Journal
PREVENTIVE MEDICINE
Volume 51, Issue 2, Pages 118-122Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.ypmed.2010.04.016
Keywords
Metabolic syndrome; Lifestyle factor; Epidemiologic studies; Risk
Funding
- Ministry of Education, Culture, Sports, Science and Technology of Japan [13470087, 17390185, 18590594, 17790384, 20790438]
- Japan Atherosclerosis Prevention Fund
- Grants-in-Aid for Scientific Research [17790384, 17390185, 18590594, 13470087, 20790438] Funding Source: KAKEN
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Objective. To examine a combination of healthy lifestyles on the risk of metabolic syndrome (MetS) to inform future interventions. Methods. A total of 1897 men aged 35-60 years participated in an annual health check-up in 2002 and 2005. MetS was defined by AHA/NCEP criteria. Logistic regression analyses were used to estimate age- and BMI-adjusted odds ratios (ORs) of MetS incidence for each healthy lifestyle (regular physical activity, adherence to healthy eating behaviors, not current smoking, and maintaining a stable weight since one's mid-twenties), separately (Model 1) and simultaneously (Model 2). A points system was developed to derive 3-year risk of MetS incidence by assigning a specific point to each healthy lifestyle. Results. MetS developed in 285 (15.0%) subjects after the follow-up. The ORs of MetS for each healthy lifestyle ranged from 0.42 to 0.64 (Model 2). Three-year risk of MetS incidence was predicted to differ from 1% to 60% according to the individual point total of the points system. The population-attributable fraction of MetS in subjects whose point total was not in the highest quartile was 71%. Conclusion. Adherence to healthy lifestyles was associated with a lower risk of MetS among apparently healthy middle-aged Japanese male workers. (C) 2010 Elsevier Inc. All rights reserved.
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