Journal
PRIMARY CARE
Volume 41, Issue 2, Pages 421-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.pop.2014.02.012
Keywords
Primary care; Preventive care; Family health history; Ancestry; Genomic; Value
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This article discusses the clinical utility of genomic information for personalized preventive care of a healthy adult. Family health history is currently the most applicable genomic predictor for common, multifactorial diseases, and can also show patterns that suggest an inherited high susceptibility to a particular form of cancer or other disease. Both bloodline ancestry and shared environmental factors are important predictors for many disease states. DNA and family history analyses give information that is probabilistic, not deterministic. Therefore, family history can highlight behavioral, social, or cultural risk factors that can be modified to prevent diseases.
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