Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms

Multiple Factors Confer Specific Cdc42 and Rac Protein Activation by Dedicator of Cytokinesis (DOCK) Nucleotide Exchange Factors

(2011) Kiran Kulkarni et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Evolutionarily Conserved Autoinhibitory Molecular Switch in ELMO Proteins Regulates Rac Signaling

(2010) Manishha Patel et al.   CURRENT BIOLOGY

Structural Basis of Membrane Targeting by the Dock180 Family of Rho Family Guanine Exchange Factors (Rho-GEFs)

(2010) Lakshmanane Premkumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective control of type I IFN induction by the Rac activator DOCK2 during TLR-mediated plasmacytoid dendritic cell activation

(2010) Kazuhito Gotoh et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Sequential Regulation of DOCK2 Dynamics by Two Phospholipids During Neutrophil Chemotaxis

(2009) A. Nishikimi et al.   SCIENCE

Activation of Rho GTPases by DOCK Exchange Factors Is Mediated by a Nucleotide Sensor

(2009) J. Yang et al.   SCIENCE

An α-Helical Extension of the ELMO1 Pleckstrin Homology Domain Mediates Direct Interaction to DOCK180 and Is Critical in Rac Signaling

(2008) David Komander et al.   MOLECULAR BIOLOGY OF THE CELL