Unique thrombin inhibition mechanism by anophelin, an anticoagulant from the malaria vector

Towards automated crystallographic structure refinement withphenix.refine

(2012) Pavel V. Afonine et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The Anopheles gambiae cE5, a tight- and fast-binding thrombin inhibitor with post-transcriptionally regulated salivary-restricted expression

(2012) Raffaele Ronca et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

ID29: a high-intensity highly automated ESRF beamline for macromolecular crystallography experiments exploiting anomalous scattering

(2012) Daniele de Sanctis et al.   JOURNAL OF SYNCHROTRON RADIATION

Rational Design and Characterization of D-Phe-Pro-D-Arg-Derived Direct Thrombin Inhibitors

(2012) Ana C. Figueiredo et al.   PLoS One

Structural basis of thrombin-mediated factor V activation: the Glu666-Glu672 sequence is critical for processing at the heavy chain-B domain junction

(2011) M. A. Corral-Rodriguez et al.   BLOOD

MEROPS: the database of proteolytic enzymes, their substrates and inhibitors

(2011) N. D. Rawlings et al.   NUCLEIC ACIDS RESEARCH

Crystal Structure of Thrombin in Complex with S-Variegin: Insights of a Novel Mechanism of Inhibition and Design of Tunable Thrombin Inhibitors

(2011) Cho Yeow Koh et al.   PLoS One

Integration, scaling, space-group assignment and post-refinement

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Crystallization and preliminary crystallographic characterization of three peptidic inhibitors in complex with α-thrombin

(2010) Ana Carvalho Figueiredo et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Transcriptomic and functional analysis of the Anopheles gambiae salivary gland in relation to blood feeding

(2010) Suchismita Das et al.   BMC GENOMICS

An insight into the sialome of blood-feeding Nematocera

(2010) José M.C. Ribeiro et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Crystal Structure of Thrombin Bound to the Uncleaved Extracellular Fragment of PAR1

(2010) Prafull S. Gandhi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Leech-Derived Thrombin Inhibitors: From Structures to Mechanisms to Clinical Applications

(2010) María Ángeles Corral-Rodríguez et al.   JOURNAL OF MEDICINAL CHEMISTRY

NMR resonance assignments of thrombin reveal the conformational and dynamic effects of ligation

(2010) B. C. Lechtenberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Drawing the PDB: Protein−Ligand Complexes in Two Dimensions

(2010) Katrin Stierand et al.   ACS Medicinal Chemistry Letters

ALINE: a WYSIWYG protein-sequence alignment editor for publication-quality alignments

(2009) Charles Simon Bond et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The salivary gland transcriptome of the neotropical malaria vector Anopheles darlingi reveals accelerated evolution of genes relevant to hematophagy

(2009) Eric Calvo et al.   BMC GENOMICS

Tick-derived Kunitz-type inhibitors as antihemostatic factors

(2009) María Ángeles Corral-Rodríguez et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Salivary gland transcriptome analysis during Plasmodium infection in malaria vector Anopheles stephensi

(2009) Rajnikant Dixit et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Calcium-bound structure of calpain and its mechanism of inhibition by calpastatin

(2008) Rachel A. Hanna et al.   NATURE

Concerted multi-pronged attack by calpastatin to occlude the catalytic cleft of heterodimeric calpains

(2008) Tudor Moldoveanu et al.   NATURE

Isolation, Cloning and Structural Characterisation of Boophilin, a Multifunctional Kunitz-Type Proteinase Inhibitor from the Cattle Tick

(2008) Sandra Macedo-Ribeiro et al.   PLoS One

Protein secondary structure analyses from circular dichroism spectroscopy: Methods and reference databases

(2007) Lee Whitmore et al.   BIOPOLYMERS