Role of proteolytic activation of protein kinase Cδ in the pathogenesis of prion disease

Mitochondria-targeted antioxidants for treatment of Parkinson's disease: Preclinical and clinical outcomes

(2013) Huajun Jin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Cytosolic caspases mediate mislocalised SOD2 depletion in an in vitro model of chronic prion infection

(2013) L. Sinclair et al.   Disease Models & Mechanisms

The Peptidyl-prolyl Isomerase Pin1 Up-regulation and Proapoptotic Function in Dopaminergic Neurons

(2013) Anamitra Ghosh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cellular Prion Protein (PrPC) of the Neuron Cell Transformed to a PK-Resistant Protein Under Oxidative Stress, Comprising Main Mitochondrial Damage in Prion Diseases

(2013) Fangzhong Yuan et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein

(2013) Tiziana Sonati et al.   NATURE

Measuring the Strength of Mice

(2013) Robert M.J. Deacon   Jove-Journal of Visualized Experiments

Proteolytic activation of proapoptotic kinase protein kinase Cδ by tumor necrosis factor α death receptor signaling in dopaminergic neurons during neuroinflammation

(2012) Richard Gordon et al.   Journal of Neuroinflammation

Methamphetamine-induced neurotoxicity linked to ubiquitin-proteasome system dysfunction and autophagy-related changes that can be modulated by protein kinase C delta in dopaminergic neuronal cells

(2012) M. Lin et al.   NEUROSCIENCE

Organotypic Brain Slice Cultures of Adult Transgenic P301S Mice—A Model for Tauopathy Studies

(2012) Agneta Mewes et al.   PLoS One

Effect of divalent metals on the neuronal proteasomal system, prion protein ubiquitination and aggregation

(2012) A.G. Kanthasamy et al.   TOXICOLOGY LETTERS

Prion Pathogenesis Is Faithfully Reproduced in Cerebellar Organotypic Slice Cultures

(2012) Jeppe Falsig et al.   PLoS Pathogens

Transcriptional Regulation of Pro-apoptotic Protein Kinase Cδ

(2011) Huajun Jin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Spongiform Encephalopathy in Transgenic Mice Expressing a Point Mutation in the  2- 2 Loop of the Prion Protein

(2011) C. J. Sigurdson et al.   JOURNAL OF NEUROSCIENCE

 -Synuclein Negatively Regulates Protein Kinase C  Expression to Suppress Apoptosis in Dopaminergic Neurons by Reducing p300 Histone Acetyltransferase Activity

(2011) H. Jin et al.   JOURNAL OF NEUROSCIENCE

Infectious prion protein alters manganese transport and neurotoxicity in a cell culture model of prion disease

(2011) Dustin P. Martin et al.   NEUROTOXICOLOGY

Environmental neurotoxic pesticide dieldrin activates a non receptor tyrosine kinase to promote pkcδ-mediated dopaminergic apoptosis in a dopaminergic neuronal cell model

(2011) Hariharan Saminathan et al.   NEUROTOXICOLOGY

Transmission of Chronic Wasting Disease Identifies a Prion Strain Causing Cachexia and Heart Infection in Hamsters

(2011) Richard A. Bessen et al.   PLoS One

Dopaminergic neurotoxicant 6-OHDA induces oxidative damage through proteolytic activation of PKCδ in cell culture and animal models of Parkinson's disease

(2011) Calivarathan Latchoumycandane et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

A Simple Composite Phenotype Scoring System for Evaluating Mouse Models of Cerebellar Ataxia

(2010) Stephan J. Guyenet et al.   Jove-Journal of Visualized Experiments

Novel cell death signaling pathways in neurotoxicity models of dopaminergic degeneration: Relevance to oxidative stress and neuroinflammation in Parkinson's disease

(2009) Anumantha Kanthasamy et al.   NEUROTOXICOLOGY

The Prion's Elusive Reason for Being

(2008) Adriano Aguzzi et al.   Annual Review of Neuroscience

Cell-free propagation of prion strains

(2008) Joaquín Castilla et al.   EMBO JOURNAL

Opposing roles of prion protein in oxidative stress- and ER stress-induced apoptotic signaling

(2008) Vellareddy Anantharam et al.   FREE RADICAL BIOLOGY AND MEDICINE

Increased oxidation, glycoxidation, and lipoxidation of brain proteins in prion disease

(2008) Reinald Pamplona et al.   FREE RADICAL BIOLOGY AND MEDICINE

Investigation of Mcp1 as a Quantitative Trait Gene for Prion Disease Incubation Time in Mouse

(2008) M. O'Shea et al.   GENETICS

The prion organotypic slice culture assay—POSCA

(2008) Jeppe Falsig et al.   Nature Protocols

Polyglutamine-expanded ataxin-3 causes cerebellar dysfunction of SCA3 transgenic mice by inducing transcriptional dysregulation

(2008) An-Hsun Chou et al.   NEUROBIOLOGY OF DISEASE

The POM Monoclonals: A Comprehensive Set of Antibodies to Non-Overlapping Prion Protein Epitopes

(2008) Magdalini Polymenidou et al.   PLoS One