Structure of RPE65 isomerase in a lipidic matrix reveals roles for phospholipids and iron in catalysis

Aromatic Residues in the Substrate Cleft of RPE65 Protein Govern Retinol Isomerization and Modulate Its Progression

(2012) Preethi Chander et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Using SAD data inPhaser

(2011) Randy J. Read et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Binding to lipid membrane induces conformational changes in RPE65: implications for its isomerohydrolase activity

(2011) Olga Nikolaeva et al.   BIOCHEMICAL JOURNAL

HiLiDe—Systematic Approach to Membrane Protein Crystallization in Lipid and Detergent

(2011) Pontus Gourdon et al.   CRYSTAL GROWTH & DESIGN

Lipidic cubic phase technologies for membrane protein structural studies

(2011) Vadim Cherezov   CURRENT OPINION IN STRUCTURAL BIOLOGY

α-Phenyl-N-tert-butylnitrone (PBN) Prevents Light-induced Degeneration of the Retina by Inhibiting RPE65 Protein Isomerohydrolase Activity

(2011) Md Nawajes A. Mandal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of metarhodopsin II

(2011) Hui-Woog Choe et al.   NATURE

Experimental phasing withSHELXC/D/E: combining chain tracing with density modification

(2010) George M. Sheldrick   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Importance of Membrane Structural Integrity for RPE65 Retinoid Isomerization Activity

(2010) Marcin Golczak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane-binding and enzymatic properties of RPE65

(2010) Philip D. Kiser et al.   PROGRESS IN RETINAL AND EYE RESEARCH

The biochemical and structural basis for trans-to-cis isomerization of retinoids in the chemistry of vision

(2010) Johannes von Lintig et al.   TRENDS IN BIOCHEMICAL SCIENCES

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Electron Crystallography as a Technique to Study the Structure on Membrane Proteins in a Lipidic Environment

(2009) Stefan Raunser et al.   Annual Review of Biophysics

Purified RPE65 shows isomerohydrolase activity after reassociation with a phospholipid membrane

(2009) Olga Nikolaeva et al.   FEBS Journal

RPE65, Visual Cycle Retinol Isomerase, Is Not Inherently 11-cis-specific

(2009) T. Michael Redmond et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of native RPE65, the retinoid isomerase of the visual cycle

(2009) P. D. Kiser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA