PAK1 regulates RUFY3-mediated gastric cancer cell migration and invasion

Rufy3, a protein specifically expressed in neurons, interacts with actin-bundling protein Fascin to control the growth of axons

(2014) Zhe Wei et al.   JOURNAL OF NEUROCHEMISTRY

Group I PAK Inhibitor IPA-3 Induces Cell Death and Affects Cell Adhesivity to Fibronectin in Human Hematopoietic Cells

(2014) Kateřina Kuželová et al.   PLoS One

RUFY, Rab and Rap Family Proteins Involved in a Regulation of Cell Polarity and Membrane Trafficking

(2013) Yasuko Kitagishi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

PAK4 kinase-mediated SCG10 phosphorylation involved in gastric cancer metastasis

(2013) Q Guo et al.   ONCOGENE

IPA-3 Inhibits the Growth of Liver Cancer Cells By Suppressing PAK1 and NF-κB Activation

(2013) Leo Lap-Yan Wong et al.   PLoS One

Rab5(Q79L) interacts with the carboxyl terminus of RUFY3

(2012) Hitomi Yoshida et al.   International Journal of Biological Sciences

Group I p21-Activated Kinases (PAKs) Promote Tumor Cell Proliferation and Survival through the AKT1 and Raf-MAPK Pathways

(2012) C. W. Menges et al.   MOLECULAR CANCER RESEARCH

PAK1 Kinase Promotes Cell Motility and Invasiveness through CRK-II Serine Phosphorylation in Non-Small Cell Lung Cancer Cells

(2012) Matthew Rettig et al.   PLoS One

Crystal structure and functional implication of the RUN domain of human NESCA

(2012) Qifan Sun et al.   Protein & Cell

LCH-7749944, a novel and potent p21-activated kinase 4 inhibitor, suppresses proliferation and invasion in human gastric cancer cells

(2011) Jian Zhang et al.   CANCER LETTERS

Genome-wide Investigation of the Rab Binding Activity of RUN Domains: Development of a Novel Tool that Specifically Traps GTP-Rab35

(2011) Mitsunori Fukuda et al.   CELL STRUCTURE AND FUNCTION

Curcumin suppresses proliferation and invasion in human gastric cancer cells by down-regulation of PAK1 activity and cyclin D1 expression

(2010) Xin-Ze Cai et al.   CANCER BIOLOGY & THERAPY

Functional Cross-Talk between Rab14 and Rab4 through a Dual Effector, RUFY1/Rabip4

(2010) Hideaki Yamamoto et al.   MOLECULAR BIOLOGY OF THE CELL

Targeting group II PAKs in cancer and metastasis

(2009) Jeyanthy Eswaran et al.   CANCER AND METASTASIS REVIEWS

Downregulation of p21-activated kinase-1 inhibits the growth of gastric cancer cells involving cyclin B1

(2009) Funan Liu et al.   INTERNATIONAL JOURNAL OF CANCER

An Isoform-Selective, Small-Molecule Inhibitor Targets the Autoregulatory Mechanism of p21-Activated Kinase

(2008) Sean W. Deacon et al.   CHEMISTRY & BIOLOGY