Evolution-guided discovery and recoding of allosteric pathway specificity determinants in psychoactive bioamine receptors

Evolutionary Trace Annotation Server: automated enzyme function prediction in protein structures using 3D templates

(2009) R. Matthew Ward et al.   BIOINFORMATICS

Agonist-Trafficking and Hallucinogens

(2009) Javier Gonzalez-Maeso et al.   CURRENT MEDICINAL CHEMISTRY

Evolutionary Trace Annotation of Protein Function in the Structural Proteome

(2009) Serkan Erdin et al.   JOURNAL OF MOLECULAR BIOLOGY

Role for the Regulator of G-Protein Signaling Homology Domain of G Protein-Coupled Receptor Kinases 5 and 6 in  2-Adrenergic Receptor and Rhodopsin Phosphorylation

(2009) F. Baameur et al.   MOLECULAR PHARMACOLOGY

Functional Rescue of β1-Adrenoceptor Dimerization and Trafficking by Pharmacological Chaperones

(2009) Hiroyuki Kobayashi et al.   TRAFFIC

Characterization of functional roles of DRY motif in the 2nd intracellular loop of dopamine D2 and D3 receptors

(2008) Ju-Heon Kim et al.   ARCHIVES OF PHARMACAL RESEARCH

Structural Basis for Ligand Binding and Specificity in Adrenergic Receptors: Implications for GPCR-Targeted Drug Discovery†

(2008) Thomas Huber et al.   BIOCHEMISTRY

Structure of a β1-adrenergic G-protein-coupled receptor

(2008) Tony Warne et al.   NATURE

De-Orphaning the Structural Proteome through Reciprocal Comparison of Evolutionarily Important Structural Features

(2008) R. Matthew Ward et al.   PLoS One

The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist

(2008) V.-P. Jaakola et al.   SCIENCE

Ligand-Stabilized Conformational States of Human β2 Adrenergic Receptor: Insight into G-Protein-Coupled Receptor Activation

(2007) Supriyo Bhattacharya et al.   BIOPHYSICAL JOURNAL