In vivo discovery of a peptide that prevents CUG-RNA hairpin formation and reverses RNA toxicity in myotonic dystrophy models
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Title
In vivo discovery of a peptide that prevents CUG-RNA hairpin formation and reverses RNA toxicity in myotonic dystrophy models
Authors
Keywords
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Journal
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Volume 108, Issue 29, Pages 11866-11871
Publisher
Proceedings of the National Academy of Sciences
Online
2011-07-06
DOI
10.1073/pnas.1018213108
References
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Note: Only part of the references are listed.- Aberrant alternative splicing and extracellular matrix gene expression in mouse models of myotonic dystrophy
- (2010) Hongqing Du et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Controlling the Specificity of Modularly Assembled Small Molecules for RNA via Ligand Module Spacing: Targeting the RNAs That Cause Myotonic Muscular Dystrophy
- (2009) Melissa M. Lee et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Rational Design of Ligands Targeting Triplet Repeating Transcripts That Cause RNA Dominant Disease: Application to Myotonic Muscular Dystrophy Type 1 and Spinocerebellar Ataxia Type 3
- (2009) Alexei Pushechnikov et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- A simple ligand that selectively targets CUG trinucleotide repeats and inhibits MBNL protein binding
- (2009) J. F. Arambula et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pentamidine reverses the splicing defects associated with myotonic dystrophy
- (2009) M. B. Warf et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Triplet-repeat oligonucleotide-mediated reversal of RNA toxicity in myotonic dystrophy
- (2009) S. A. M. Mulders et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The protein factors MBNL1 and U2AF65 bind alternative RNA structures to regulate splicing
- (2009) M. B. Warf et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Reversal of RNA Dominance by Displacement of Protein Sequestered on Triplet Repeat RNA
- (2009) T. M. Wheeler et al. SCIENCE
- Molecular Effects of the CTG Repeats in Mutant Dystrophia Myotonica Protein Kinase Gene
- (2008) Beatriz Llamusi et al. CURRENT GENOMICS
- Dynamic Combinatorial Selection of Molecules Capable of Inhibiting the (CUG) Repeat RNA−MBNL1 Interaction In Vitro: Discovery of Lead Compounds Targeting Myotonic Dystrophy (DM1)
- (2008) Peter C. Gareiss et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Structural insights into RNA recognition by the alternative-splicing regulator muscleblind-like MBNL1
- (2008) Marianna Teplova et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Genetic and Chemical Modifiers of a CUG Toxicity Model in Drosophila
- (2008) Amparo Garcia-Lopez et al. PLoS One
- Expanded CTG repeats within the DMPK 3' UTR causes severe skeletal muscle wasting in an inducible mouse model for myotonic dystrophy
- (2008) J. P. Orengo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart
- (2008) A. Kalsotra et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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