Loss of CD4 T-cell-dependent tolerance to proteins with modified amino acids

Conversion of Tyrosine to the Inflammation-Associated Analog 3′-Nitrotyrosine at Either TCR- or MHC-Contact Positions Can Profoundly Affect Recognition of the MHC Class I-Restricted Epitope of Lymphocytic Choriomeningitis Virus Glycoprotein 33 by CD8 T Cells

(2014) Lani L. Hardy et al.   JOURNAL OF IMMUNOLOGY

Novel combinations of Post-Translational Modification (PTM) neo-epitopes provide tissue-specific biochemical markers—are they the cause or the consequence of the disease?

(2010) Morten Asser Karsdal et al.   CLINICAL BIOCHEMISTRY

Contribution of Myelin Autoantigen Citrullination to T Cell Autoaggression in the Central Nervous System

(2010) A. Carrillo-Vico et al.   JOURNAL OF IMMUNOLOGY

Structural Basis for the Presentation of Tumor-Associated MHC Class II-Restricted Phosphopeptides to CD4+ T Cells

(2010) Yili Li et al.   JOURNAL OF MOLECULAR BIOLOGY

Goodpasture's Disease — New Secrets Revealed

(2010) David J. Salant   NEW ENGLAND JOURNAL OF MEDICINE

Molecular Architecture of the Goodpasture Autoantigen in Anti-GBM Nephritis

(2010) Vadim Pedchenko et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tumor-associated MUC1 glycopeptide epitopes are not subject to self-tolerance and improve responses to MUC1 peptide epitopes in MUC1 transgenic mice

(2009) Sean O. Ryan et al.   BIOLOGICAL CHEMISTRY

NN-align. An artificial neural network-based alignment algorithm for MHC class II peptide binding prediction

(2009) Morten Nielsen et al.   BMC BIOINFORMATICS

Efficient expression of tyrosine-sulfated proteins in E. coli using an expanded genetic code

(2009) Chang C Liu et al.   Nature Protocols

Identification of tumor-associated, MHC class II-restricted phosphopeptides as targets for immunotherapy

(2009) F. R. Depontieu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanistic studies of the immunochemical termination of self-tolerance with unnatural amino acids

(2009) J. Grunewald et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arthritis induced by posttranslationally modified (citrullinated) fibrinogen in DR4-IE transgenic mice

(2008) Jonathan A. Hill et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Genetically Encoding Protein Oxidative Damage

(2008) Heinz Neumann et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Phosphorylation-dependent interaction between antigenic peptides and MHC class I: a molecular basis for the presentation of transformed self

(2008) Fiyaz Mohammed et al.   NATURE IMMUNOLOGY

Immunochemical termination of self-tolerance

(2008) J. Grunewald et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Consequence of neo-antigenicity of the 'altered self'

(2008) P. Eggleton et al.   RHEUMATOLOGY

Epitope spreading to citrullinated antigens in mouse models of autoimmune arthritis and demyelination

(2008) Brian A Kidd et al.   ARTHRITIS RESEARCH & THERAPY

Circulating immune complexes contain citrullinated fibrinogen in rheumatoid arthritis

(2008) Xiaoyan Zhao et al.   ARTHRITIS RESEARCH & THERAPY

A Systematic Assessment of MHC Class II Peptide Binding Predictions and Evaluation of a Consensus Approach

(2008) Peng Wang et al.   PLoS Computational Biology