DNA methylation as a dynamic regulator of development and disease processes: spotlight on the prostate

The epigenetics of prostate cancer diagnosis and prognosis

(2015) Michael L. Blute et al.   CURRENT OPINION IN UROLOGY

DNMT3L interacts with transcription factors to target DNMT3L/DNMT3B to specific DNA sequences: Role of the DNMT3L/DNMT3B/p65-NFκB complex in the (de-)methylation of TRAF1

(2014) Romain Pacaud et al.   BIOCHIMIE

Androgen receptor DNA methylation regulates the timing and androgen sensitivity of mouse prostate ductal development

(2014) Kimberly P. Keil et al.   DEVELOPMENTAL BIOLOGY

DNA methylation of E-cadherin is a priming mechanism for prostate development

(2014) Kimberly P. Keil et al.   DEVELOPMENTAL BIOLOGY

Essential Roles of Epithelial Bone Morphogenetic Protein Signaling During Prostatic Development

(2014) Akiko Omori et al.   ENDOCRINOLOGY

Prevalence of Inflammation and Benign Prostatic Hyperplasia on Autopsy in Asian and Caucasian Men

(2014) Alexandre R. Zlotta et al.   EUROPEAN UROLOGY

Personalized Medicine for the Management of Benign Prostatic Hyperplasia

(2014) Seth K. Bechis et al.   JOURNAL OF UROLOGY

Serotonin Regulates Calcium Homeostasis in Lactation by Epigenetic Activation of Hedgehog Signaling

(2014) Jimena Laporta et al.   MOLECULAR ENDOCRINOLOGY

Human Endometrial DNA Methylome Is Cycle-Dependent and Is Associated With Gene Expression Regulation

(2014) Sahar Houshdaran et al.   MOLECULAR ENDOCRINOLOGY

Epigenetic modifications in prostate cancer

(2014) Marjolaine Ngollo et al.   Epigenomics

The effects of perinatal testosterone exposure on the DNA methylome of the mouse brain are late-emerging

(2014) Negar M Ghahramani et al.   Biology of Sex Differences

Conditional knockdown of DNA methyltransferase 1 reveals a key role of retinal pigment epithelium integrity in photoreceptor outer segment morphogenesis

(2013) I. O. Nasonkin et al.   DEVELOPMENT

Beta-catenin (CTNNB1) induces Bmp expression in urogenital sinus epithelium and participates in prostatic bud initiation and patterning

(2013) Vatsal Mehta et al.   DEVELOPMENTAL BIOLOGY

Catalog of mRNA expression patterns for DNA methylating and demethylating genes in developing mouse lower urinary tract

(2013) Kimberly P. Keil et al.   GENE EXPRESSION PATTERNS

DNMT1 represses p53 to maintain progenitor cell survival during pancreatic organogenesis

(2013) S. Georgia et al.   GENES & DEVELOPMENT

High-resolution DNA methylome analysis of primordial germ cells identifies gender-specific reprogramming in mice

(2013) H. Kobayashi et al.   GENOME RESEARCH

Age-associated epigenetic drift: implications, and a case of epigenetic thrift?

(2013) A. E. Teschendorff et al.   HUMAN MOLECULAR GENETICS

Distinctive topology of age-associated epigenetic drift in the human interactome

(2013) J. West et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetic susceptibility factors for prostate cancer with aging

(2013) N. A. Damaschke et al.   PROSTATE

5-Methylcytosine DNA Demethylation: More Than Losing a Methyl Group

(2012) Don-Marc Franchini et al.   Annual Review of Genetics

Age-related changes in prostate zonal volumes as measured by high-resolution magnetic resonance imaging (MRI): a cross-sectional study in over 500 patients

(2012) Baris Turkbey et al.   BJU INTERNATIONAL

Tet family proteins and 5-hydroxymethylcytosine in development and disease

(2012) L. Tan et al.   DEVELOPMENT

Testosterone and 17β-Estradiol Induce Glandular Prostatic Growth, Bladder Outlet Obstruction, and Voiding Dysfunction in Male Mice

(2012) Tristan M. Nicholson et al.   ENDOCRINOLOGY

Wnt Inhibitory Factor 1 (Wif1) Is Regulated by Androgens and Enhances Androgen-Dependent Prostate Development

(2012) Kimberly P. Keil et al.   ENDOCRINOLOGY

Activation of innate anti-viral immune response genes in symptomatic benign prostatic hyperplasia

(2012) A A Madigan et al.   GENES AND IMMUNITY

Progressive Alopecia Reveals Decreasing Stem Cell Activation Probability during Aging of Mice with Epidermal Deletion of DNA Methyltransferase 1

(2012) Ji Li et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Stromal epigenetic dysregulation is sufficient to initiate mouse prostate cancer via paracrine Wnt signaling

(2012) Y. Zong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Developmental and androgenic regulation of chromatin regulators EZH2 and ANCCA/ATAD2 in the prostate Via MLL histone methylase complex

(2012) Zhijian Duan et al.   PROSTATE

In Vivo Control of CpG and Non-CpG DNA Methylation by DNA Methyltransferases

(2012) Julia Arand et al.   PLoS Genetics

Sex hormone control of left ventricular structure/function: mechanistic insights using echocardiography, expression, and DNA methylation analyses in adult mice

(2011) Igal A. Sebag et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Thymine DNA Glycosylase Is Essential for Active DNA Demethylation by Linked Deamination-Base Excision Repair

(2011) Salvatore Cortellino et al.   CELL

Specification of the germ cell lineage in mice: A process orchestrated by the PR-domain proteins, Blimp1 and Prdm14

(2011) Kazuki Kurimoto et al.   CELL CYCLE

Epigenetic reprogramming in mouse pre-implantation development and primordial germ cells

(2011) M. Saitou et al.   DEVELOPMENT

A historical perspective on the role of stroma in the pathogenesis of benign prostatic hyperplasia

(2011) Gerald R. Cunha et al.   DIFFERENTIATION

Neonatal Exposure to Estradiol/Bisphenol A Alters Promoter Methylation and Expression ofNsbp1andHpcal1Genes and Transcriptional Programs ofDnmt3a/bandMbd2/4in the RatProstate Gland Throughout Life

(2011) Wan-yee Tang et al.   ENDOCRINOLOGY

Deoxyribonucleic acid methyltransferases and methyl-CpG-binding domain proteins in human endometrium and endometriosis

(2011) Kim J.A.F. van Kaam et al.   FERTILITY AND STERILITY

Stroma Regulates Increased Epithelial Lateral Cell Adhesion in 3D Culture: A Role for Actin/Cadherin Dynamics

(2011) Karen F. Chambers et al.   PLoS One

Modulation of E-cadherin expression by K-Ras; involvement of DNA methyltransferase-3b

(2010) Osong Kwon et al.   CARCINOGENESIS

β-catenin Activity in the Dermal Papilla Regulates Morphogenesis and Regeneration of Hair

(2010) David Enshell-Seijffers et al.   DEVELOPMENTAL CELL

Expression and regulation of DNA methyltransferases in human endometrium

(2010) Zoë L. Vincent et al.   FERTILITY AND STERILITY

Epigenetic alterations in aging

(2010) Susana Gonzalo   JOURNAL OF APPLIED PHYSIOLOGY

Activation of the type I interferon pathway in primary Sjogren’s syndrome

(2010) Clio P. Mavragani et al.   JOURNAL OF AUTOIMMUNITY

Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency

(2010) Christian Popp et al.   NATURE

Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification

(2010) Shinsuke Ito et al.   NATURE

Rare histological patterns of prostatic ductal adenocarcinoma

(2010) Thomas K. Lee et al.   PATHOLOGY

Conservation and divergence of methylation patterning in plants and animals

(2010) S. Feng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bone Morphogenetic Protein Antagonist Noggin Promotes Skin Tumorigenesis via Stimulation of the Wnt and Shh Signaling Pathways

(2009) Andrey A. Sharov et al.   AMERICAN JOURNAL OF PATHOLOGY

Non-CpG Methylation of the PGC-1α Promoter through DNMT3B Controls Mitochondrial Density

(2009) Romain Barrès et al.   Cell Metabolism

DNA Methyltransferase 1 Is Essential for and Uniquely Regulates Hematopoietic Stem and Progenitor Cells

(2009) Jennifer J. Trowbridge et al.   Cell Stem Cell

DNA hypomethylation restricted to the murine forebrain induces cortical degeneration and impairs postnatal neuronal maturation

(2009) Leah K. Hutnick et al.   HUMAN MOLECULAR GENETICS

Histone methylation is mechanistically linked to DNA methylation at imprinting control regions in mammals

(2009) Amandine Henckel et al.   HUMAN MOLECULAR GENETICS

DNA methyltransferase expression in the human endometrium: down-regulation by progesterone and estrogen

(2009) Y. Yamagata et al.   HUMAN REPRODUCTION

Reprogramming towards pluripotency requires AID-dependent DNA demethylation

(2009) Nidhi Bhutani et al.   NATURE

Epigenetic dynamics of stem cells and cell lineage commitment: digging Waddington's canal

(2009) Myriam Hemberger et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE

Retinoic acid induces prostatic bud formation

(2008) Chad M. Vezina et al.   DEVELOPMENTAL DYNAMICS

Mesenchymal mechanisms in prostate organogenesis

(2008) Axel A. Thomson   DIFFERENTIATION

Estrogen-regulated development and differentiation of the prostate

(2008) Stephen J. McPherson et al.   DIFFERENTIATION

Prostate development: a historical perspective

(2008) Barry G. Timms   DIFFERENTIATION

Stage-Specific Alterations of DNA Methyltransferase Expression, DNA Hypermethylation, and DNA Hypomethylation during Prostate Cancer Progression in the Transgenic Adenocarcinoma of Mouse Prostate Model

(2008) S. R. Morey Kinney et al.   MOLECULAR CANCER RESEARCH

Epigenetic events in mammalian germ-cell development: reprogramming and beyond

(2008) Hiroyuki Sasaki et al.   NATURE REVIEWS GENETICS

The Relationship between Prostate Inflammation and Lower Urinary Tract Symptoms: Examination of Baseline Data from the REDUCE Trial

(2007) J. Curtis Nickel et al.   EUROPEAN UROLOGY