Article
Endocrinology & Metabolism
Ambika P. Ashraf, Bhuvana Sunil, Vaneeta Bamba, Emily Breidbart, Preneet Cheema Brar, Stephanie Chung, Anshu Gupta, Aditi Khokhar, Seema Kumar, Marissa Lightbourne, Manmohan K. Kamboj, Ryan S. Miller, Nivedita Patni, Vandana Raman, Amy S. Shah, Don P. Wilson, Brenda Kohn
Summary: Pediatric endocrinologists play a crucial role in early intervention for dyslipidemia in children, with different treatment strategies needed for various cases. Timely identification and management are extremely important for preventing cardiovascular disease in at-risk youth.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Biochemistry & Molecular Biology
Virginia Esteve-Luque, Marta Fanlo-Maresma, Ariadna Padro-Miquel, Emili Corbella, Maite Rivas-Regaira, Xavier Pinto, Beatriz Candas-Estebanez
Summary: This study found that genetic risk score (GRS) is associated with the development of hypertriglyceridemia (HTG) and is significantly influenced by body mass index (BMI). This finding has important implications for the management and treatment of patients with a high genetic risk for HTG.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Jiahui Lao, Yafei Liu, Yang Yang, Peng Peng, Feifei Ma, Shuang Ji, Yujiao Chen, Fang Tang
Summary: This study analyzed the long-term and seasonal trends of dyslipidemia among the urban Chinese population, revealing significant differences in different genders and age groups. Precautionary measures should be implemented to control the elevated prevalence of dyslipidemia in specific seasons, especially during winter and traditional holidays.
LIPIDS IN HEALTH AND DISEASE
(2021)
Article
Oncology
Takatoshi Anno, Tomoki Yamatsuji, Koichi Tomoda, Shuhei Nakanishi, Hideaki Kaneto
Summary: This report presented a case of dyslipidemia induced by capecitabine in a patient with sigmoid colon cancer. The patient's dyslipidemia, characterized by markedly elevated LDL-cholesterol and unstable triglyceride levels during treatment, was ameliorated by rosuvastatin, an HMG-CoA reductase inhibitor.
FRONTIERS IN ONCOLOGY
(2021)
Review
Pharmacology & Pharmacy
Anastasios Liberis, Stamatis Petousis, Panagiotis Tsikouras
Summary: Dyslipidemia in pregnancy poses risks for both mother and fetus, with increases in LDL-C and triglyceride levels requiring monitoring. Dietary control is the primary management approach, while apheresis may be considered for severe cases. Further research on the safety of lipid-lowering agents during pregnancy is needed.
CURRENT PHARMACEUTICAL DESIGN
(2021)
Article
Biochemistry & Molecular Biology
Jianqin Zhong, Leilei Liu, Linyuan Zhang, Zixuan Xu, Lian Peng, Xiaolan Zhao, Qianyuan Yang, Tingting Yang, Degan Xu, Feng Hong
Summary: This study examines the link between urinary zinc concentration and the risk of developing dyslipidemia and its subtypes in China's ethnic minority residents. The findings suggest a non-linear relationship between urinary zinc concentration and hypertriglyceridemia and hyperbetalipoproteinemia. In certain subgroups, higher urinary zinc levels are associated with an increased risk of dyslipidemia.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2023)
Review
Endocrinology & Metabolism
Bhuvana Sunil, Christy Foster, Don P. Wilson, Ambika P. Ashraf
Summary: Landmark studies have shown that atherosclerosis begins in youth and more youth with lipid and lipoprotein disorders are being identified through screening. Existing lipid-lowering therapy for youth is safe but response may vary, indicating a need for new agents and approaches. Clinical trials on novel therapeutic agents for cholesterol and triglycerides are ongoing in youth, with a focus on altering lipid and lipoprotein metabolism.
THERAPEUTIC ADVANCES IN ENDOCRINOLOGY AND METABOLISM
(2021)
Article
Medical Laboratory Technology
Samuel Doiron, Martine Paquette, Alexis Baass, Guillaume Bollee, Heloise Cardinal, Sophie Bernard
Summary: This study investigated the association between the magnitude of proteinuria and PCSK9 concentrations. The results showed that PCSK9 was significantly elevated in patients with nephrotic syndrome and was associated with a detrimental lipid profile.
CLINICAL BIOCHEMISTRY
(2022)
Article
Endocrinology & Metabolism
Youhyun Song, Hye Sun Lee, Goeun Park, Sang-Wook Kang, Ji Won Lee
Summary: This study aimed to investigate the risk of dyslipidemia in patients with thyroid cancer (TC) compared to the general population without TC. The results showed no significant difference in dyslipidemia risk between TC patients and the general population, both in prospective and retrospective analyses.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Gastroenterology & Hepatology
Benedikt A. Aulinger, Thuan To Viet, Elisa Waldmann, Klaus G. Parhofer
Summary: The prevalence of metabolic syndrome is high in severely obese patients, reaching 78.1%, but over 20% of severely obese individuals do not have metabolic syndrome.
DIGESTIVE DISEASES
(2021)
Article
Medicine, General & Internal
Won Jung Choi, Yu Ah Hong, Ji Won Min, Eun Sil Koh, Hyung Duk Kim, Tae Hyun Ban, Young Soo Kim, Yong Kyun Kim, Seok Joon Shin, Seok Young Kim, Chul Woo Yang, Yoon-Kyung Chang
Summary: The study found that HTG is a significant risk factor for glomerulosclerosis in IgAN patients, showing a clear correlation with renal histopathological features, which is of great clinical significance.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Health Care Sciences & Services
Zunaira Ali Baig, Amir Rashid, Asifa Majeed, Zahra Masood, Asma Faryal, Zahra Arshad Khan, Aden Razaq
Summary: This study assessed lipid abnormalities in newly diagnosed diabetics and non-diabetics and found that regardless of type 2 diabetes, lipid levels can independently cause derangement, which serves as an early onset indicator rather than a later-stage complication. These derangements of lipid levels are an independent risk factor for future cardiovascular pathology.
Article
Biochemistry & Molecular Biology
Yuanlu Shu, Xiang Zhao, Changshun Yang, Yan Yan, Yao Zheng, Xijie Wang, Chengfeng Qiu
Summary: Recent evidence suggests that elevated serum PK levels are associated with the likelihood of hypercholesterolemia and hypertriglyceridemia. A nonlinear relationship between serum PK and HDL-C levels was observed. Higher levels of PK may be a risk factor for cardiovascular diseases.
LIPIDS IN HEALTH AND DISEASE
(2023)
Article
Gastroenterology & Hepatology
Anca Trifan, Cristina-Maria Muzica, Robert Nastasa, Sebastian Zenovia, Ermina Stratina, Remus Stafie, Adrian Rotaru, Ana-Maria Singeap, Camelia Cojocariu, Catalin Sfarti, Irina Girleanu, Stefan Chiriac, Tudor Cuciureanu, Laura Huiban, Carol Stanciu
Summary: Although liver cirrhosis is associated with high mortality, patients usually have a good quality of life in the compensated phase, and the disease may progress undiagnosed for many years. Vibration-controlled transient elastography with controlled attenuation parameter is a useful noninvasive tool to estimate the severity of fibrosis and steatosis. The study aimed to establish the prevalence of significant liver fibrosis diagnosed by vibration-controlled transient elastography in an apparently healthy population.
HEPATOLOGY COMMUNICATIONS
(2023)
Article
Multidisciplinary Sciences
Paula de Albuquerque, Viviani De Marco, Thiago Henrique Annibale Vendramini, Andressa Rodrigues Amaral, Sergio Catanozi, Kelly Gomes Santana, Valeria Sutti Nunes, Edna Regina Nakandakare, Marcio Antonio Brunetto
Summary: The study evaluated the therapeutic efficacy of omega-3 fatty acids associated with different fat content diets in Schnauzer with primary hyperlipidaemia. Both low-fat and moderate-fat diet combined with omega-3 fatty acids effectively reduced triglyceride and cholesterol levels without altering lipoprotein profile in Schnauzer with primary hyperlipidaemia.