanisms of mRNA translation of interferon stimulated genes

(2010) Sonali Joshi et al.   CYTOKINE

mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide

(2010) Won Jun Oh et al.   EMBO JOURNAL

Essential Role for Mnk Kinases in Type II Interferon (IFNγ) Signaling and Its Suppressive Effects on Normal Hematopoiesis

(2010) Sonali Joshi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Interferon Stimulated Gene 54 Promotes Apoptosis

(2010) Marcin Stawowczyk et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor

(2010) Matthew R Janes et al.   NATURE MEDICINE

mTOR: from growth signal integration to cancer, diabetes and ageing

(2010) Roberto Zoncu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Critical roles for mTORC2- and rapamycin-insensitive mTORC1-complexes in growth and survival of BCR-ABL-expressing leukemic cells

(2010) Nathalie Carayol et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

mTOR signaling at a glance

(2009) M. Laplante et al.   JOURNAL OF CELL SCIENCE

Interferon-Dependent Engagement of Eukaryotic Initiation Factor 4B via S6 Kinase (S6K)- and Ribosomal Protein S6K-Mediated Signals

(2009) B. Kroczynska et al.   MOLECULAR AND CELLULAR BIOLOGY

Type I interferon (IFN)-dependent activation of Mnk1 and its role in the generation of growth inhibitory responses

(2009) S. Joshi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C

(2008) Valeria Facchinetti et al.   EMBO JOURNAL

Role of the Akt pathway in mRNA translation of interferon-stimulated genes

(2008) S. Kaur et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA