Physiologically Based Pharmacokinetic Predictions of Tramadol Exposure Throughout Pediatric Life: an Analysis of the Different Clearance Contributors with Emphasis on CYP2D6 Maturation

Published 2015 View Full Article

Authors

Keywords

clearance, ontogeny, PBPK, pediatric, tramadol

Journal

AAPS Journal

Volume 17, Issue 6, Pages 1376-1387

Publisher

American Association of Pharmaceutical Scientists (AAPS)

Online

2015-07-25

DOI

10.1208/s12248-015-9803-z

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