A pro-apoptotic function of iASPP by stabilizing p300 and CBP through inhibition of BRMS1 E3 ubiquitin ligase activity

iASPP is a novel autophagy inhibitor in keratinocytes

(2014) A. Chikh et al.   JOURNAL OF CELL SCIENCE

Restoring p53 Function in Human Melanoma Cells by Inhibiting MDM2 and Cyclin B1/CDK1-Phosphorylated Nuclear iASPP

(2013) Min Lu et al.   CANCER CELL

The C-Terminal Putative Nuclear Localization Sequence of BReast cancer Metastasis Suppressor 1, BRMS1, Is Necessary for Metastasis Suppression

(2013) Douglas R. Hurst et al.   PLoS One

Decreased Expression of Nuclear p300 Is Associated with Disease Progression and Worse Prognosis of Melanoma Patients

(2013) Anand Rotte et al.   PLoS One

iASPP inhibits p53-independent apoptosis by inhibiting transcriptional activity of p63/p73 on promoters of proapoptotic genes

(2012) Yun Cai et al.   APOPTOSIS

Cytoplasmic BRMS1 expression in malignant melanoma is associated with increased disease-free survival

(2012) Ana Slipicevic et al.   BMC CANCER

BRMS1 Suppresses Lung Cancer Metastases through an E3 Ligase Function on Histone Acetyltransferase p300

(2012) Y. Liu et al.   CANCER RESEARCH

p63/p73 in the control of cell cycle and cell death

(2012) N. Allocati et al.   EXPERIMENTAL CELL RESEARCH

p38 MAPK- and Akt-mediated p300 phosphorylation regulates its degradation to facilitate nucleotide excision repair

(2012) Qi-En Wang et al.   NUCLEIC ACIDS RESEARCH

The ASPP proteins complex and cooperate with p300 to modulate the transcriptional activity of p53

(2011) Sébastien Gillotin et al.   FEBS LETTERS

Cytoplasmic ASPP1 inhibits apoptosis through the control of YAP

(2010) A. M. Vigneron et al.   GENES & DEVELOPMENT

Characterization of genome-wide p53-binding sites upon stress response

(2008) Leonie Smeenk et al.   NUCLEIC ACIDS RESEARCH

Biochemical and Structural Studies of ASPP Proteins Reveal Differential Binding to p53, p63, and p73

(2008) Ross Alexander Robinson et al.   STRUCTURE