Autoinhibition and phosphorylation-induced activation mechanisms of human cancer and autoimmune disease-related E3 protein Cbl-b

Recognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complex

(2011) Matthew L Bentley et al.   EMBO JOURNAL

The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor

(2011) L. Zhang et al.   GENES & DEVELOPMENT

Phosphoinositide-incorporated lipid–protein nanodiscs: A tool for studying protein–lipid interactions

(2010) Yoshihiro Kobashigawa et al.   ANALYTICAL BIOCHEMISTRY

Cbl and Human Myeloid Neoplasms: The Cbl Oncogene Comes of Age: Figure 1.

(2010) Stephen C. Kales et al.   CANCER RESEARCH

Novel Oncogenic Mutations ofCBLin Human Acute Myeloid Leukemia That Activate Growth and Survival Pathways Depend on Increased Metabolism

(2010) Margret S. Fernandes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gain of CBL-interacting protein, a possible alternative to CBL mutations in myeloid malignancies

(2010) J Adélaïde et al.   LEUKEMIA

Germline CBL mutations cause developmental abnormalities and predispose to juvenile myelomonocytic leukemia

(2010) Charlotte M Niemeyer et al.   NATURE GENETICS

Variants within the immunoregulatory CBLB gene are associated with multiple sclerosis

(2010) Serena Sanna et al.   NATURE GENETICS

Attachment of an NMR-invisible solubility enhancement tag using a sortase-mediated protein ligation method

(2009) Yoshihiro Kobashigawa et al.   JOURNAL OF BIOMOLECULAR NMR

Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms

(2009) Masashi Sanada et al.   NATURE

E2 interaction and dimerization in the crystal structure of TRAF6

(2009) Qian Yin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Identification and functional analysis of CBLB mutations in type 1 diabetes

(2008) Norihide Yokoi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans

(2008) K Linke et al.   CELL DEATH AND DIFFERENTIATION

Structures of the cIAP2 RING Domain Reveal Conformational Changes Associated with Ubiquitin-conjugating Enzyme (E2) Recruitment

(2008) Peter D. Mace et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

E2–c-Cbl Recognition Is Necessary but not Sufficient for Ubiquitination Activity

(2008) Anding Huang et al.   JOURNAL OF MOLECULAR BIOLOGY