Dose-dependent alcohol-induced alterations in chromatin structure persist beyond the window of exposure and correlate with fetal alcohol syndrome birth defects

A Specific LSD1/KDM1A Isoform Regulates Neuronal Differentiation through H3K9 Demethylation

(2015) Benoit Laurent et al.   MOLECULAR CELL

Restricted epigenetic inheritance of H3K9 methylation

(2015) P. N. C. B. Audergon et al.   SCIENCE

Alcohol Consumption During Gestation Causes Histone3 Lysine9 Hyperacetylation and an Alternation of Expression of Heart Development-Related Genes in Mice

(2014) Bo Pan et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

PGC1  Promoter Methylation in Blood at 5-7 Years Predicts Adiposity From 9 to 14 Years (EarlyBird 50)

(2014) R. Clarke-Harris et al.   DIABETES

5-Hydroxymethylation marks a class of neuronal gene regulated by intragenic methylcytosine levels

(2014) Rachelle E. Irwin et al.   GENOMICS

Effects of acute ethanol exposure on anxiety measures and epigenetic modifiers in the extended amygdala of adolescent rats

(2014) Amul J. Sakharkar et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

The Histone H3 Lysine 9 Methyltransferases G9a and GLP Regulate Polycomb Repressive Complex 2-Mediated Gene Silencing

(2014) Chiara Mozzetta et al.   MOLECULAR CELL

Epigenetic inheritance uncoupled from sequence-specific recruitment

(2014) K. Ragunathan et al.   SCIENCE

Epigenetic regulation of the neural transcriptome and alcohol interference during development

(2014) Marisol Resendiz et al.   Frontiers in Genetics

Identification of cell-specific patterns of reference gene stability in quantitative reverse-transcriptase polymerase chain reaction studies of embryonic, placental and neural stem models of prenatal ethanol exposure

(2013) Mindy N. Carnahan et al.   ALCOHOL

Gestational Choline Supplementation Normalized Fetal Alcohol-Induced Alterations in Histone Modifications, DNA Methylation, and Proopiomelanocortin (POMC) Gene Expression in β-Endorphin-Producing POMC Neurons of the Hypothalamus

(2013) Rola A. Bekdash et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Alcohol-Induced Epigenetic Alterations to Developmentally Crucial Genes Regulating Neural Stemness and Differentiation

(2013) Kylee J. Veazey et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Aberrant Histone Deacetylase2–Mediated Histone Modifications and Synaptic Plasticity in the Amygdala Predisposes to Anxiety and Alcoholism

(2013) Sachin Moonat et al.   BIOLOGICAL PSYCHIATRY

QChIPat: a quantitative method to identify distinct binding patterns for two biological ChIP-seq samples in different experimental conditions

(2013) Bin Liu et al.   BMC GENOMICS

PRDM14 promotes active DNA demethylation through the Ten-eleven translocation (TET)-mediated base excision repair pathway in embryonic stem cells

(2013) N. Okashita et al.   DEVELOPMENT

DROMPA: easy-to-handle peak calling and visualization software for the computational analysis and validation of ChIP-seq data

(2013) Ryuichiro Nakato et al.   GENES TO CELLS

Epigenetic mechanisms of drug addiction

(2013) Eric J. Nestler   NEUROPHARMACOLOGY

Ethanol induced acetylation of histone at G9a exon1 and G9a-mediated histone H3 dimethylation leads to neurodegeneration in neonatal mice

(2013) S. Subbanna et al.   NEUROSCIENCE

Genome-wide comparison of DNA hydroxymethylation in mouse embryonic stem cells and neural progenitor cells by a new comparative hMeDIP-seq method

(2013) Li Tan et al.   NUCLEIC ACIDS RESEARCH

TrxG and PcG Proteins but Not Methylated Histones Remain Associated with DNA through Replication

(2012) Svetlana Petruk et al.   CELL

Gene Coexpression Networks in Human Brain Identify Epigenetic Modifications in Alcohol Dependence

(2012) I. Ponomarev et al.   JOURNAL OF NEUROSCIENCE

Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation

(2012) Scott B Rothbart et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Effect of Preconception Paternal Alcohol Exposure on Epigenetic Remodeling of the H19 and Rasgrf1 Imprinting Control Regions in Mouse Offspring

(2012) Jaysen Gregory Knezovich et al.   Frontiers in Genetics

Alcohol Alters DNA Methylation Patterns and Inhibits Neural Stem Cell Differentiation

(2011) Feng C. Zhou et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Cellular DNA methylation program during neurulation and its alteration by alcohol exposure

(2011) Feng C. Zhou et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Alteration of gene expression by alcohol exposure at early neurulation

(2011) Feng C Zhou et al.   BMC GENOMICS

The role of oxidative stress in fetal alcohol spectrum disorders

(2011) Patricia S. Brocardo et al.   BRAIN RESEARCH REVIEWS

Jarid2 regulates mouse epidermal stem cell activation and differentiation

(2011) Stefania Mejetta et al.   EMBO JOURNAL

Histone H3K9 modifications are a local chromatin event involved in ethanol-induced neuroadaptation of the NR2B gene

(2011) Mei Qiang et al.   Epigenetics

Hypothesis: Environmental regulation of 5-hydroxymethylcytosine by oxidative stress

(2011) Nancy Chia et al.   Epigenetics

Stabilization of Suv39H1 by SirT1 Is Part of Oxidative Stress Response and Ensures Genome Protection

(2011) Laia Bosch-Presegué et al.   MOLECULAR CELL

What Choline Metabolism Can Tell Us About the Underlying Mechanisms of Fetal Alcohol Spectrum Disorders

(2011) Steven H. Zeisel   MOLECULAR NEUROBIOLOGY

Substance-specific and shared transcription and epigenetic changes in the human hippocampus chronically exposed to cocaine and alcohol

(2011) Z. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone modification: cause or cog?

(2011) Steven Henikoff et al.   TRENDS IN GENETICS

Subtle decreases in DNA methylation and gene expression at the mouse Igf2 locus following prenatal alcohol exposure: effects of a methyl-supplemented diet

(2010) Chris Downing et al.   ALCOHOL

Multiple Epigenetic Modifiers Induce Aggressive Viral Extinction in Extraembryonic Endoderm Stem Cells

(2010) Michael C. Golding et al.   Cell Stem Cell

Alcohol exposure alters DNA methylation profiles in mouse embryos at early neurulation

(2010) Yunlong Liu et al.   Epigenetics

Jarid2 and PRC2, partners in regulating gene expression

(2010) G. Li et al.   GENES & DEVELOPMENT

Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET

(2010) Toshiyuki Matsui et al.   NATURE

Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators

(2010) David Landeira et al.   NATURE CELL BIOLOGY

Ventromedian forebrain dysgenesis follows early prenatal ethanol exposure in mice

(2010) Elizabeth A. Godin et al.   NEUROTOXICOLOGY AND TERATOLOGY

Maternal Ethanol Consumption Alters the Epigenotype and the Phenotype of Offspring in a Mouse Model

(2010) Nina Kaminen-Ahola et al.   PLoS Genetics

Effect of Alcohol Consumption on CpG Methylation in the Differentially Methylated Regions ofH19andIG-DMRin Male Gametes-Implications for Fetal Alcohol Spectrum Disorders

(2009) Lillian A. Ouko et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Magnetic Resonance Microscopy Defines Ethanol-Induced Brain Abnormalities in Prenatal Mice: Effects of Acute Insult on Gestational Day 7

(2009) Elizabeth A. Godin et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Exposure of Mouse Embryos to Ethanol During Preimplantation Development: Effect on DNA Methylation in the H19 Imprinting Control Region1

(2009) Philip C. Haycock et al.   BIOLOGY OF REPRODUCTION

Altered gene expression in neural crest cells exposed to ethanol in vitro

(2009) Parri Wentzel et al.   BRAIN RESEARCH

KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints

(2009) David N. Ciccone et al.   NATURE

Role of the polycomb protein EED in the propagation of repressive histone marks

(2009) Raphael Margueron et al.   NATURE

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE

The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain

(2009) S. Kriaucionis et al.   SCIENCE

Nrf2-Mediated Transcriptional Induction of Antioxidant Response in Mouse Embryos Exposed to Ethanol in vivo: Implications for the Prevention of Fetal Alcohol Spectrum Disorders

(2008) Jian Dong et al.   ANTIOXIDANTS & REDOX SIGNALING

A model for transmission of the H3K27me3 epigenetic mark

(2008) Klaus H. Hansen et al.   NATURE CELL BIOLOGY

Chromatin immunoprecipitation (ChIP) coupled to detection by quantitative real-time PCR to study transcription factor binding to DNA in Caenorhabditis elegans

(2008) Arnab Mukhopadhyay et al.   Nature Protocols

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols