Interactions between muscle stem cells, mesenchymal-derived cells and immune cells in muscle homeostasis, regeneration and disease

GDF11 Increases with Age and Inhibits Skeletal Muscle Regeneration

(2015) Marc A. Egerman et al.   Cell Metabolism

The NAD+-Dependent SIRT1 Deacetylase Translates a Metabolic Switch into Regulatory Epigenetics in Skeletal Muscle Stem Cells

(2015) James G. Ryall et al.   Cell Stem Cell

Characterization of adipocytes derived from fibro/adipogenic progenitors resident in human skeletal muscle

(2015) N Arrighi et al.   Cell Death & Disease

The skeletal muscle satellite cell response to a single bout of resistance-type exercise is delayed with aging in men

(2014) Tim Snijders et al.   AGE

Muscle ectopic fat deposition contributes to anabolic resistance in obese sarcopenic old rats through eIF2α activation

(2014) Nicolas Tardif et al.   AGING CELL

Obesity paradox in cancer: new insights provided by body composition

(2014) Maria Cristina Gonzalez et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Whey protein supplementation accelerates satellite cell proliferation during recovery from eccentric exercise

(2014) Jean Farup et al.   AMINO ACIDS

Eosinophils and Type 2 Cytokine Signaling in Macrophages Orchestrate Development of Functional Beige Fat

(2014) Yifu Qiu et al.   CELL

Meteorin-like Is a Hormone that Regulates Immune-Adipose Interactions to Increase Beige Fat Thermogenesis

(2014) Rajesh R. Rao et al.   CELL

Eosinophils in Fat: Pink Is the New Brown

(2014) Stephen D. Lee et al.   CELL

Shared signaling systems in myeloid cell-mediated muscle regeneration

(2014) J. G. Tidball et al.   DEVELOPMENT

Induction of autophagy supports the bioenergetic demands of quiescent muscle stem cell activation

(2014) Ann H Tang et al.   EMBO JOURNAL

Cardiovascular disease in patients with chronic inflammation: mechanisms underlying premature cardiovascular events in rheumatologic conditions

(2014) J. C. Mason et al.   EUROPEAN HEART JOURNAL

Glucocorticoids increase adipocytes in muscle by affecting IL-4 regulated FAP activity

(2014) Yanjun Dong et al.   FASEB JOURNAL

HDAC-regulated myomiRs control BAF60 variant exchange and direct the functional phenotype of fibro-adipogenic progenitors in dystrophic muscles

(2014) V. Saccone et al.   GENES & DEVELOPMENT

Influence of exercise contraction mode and protein supplementation on human skeletal muscle satellite cell content and muscle fiber growth

(2014) Jean Farup et al.   JOURNAL OF APPLIED PHYSIOLOGY

The role of satellite cells in muscle hypertrophy

(2014) Bert Blaauw et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

Fibre type-specific satellite cell response to aerobic training in sedentary adults

(2014) Christopher S. Fry et al.   JOURNAL OF PHYSIOLOGY-LONDON

Geriatric muscle stem cells switch reversible quiescence into senescence

(2014) Pedro Sousa-Victor et al.   NATURE

Inhibition of JAK-STAT signaling stimulates adult satellite cell function

(2014) Feodor D Price et al.   NATURE MEDICINE

Rejuvenation of the muscle stem cell population restores strength to injured aged muscles

(2014) Benjamin D Cosgrove et al.   NATURE MEDICINE

Inducible depletion of satellite cells in adult, sedentary mice impairs muscle regenerative capacity without affecting sarcopenia

(2014) Christopher S Fry et al.   NATURE MEDICINE

p38 MAPK signaling underlies a cell-autonomous loss of stem cell self-renewal in skeletal muscle of aged mice

(2014) Jennifer D Bernet et al.   NATURE MEDICINE

Ectopic Fat in Insulin Resistance, Dyslipidemia, and Cardiometabolic Disease

(2014) Gerald I. Shulman   NEW ENGLAND JOURNAL OF MEDICINE

Mechanisms involved in attenuated cardio-protective role of ischemic preconditioning in metabolic disorders

(2014) A Rana et al.   PERFUSION-UK

Regenerative defect in vastus lateralis muscle of patients with chronic obstructive pulmonary disease

(2014) Marie-Eve Thériault et al.   RESPIRATORY RESEARCH

Restoring Systemic GDF11 Levels Reverses Age-Related Dysfunction in Mouse Skeletal Muscle

(2014) M. Sinha et al.   SCIENCE

A Wnt-TGF 2 axis induces a fibrogenic program in muscle stem cells from dystrophic mice

(2014) S. Biressi et al.   Science Translational Medicine

The immunomodulating role of exercise in metabolic disease

(2014) Graeme I. Lancaster et al.   TRENDS IN IMMUNOLOGY

Deficits in Muscle Mass, Muscle Density, and Modified Associations With Fat in Rheumatoid Arthritis

(2014) Joshua F. Baker et al.   ARTHRITIS CARE & RESEARCH

Identification and characterization of PDGFRα+ mesenchymal progenitors in human skeletal muscle

(2014) A Uezumi et al.   Cell Death & Disease

Oxytocin is an age-specific circulating hormone that is necessary for muscle maintenance and regeneration

(2014) Christian Elabd et al.   Nature Communications

From Innate to Adaptive Immune Response in Muscular Dystrophies and Skeletal Muscle Regeneration: The Role of Lymphocytes

(2014) Luca Madaro et al.   Biomed Research International

Roles of nonmyogenic mesenchymal progenitors in pathogenesis and regeneration of skeletal muscle

(2014) Akiyoshi Uezumi et al.   Frontiers in Physiology

Structural alterations of skeletal muscle in copd

(2014) Sunita Mathur et al.   Frontiers in Physiology

Differential satellite cell density of type I and II fibres with lifelong endurance running in old men

(2013) A. L. Mackey et al.   Acta Physiologica

Satellite cells in human skeletal muscle; from birth to old age

(2013) Lex B. Verdijk et al.   AGE

Whole body metabolic effects of prolonged endurance training in combination with erythropoietin treatment in humans: a randomized placebo controlled trial

(2013) Britt Christensen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Age-dependent alteration in muscle regeneration: the critical role of tissue niche

(2013) Laura Barberi et al.   BIOGERONTOLOGY

Type 2 Innate Signals Stimulate Fibro/Adipogenic Progenitors to Facilitate Muscle Regeneration

(2013) Jose E. Heredia et al.   CELL

Expression of anti-inflammatory macrophage genes within skeletal muscle correlates with insulin sensitivity in human obesity and type 2 diabetes

(2013) L. N. Fink et al.   DIABETOLOGIA

Fibroadipogenic progenitors mediate the ability of HDAC inhibitors to promote regeneration in dystrophic muscles of young, but not old Mdx mice

(2013) Chiara Mozzetta et al.   EMBO Molecular Medicine

Cellular dynamics in the muscle satellite cell niche

(2013) C Florian Bentzinger et al.   EMBO REPORTS

Evidence for the contribution of muscle stem cells to nonhypertrophic skeletal muscle remodeling in humans

(2013) Sophie Joanisse et al.   FASEB JOURNAL

Regulation of the muscle fiber microenvironment by activated satellite cells during hypertrophy

(2013) Christopher S. Fry et al.   FASEB JOURNAL

Tissue-resident mesenchymal stem/progenitor cells in skeletal muscle: collaborators or saboteurs?

(2013) Robert N. Judson et al.   FEBS Journal

Lying low but ready for action: the quiescent muscle satellite cell

(2013) Didier Montarras et al.   FEBS Journal

Interleukin-6 myokine signaling in skeletal muscle: a double-edged sword?

(2013) Pura Muñoz-Cánoves et al.   FEBS Journal

Triggers and mechanisms of skeletal muscle wasting in chronic obstructive pulmonary disease

(2013) R.C.J. Langen et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Normal physical activity obliterates the deleterious effects of a high-caloric intake

(2013) Rikke Krogh-Madsen et al.   JOURNAL OF APPLIED PHYSIOLOGY

Deficits in Muscle Strength, Mass, Quality, and Mobility in People With Chronic Obstructive Pulmonary Disease

(2013) Marc Roig et al.   Journal of Cardiopulmonary Rehabilitation and Prevention

Human skeletal muscle fibroblasts, but not myogenic cells, readily undergo adipogenic differentiation

(2013) Chibeza C. Agley et al.   JOURNAL OF CELL SCIENCE

Body Composition Variation and Impact of Low Skeletal Muscle Mass in Patients With Advanced Medullary Thyroid Carcinoma Treated With Vandetanib: Results From a Placebo-Controlled Study

(2013) Marie-Hélène Massicotte et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

NF-κB–mediated Pax7 dysregulation in the muscle microenvironment promotes cancer cachexia

(2013) Wei A. He et al.   JOURNAL OF CLINICAL INVESTIGATION

Cancer Cachexia in the Age of Obesity: Skeletal Muscle Depletion Is a Powerful Prognostic Factor, Independent of Body Mass Index

(2013) Lisa Martin et al.   JOURNAL OF CLINICAL ONCOLOGY

Depletion of stromal cells expressing fibroblast activation protein-α from skeletal muscle and bone marrow results in cachexia and anemia

(2013) Edward W. Roberts et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Interleukin-4 regulates lipid metabolism by inhibiting adipogenesis and promoting lipolysis

(2013) Chang-Hui Tsao et al.   JOURNAL OF LIPID RESEARCH

Acute Dietary Protein Intake Restriction Is Associated with Changes in Myostatin Expression after a Single Bout of Resistance Exercise in Healthy Young Men

(2013) Tim Snijders et al.   JOURNAL OF NUTRITION

Ageing is associated with diminished muscle re-growth and myogenic precursor cell expansion early after immobility-induced atrophy in human skeletal muscle

(2013) C. Suetta et al.   JOURNAL OF PHYSIOLOGY-LONDON

Patients With Type 2 Diabetes Show a Greater Decline in Muscle Mass, Muscle Strength, and Functional Capacity With Aging

(2013) Marika Leenders et al.   Journal of the American Medical Directors Association

Life-long endurance exercise in humans: Circulating levels of inflammatory markers and leg muscle size

(2013) U.R. Mikkelsen et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Metabolic Syndrome in Rheumatoid Arthritis

(2013) Iván Ferraz-Amaro et al.   MEDIATORS OF INFLAMMATION

Satellite Cells and the Muscle Stem Cell Niche

(2013) Hang Yin et al.   PHYSIOLOGICAL REVIEWS

Early Activation of Rat Skeletal Muscle IL-6/STAT1/STAT3 Dependent Gene Expression in Resistance Exercise Linked to Hypertrophy

(2013) Gwénaëlle Begue et al.   PLoS One

Osteogenic Differentiation Capacity of Human Skeletal Muscle-Derived Progenitor Cells

(2013) Teruyo Oishi et al.   PLoS One

Pax7 is critical for the normal function of satellite cells in adult skeletal muscle

(2013) J. von Maltzahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nitric Oxide Controls Fat Deposition in Dystrophic Skeletal Muscle by Regulating Fibro-Adipogenic Precursor Differentiation

(2013) Nicoletta Cordani et al.   STEM CELLS

The effects of obesity on skeletal muscle regeneration

(2013) Dmitry Akhmedov et al.   Frontiers in Physiology

Diabetic myopathy: impact of diabetes mellitus on skeletal muscle progenitor cells

(2013) Donna M. D'Souza et al.   Frontiers in Physiology

Mechanisms for Insulin Resistance: Common Threads and Missing Links

(2012) Varman T. Samuel et al.   CELL

Srf-Dependent Paracrine Signals Produced by Myofibers Control Satellite Cell-Mediated Skeletal Muscle Hypertrophy

(2012) Aline Guerci et al.   Cell Metabolism

Tissue-Specific Stem Cells: Lessons from the Skeletal Muscle Satellite Cell

(2012) Andrew S. Brack et al.   Cell Stem Cell

A single bout of exercise activates skeletal muscle satellite cells during subsequent overnight recovery

(2012) Tim Snijders et al.   EXPERIMENTAL PHYSIOLOGY

Myostatin is associated with age-related human muscle stem cell dysfunction

(2012) Bryon R. McKay et al.   FASEB JOURNAL

Low-intensity exercise can increase muscle mass and strength proportionally to enhanced metabolic stress under ischemic conditions

(2012) Shingo Takada et al.   JOURNAL OF APPLIED PHYSIOLOGY

Muscle characteristics in patients with chronic systemic inflammation

(2012) Karel G.M. Beenakker et al.   MUSCLE & NERVE

The aged niche disrupts muscle stem cell quiescence

(2012) Joe V. Chakkalakal et al.   NATURE

Satellite Cells Senescence in Limb Muscle of Severe Patients with COPD

(2012) Marie-Eve Thériault et al.   PLoS One

Differentially Activated Macrophages Orchestrate Myogenic Precursor Cell Fate During Human Skeletal Muscle Regeneration

(2012) Marielle Saclier et al.   STEM CELLS

Chemotherapy-Induced Weakness and Fatigue in Skeletal Muscle: The Role of Oxidative Stress

(2011) Laura A.A. Gilliam et al.   ANTIOXIDANTS & REDOX SIGNALING

Regeneration versus fibrosis in skeletal muscle

(2011) Adam L. Moyer et al.   CURRENT OPINION IN RHEUMATOLOGY

Pax7-expressing satellite cells are indispensable for adult skeletal muscle regeneration

(2011) R. Sambasivan et al.   DEVELOPMENT

An absolute requirement for Pax7-positive satellite cells in acute injury-induced skeletal muscle regeneration

(2011) C. Lepper et al.   DEVELOPMENT

Effective fiber hypertrophy in satellite cell-depleted skeletal muscle

(2011) J. J. McCarthy et al.   DEVELOPMENT

Skeletal Muscle Triglycerides, Diacylglycerols, and Ceramides in Insulin Resistance: Another Paradox in Endurance-Trained Athletes?

(2011) F. Amati et al.   DIABETES

Signal-dependent incorporation of MyoD-BAF60c into Brg1-based SWI/SNF chromatin-remodelling complex

(2011) Sonia V Forcales et al.   EMBO JOURNAL

Regulation of glucose/lipid metabolism and insulin sensitivity by interleukin-4

(2011) Y-H Chang et al.   INTERNATIONAL JOURNAL OF OBESITY

Fibrosis and adipogenesis originate from a common mesenchymal progenitor in skeletal muscle

(2011) A. Uezumi et al.   JOURNAL OF CELL SCIENCE

Adipose tissue remodeling and obesity

(2011) Kai Sun et al.   JOURNAL OF CLINICAL INVESTIGATION

Strength training increases the size of the satellite cell pool in type I and II fibres of chronically painful trapezius muscle in females

(2011) Abigail L. Mackey et al.   JOURNAL OF PHYSIOLOGY-LONDON

Eosinophils Sustain Adipose Alternatively Activated Macrophages Associated with Glucose Homeostasis

(2011) D. Wu et al.   SCIENCE

Regenerative potential of human muscle stem cells in chronic inflammation

(2011) Bouke J Duijnisveld et al.   ARTHRITIS RESEARCH & THERAPY

Intramyocellular lipid droplets increase with progression of cachexia in cancer patients

(2011) Nathan A. Stephens et al.   Journal of Cachexia Sarcopenia and Muscle

Patterns of muscle strength loss with age in the general population and patients with a chronic inflammatory state

(2010) Karel G.M. Beenakker et al.   AGEING RESEARCH REVIEWS

Aging and its effects on inflammation in skeletal muscle at rest and following exercise-induced muscle injury

(2010) Jonathan Peake et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Low body mass index and sarcopenia associated with dose-limiting toxicity of sorafenib in patients with renal cell carcinoma

(2010) S. Antoun et al.   ANNALS OF ONCOLOGY

Fibro/adipogenic progenitors: A double-edged sword in skeletal muscle regeneration

(2010) Anuradha Natarajan et al.   CELL CYCLE

MicroRNAs Involved in Molecular Circuitries Relevant for the Duchenne Muscular Dystrophy Pathogenesis Are Controlled by the Dystrophin/nNOS Pathway

(2010) Davide Cacchiarelli et al.   Cell Metabolism

TNF/p38α/Polycomb Signaling to Pax7 Locus in Satellite Cells Links Inflammation to the Epigenetic Control of Muscle Regeneration

(2010) Daniela Palacios et al.   Cell Stem Cell

Increased adipogenic conversion of muscle satellite cells in obese Zucker rats

(2010) A Scarda et al.   INTERNATIONAL JOURNAL OF OBESITY

Repairing skeletal muscle: regenerative potential of skeletal muscle stem cells

(2010) Francesco Saverio Tedesco et al.   JOURNAL OF CLINICAL INVESTIGATION

Association of Skeletal Muscle Wasting With Treatment With Sorafenib in Patients With Advanced Renal Cell Carcinoma: Results From a Placebo-Controlled Study

(2010) Sami Antoun et al.   JOURNAL OF CLINICAL ONCOLOGY

Association of interleukin-4 promoter polymorphisms in Taiwanese patients with type 2 diabetes mellitus

(2010) Kuo-Ting Ho et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Continuous endurance-type exercise training does not modulate satellite cell content in obese type 2 diabetes patients

(2010) Tim Snijders et al.   MUSCLE & NERVE

Tipping the scale: muscle versus fat

(2010) Matthew S. Rodeheffer   NATURE CELL BIOLOGY

Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle

(2010) Akiyoshi Uezumi et al.   NATURE CELL BIOLOGY

Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis

(2010) Aaron W. B. Joe et al.   NATURE CELL BIOLOGY

Myonuclei acquired by overload exercise precede hypertrophy and are not lost on detraining

(2010) J. C. Bruusgaard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myogenic response of human skeletal muscle to 12 weeks of resistance training at light loading intensity

(2010) A. L. Mackey et al.   SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS

The effect of androgen deprivation therapy on body composition in men with prostate cancer: Systematic review and meta-analysis

(2010) Farhana Haseen et al.   Journal of Cancer Survivorship

The impact of sarcopenia and exercise training on skeletal muscle satellite cells

(2009) Tim Snijders et al.   AGEING RESEARCH REVIEWS

A role for calcium-calmodulin in regulating nitric oxide production during skeletal muscle satellite cell activation

(2009) Ryuichi Tatsumi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The origin of intermuscular adipose tissue and its pathophysiological implications

(2009) Roberto Vettor et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Sarcopenia as a Determinant of Chemotherapy Toxicity and Time to Tumor Progression in Metastatic Breast Cancer Patients Receiving Capecitabine Treatment

(2009) C. M.M. Prado et al.   CLINICAL CANCER RESEARCH

Molecular aging and rejuvenation of human muscle stem cells

(2009) Morgan E. Carlson et al.   EMBO Molecular Medicine

Update on emerging drugs for cancer cachexia

(2009) Kate T Murphy et al.   EXPERT OPINION ON EMERGING DRUGS

Local NSAID infusion inhibits satellite cell proliferation in human skeletal muscle after eccentric exercise

(2009) U. R. Mikkelsen et al.   JOURNAL OF APPLIED PHYSIOLOGY

The Pathogenetic Role of Cortisol in the Metabolic Syndrome: A Hypothesis

(2009) Panagiotis Anagnostis et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Skeletal Muscle Hypertrophy Following Resistance Training Is Accompanied by a Fiber Type-Specific Increase in Satellite Cell Content in Elderly Men

(2009) L. B. Verdijk et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

The role of systemic inflammation in age-related muscle weakness and wasting

(2009) H. Degens   SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS

Stem Cell Review Series: Aging of the skeletal muscle stem cell niche

(2008) Suchitra D. Gopinath et al.   AGING CELL

Cachexia: A new definition

(2008) William J. Evans et al.   CLINICAL NUTRITION

Alterations in Muscle Attenuation following Detraining and Retraining in Resistance-Trained Older Adults

(2008) Dennis R. Taaffe et al.   GERONTOLOGY

Effects of physical activity on strength and skeletal muscle fat infiltration in older adults: a randomized controlled trial

(2008) Bret H. Goodpaster et al.   JOURNAL OF APPLIED PHYSIOLOGY

Potent myofiber hypertrophy during resistance training in humans is associated with satellite cell-mediated myonuclear addition: a cluster analysis

(2008) John K. Petrella et al.   JOURNAL OF APPLIED PHYSIOLOGY

Lower Visceral and Subcutaneous but Higher Intermuscular Adipose Tissue Depots in Patients with Growth Hormone and Insulin-Like Growth Factor I Excess Due to Acromegaly

(2008) Pamela U. Freda et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Co-expression of IGF-1 family members with myogenic regulatory factors following acute damaging muscle-lengthening contractions in humans

(2008) Bryon R. McKay et al.   JOURNAL OF PHYSIOLOGY-LONDON

Prevalence and clinical implications of sarcopenic obesity in patients with solid tumours of the respiratory and gastrointestinal tracts: a population-based study

(2008) Carla MM Prado et al.   LANCET ONCOLOGY

Effects of combined lower body endurance and upper body resistance training on the satellite cell pool in elderly subjects

(2008) Julien Verney et al.   MUSCLE & NERVE

Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells

(2008) Morgan E. Carlson et al.   NATURE

Excessive Adipose Tissue Infiltration in Skeletal Muscle in Individuals With Obesity, Diabetes Mellitus, and Peripheral Neuropathy: Association With Performance and Function

(2008) Tiffany N Hilton et al.   PHYSICAL THERAPY

HDAC2 blockade by nitric oxide and histone deacetylase inhibitors reveals a common target in Duchenne muscular dystrophy treatment

(2008) C. Colussi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High glucose induces adipogenic differentiation of muscle-derived stem cells

(2008) P. Aguiari et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA