Gankyrin drives malignant transformation of chronic liver damage-mediated fibrosis via the Rac1/JNK pathway

The therapeutic value of targeting inflammation in gastrointestinal cancers

(2014) Beicheng Sun et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Overexpression of gankyrin in mouse hepatocytes induces hemangioma by suppressing factor inhibiting hypoxia-inducible factor-1 (FIH-1) and activating hypoxia-inducible factor-1

(2013) Yu Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Multiple interactive factors in hepatocarcinogenesis

(2013) Jin Ding et al.   CANCER LETTERS

p53 promotes inflammation-associated hepatocarcinogenesis by inducing HMGB1 release

(2013) He-Xin Yan et al.   JOURNAL OF HEPATOLOGY

Recent advances in understanding inflammation and remodeling in the airways in chronic obstructive pulmonary disease

(2013) Sukhwinder Singh Sohal et al.   Expert Review of Respiratory Medicine

From Cirrhosis to Hepatocellular Carcinoma: New Molecular Insights on Inflammation and Cellular Senescence

(2013) Gayatri Ramakrishna et al.   Liver Cancer

Promotion of Hepatocellular Carcinoma by the Intestinal Microbiota and TLR4

(2012) Dianne H. Dapito et al.   CANCER CELL

p28GANK Prevents Degradation of Oct4 and Promotes Expansion of Tumor-Initiating Cells in Hepatocarcinogenesis

(2012) You–Wen Qian et al.   GASTROENTEROLOGY

Gankyrin promotes breast cancer cell metastasis by regulating Rac1 activity

(2012) C Zhen et al.   ONCOGENE

Cellular Function of RhoGDI-α Mediates the Cycling of Rac1 and the Regulation of Pancreatic Beta Cell Death

(2012) Y. Cho et al.   TRANSPLANTATION PROCEEDINGS

The role of JNK in the development of hepatocellular carcinoma

(2011) Madhumita Das et al.   GENES & DEVELOPMENT

Gankyrin-mediated dedifferentiation facilitates the tumorigenicity of rat hepatocytes and hepatoma cells

(2011) Wen Sun et al.   HEPATOLOGY

p28GANK overexpression accelerates hepatocellular carcinoma invasiveness and metastasis via phosphoinositol 3-kinase/AKT/hypoxia-inducible factor-1α pathways

(2010) Jing Fu et al.   HEPATOLOGY

Endotoxin accumulation prevents carcinogen-induced apoptosis and promotes liver tumorigenesis in rodents

(2010) Le-Xing Yu et al.   HEPATOLOGY

The protective role of hydrogen-rich saline in experimental liver injury in mice

(2010) HanYong Sun et al.   JOURNAL OF HEPATOLOGY

Evolving challenges in hepatic fibrosis

(2010) Scott L. Friedman   Nature Reviews Gastroenterology & Hepatology

Mouse Models of Hepatocellular Carcinoma

(2010) Nelson Fausto et al.   SEMINARS IN LIVER DISEASE

Modulation of Hepatic Fibrosis by c-Jun-N-Terminal Kinase Inhibition

(2009) Johannes Kluwe et al.   GASTROENTEROLOGY

TNF-α/cycloheximide-induced apoptosis in intestinal epithelial cells requires Rac1-regulated reactive oxygen species

(2008) Shi Jin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Rac Activation and Inactivation Control Plasticity of Tumor Cell Movement

(2008) Victoria Sanz-Moreno et al.   CELL

Proliferation of human HCC cells and chemically induced mouse liver cancers requires JNK1-dependent p21 downregulation

(2008) Lijian Hui et al.   JOURNAL OF CLINICAL INVESTIGATION

Experimental models of hepatocellular carcinoma

(2008) Philippa Newell et al.   JOURNAL OF HEPATOLOGY

Sorafenib in Advanced Hepatocellular Carcinoma

(2008) Josep M. Llovet et al.   NEW ENGLAND JOURNAL OF MEDICINE