Assessing the causes and consequences of co-polymerization in amyloid formation

Distinct α-Synuclein Strains Differentially Promote Tau Inclusions in Neurons

(2013) Jing L. Guo et al.   CELL

The cellular prion protein traps Alzheimer's Aβ in an oligomeric form and disassembles amyloid fibers

(2013) Nadine D. Younan et al.   FASEB JOURNAL

Expanding the Repertoire of Amyloid Polymorphs by Co-polymerization of Related Protein Precursors

(2013) Claire J. Sarell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Atomic structure and hierarchical assembly of a cross-  amyloid fibril

(2013) A. W. P. Fitzpatrick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amyloid-β nanotubes are associated with prion protein-dependent synaptotoxicity

(2013) Andrew J. Nicoll et al.   Nature Communications

Direct Observation of the Interconversion of Normal and Toxic Forms of α-Synuclein

(2012) Nunilo Cremades et al.   CELL

The Amyloid State of Proteins in Human Diseases

(2012) David Eisenberg et al.   CELL

BRICHOS Domains Efficiently Delay Fibrillation of Amyloid β-Peptide

(2012) Hanna Willander et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cross-seeding effects of amyloid β-protein and α-synuclein

(2012) Kenjiro Ono et al.   JOURNAL OF NEUROCHEMISTRY

Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-β

(2012) Justin M. Nussbaum et al.   NATURE

Peptide Mixtures Can Self-Assemble into Large Amyloid Fibers of Varying Size and Morphology

(2011) Devin M. Ridgley et al.   BIOMACROMOLECULES

Structural Basis for Increased Toxicity of Pathological Aβ42:Aβ40Ratios in Alzheimer Disease

(2011) Kris Pauwels et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid-beta levels are significantly reduced and spatial memory defects are rescued in a novel neuroserpin-deficient Alzheimer’s disease transgenic mouse model

(2011) Shay Fabbro et al.   JOURNAL OF NEUROCHEMISTRY

Neuronal Production of Transthyretin in Human and Murine Alzheimer's Disease: Is It Protective?

(2011) X. Li et al.   JOURNAL OF NEUROSCIENCE

A Diversity of Assembly Mechanisms of a Generic Amyloid Fold

(2011) Timo Eichner et al.   MOLECULAR CELL

Conformational Conversion during Amyloid Formation at Atomic Resolution

(2011) Timo Eichner et al.   MOLECULAR CELL

A causative link between the structure of aberrant protein oligomers and their toxicity

(2010) Silvia Campioni et al.   Nature Chemical Biology

Structural polymorphism of Alzheimer Aβ and other amyloid fibrils

(2010) Marcus Fändrich et al.   Prion

Fibril fragmentation in amyloid assembly and cytotoxicity

(2010) Wei-Feng Xue et al.   Prion

Probing Neuroserpin Polymerization and Interaction with Amyloid-β Peptides Using Single Molecule Fluorescence

(2009) Albert Chiou et al.   BIOPHYSICAL JOURNAL

Glimpses of the molecular mechanisms of β2 -microglobulin fibril formation in vitro: Aggregation on a complex energy landscape

(2009) Geoffrey W. Platt et al.   FEBS LETTERS

Conformational Switching within Individual Amyloid Fibrils

(2009) Natallia Makarava et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β oligomers

(2009) Juha Laurén et al.   NATURE

Amyloid-β protein oligomerization and the importance of tetramers and dodecamers in the aetiology of Alzheimer's disease

(2009) Summer L. Bernstein et al.   Nature Chemistry

Structure-neurotoxicity relationships of amyloid  -protein oligomers

(2009) K. Ono et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Classification of Toxic Amyloid Oligomers

(2008) Charles G. Glabe   JOURNAL OF BIOLOGICAL CHEMISTRY

The Same Primary Structure of the Prion Protein Yields Two Distinct Self-propagating States

(2008) Natallia Makarava et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aβ(1-40) Fibril Polymorphism Implies Diverse Interaction Patterns in Amyloid Fibrils

(2008) Jessica Meinhardt et al.   JOURNAL OF MOLECULAR BIOLOGY

A regulatable switch mediates self-association in an immunoglobulin fold

(2008) Matthew F Calabrese et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mechanisms of Hybrid Oligomer Formation in the Pathogenesis of Combined Alzheimer's and Parkinson's Diseases

(2008) Igor F. Tsigelny et al.   PLoS One