Article
Agriculture, Dairy & Animal Science
Harmen P. Doekes, Henk Bovenhuis, Tom V. L. Berghof, Katrijn Peeters, Jeroen Visscher, Han A. Mulder
Summary: Resilience is the capacity of an animal to withstand disturbances and quickly recover. A study was conducted to analyze resilience indicators and natural antibodies in a purebred layer line. The findings indicate that these traits are likely controlled by multiple genes and no significant associations were found.
Article
Biochemistry & Molecular Biology
Esther J. Han, Seoung Rak Lee, Shotaro Hoshino, Mohammad R. Seyedsayamdost
Summary: Microorganisms have been a valuable source of therapeutically important natural products. This study utilized high-throughput elicitor screening to uncover cryptic metabolites with antiproliferative activity, leading to the discovery of novel bioactive compounds. These findings demonstrate the untapped potential of microbial strains in providing new molecules for cancer treatment.
ACS CHEMICAL BIOLOGY
(2022)
Article
Medicine, General & Internal
Francesca Innocenti, Vittorio Palmieri, Valerio Teodoro Stefanone, Federico D'Argenzio, Marco Cigana, Michele Montuori, Elisa Capretti, Anna De Paris, Stefano Calcagno, Irene Tassinari, Riccardo Pini
Summary: This study found that left ventricular and right ventricular dysfunction were independently associated with shock and lactate levels, and had a predictive value on patient prognosis, especially in the presence of cryptic shock.
INTERNAL AND EMERGENCY MEDICINE
(2021)
Article
Chemistry, Multidisciplinary
Yuchen Li, Seoung Rak Lee, Esther J. Han, Mohammad R. Seyedsayamdost
Summary: Natural products are important sources of pharmaceuticals and chemical tools. This study focused on the discovery of new natural products from well-studied strains, specifically targeting Streptomyces rimosus, a widely-used oxytetracycline producer. Through MALDI-MS-guided high-throughput elicitor screening (HiTES), the researchers mapped the metabolome of S. rimosus and characterized three cryptic biosynthetic gene clusters, including the unusual cyclic peptide natural product momomycin. The study demonstrated that HiTES is an effective approach for finding new chemical matter from drained strains.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Immunology
Julia Harwardt, Jan P. Bogen, Stefania C. Carrara, Michael Ulitzka, Julius Grzeschik, Bjoern Hock, Harald Kolmar
Summary: In this study, a Two-in-One antibody was identified for the first time through yeast surface display screening. The antibody can simultaneously target EGFR and PD-L1, and has a dual action by inhibiting EGFR signaling and blocking the PD-1/PD-L1 interaction. This research provides a new strategy for the development of therapeutic antibodies with novel binding properties.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Seoung Rak Lee, Mohammad R. Seyedsayamdost
Summary: This study applies an agar-based high-throughput chemical genetic screen to identify inducers of fungal biosynthetic gene clusters (BGCs) and discovers several cryptic metabolites, including a natural product with a novel scaffold. The results show that plant steroids can trigger the synthesis of this natural product and it exhibits antibiotic activity against a competitor of the fungus.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Multidisciplinary
Jong-Duk Park, Yuchen Li, Kyuho Moon, Esther J. Han, Seoung Rak Lee, Mohammad R. Seyedsayamdost
Summary: The study reports eight novel and architecturally unusual secondary metabolites synthesized by the bacterial symbiont Phaeobacter inhibens, which may originate from their algal hosts in a natural setting. Some of these metabolites exhibit potent algaecidal activity, providing important implications for the parasitic phase of algal-bacterial symbiotic interactions.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Immunology
Marco Vincenzo Lenti, Alessandro Vanoli, Emanuela Miceli, Giovanni Arpa, Michele Di Stefano, Simone Soriano, Francesca Capuano, Antonella Gentile, Nicola Aronico, Luigi Coppola, Alessandra Pasini, Ombretta Luinetti, Aurelio Mauro, Marco Paulli, Catherine Klersy, Gino Roberto Corazza, Antonio Di Sabatino
Summary: The increased infiltration of deep CD3+ IEL in the oxyntic mucosa may serve as a marker for potential autoimmune gastritis (AIG).
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Fisheries
M. S. Hollemans, G. de Vries Reilingh, S. de Vries, H. K. Parmentier, A. Lammers
Summary: The immune maturation of broiler chickens can be affected by management practices such as early life feeding strategy or sanitary conditions, but the interaction between the two has minimal impact. Early nutrition can lead to elevated levels of antibodies in the early stages, while broilers in low sanitary conditions show higher antibody levels after 14 days of age.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2021)
Article
Chemistry, Applied
Antonia Dayane Jenyffer de Farias Marques, Jerffeson de Lima Tavares, Leila Moreira de Carvalho, Thaianaly Leite Abreu, Deyse Alves Pereira, Miriane Moreira Fernandes Santos, Marta Suely Madruga, Lorena Lucena de Medeiros, Taliana Kenia Alencar Bezerra
Summary: The addition of organic coffee husk extract to chicken burgers effectively inhibits lipid oxidation without significant impact on protein oxidation. This additive is considered a potential natural additive that helps reduce agro-industrial by-products generated by the coffee industry.
Article
Food Science & Technology
Gamal Hamad, Amr Amer, Ghada Kirrella, Taha Mehany, Reham A. Elfayoumy, Rasha Elsabagh, Eman M. Elghazaly, Tuba Esatbeyoglu, Ahmed Taha, Ahmed Zeitoun
Summary: This study evaluated the presence of Staphylococcus aureus in chicken fillets and investigated the effectiveness of lyophilized seaweed extracts in inhibiting its growth. Among the seaweed extracts tested, Halimeda opuntia (HO) showed significant antibacterial activity against S. aureus. HO extract also exhibited antioxidant properties and had a higher safety threshold for consumption. Furthermore, the study demonstrated that the addition of HO extract effectively reduced S. aureus count in chicken fillets and improved sensory attributes of the meat.
Article
Agriculture, Dairy & Animal Science
Xianlu Lei, Xinxin Xu, Liqiang Liu, Hua Kuang, Liguang Xu, Chuanlai Xu
Summary: A newly developed immunochromatographic sensor is capable of rapid quantitative detection of enrofloxacin in food samples. It shows a wide detection range and high sensitivity, with stable recovery rates.
JOURNAL OF DAIRY SCIENCE
(2022)
Article
Immunology
Huiwen Wang, Ximin Zeng, Jun Lin
Summary: Egg yolk antibody IgY is emerging as a potential alternative to antibiotics for combating infectious diseases in livestock due to its cost-effectiveness, but its in vivo stability in the gastrointestinal tract is still a critical issue. Research has shown that the stability of IgY in chicken gizzard is greatly influenced by pH, with potential degradation in the acidic environment, highlighting the need for development of encapsulation methods for controlled release and protection when orally administered in livestock.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Gastroenterology & Hepatology
Marco Vincenzo Lenti, Emanuela Miceli, Alessandro Vanoli, Catherine Klersy, Gino Roberto Corazza, Antonio Di Sabatino
Summary: Approximately half of potential autoimmune gastritis patients will progress to overt autoimmune gastritis within two years, especially those with concurrent autoimmune disorders.
DIGESTIVE AND LIVER DISEASE
(2022)
Article
Multidisciplinary Sciences
Yi Yang, Yining Meng, Lina Chen, Maoli Dong, Huining Zhang, Ji Wu, Xiaoli Hao, Shuangjiang He, Yunfei Tian, Zaicheng Gong, Shaobin Shang
Summary: The successful cloning of chicken TNF-alpha and generation of corresponding antibodies provide a foundation for further study of its biological functions and detection methods.
Article
Multidisciplinary Sciences
T. V. L. Berghof, S. A. S. van der Klein, J. A. J. Arts, H. K. Parmentier, J. J. van der Poel, H. Bovenhuis
Article
Agriculture, Dairy & Animal Science
S. A. S. van der Klein, T. V. L. Berghof, J. A. J. Arts, H. K. Parmentier, J. J. van der Poel, H. Bovenhuis
Article
Immunology
T. V. L. Berghof, J. A. J. Arts, H. Bovenhuis, A. Lammers, J. J. van der Poel, H. K. Parmentier
Article
Immunology
Tom V. L. Berghof, Marleen H. P. W. Visker, Joop A. J. Arts, Henk K. Parmentier, Jan J. van der Poel, Addie L. J. Vereijken, Henk Bovenhuis
FRONTIERS IN IMMUNOLOGY
(2018)
Article
Agriculture, Dairy & Animal Science
T. V. L. Berghof, H. T. L. Lai, A. Lammers, G. de Vries Reilingh, M. G. B. Nieuwland, A. J. A. Aarnink, H. K. Parmentier
Review
Agriculture, Dairy & Animal Science
T. V. L. Berghof, H. K. Parmentier, A. Lammers
Article
Genetics & Heredity
Tom V. L. Berghof, Marieke Poppe, Han A. Mulder
FRONTIERS IN GENETICS
(2019)
Article
Fisheries
T. V. L. Berghof, M. G. R. Matthijs, J. A. J. Arts, H. Bovenhuis, R. M. Dwars, J. J. van der Poel, M. H. P. W. Visker, H. K. Parmentier
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2019)
Article
Biology
Asmoro Lelono, Diana A. Robledo-Ruiz, Tom V. L. Berghof, Henk K. Parmentier, Bernd Riedstra, Ton G. Groothuis
Article
Genetics & Heredity
Tom V. L. Berghof, Henk Bovenhuis, Han A. Mulder
FRONTIERS IN GENETICS
(2019)
Article
Agriculture, Dairy & Animal Science
Harmen P. Doekes, Henk Bovenhuis, Tom V. L. Berghof, Katrijn Peeters, Jeroen Visscher, Han A. Mulder
Summary: Resilience is the capacity of an animal to withstand disturbances and quickly recover. A study was conducted to analyze resilience indicators and natural antibodies in a purebred layer line. The findings indicate that these traits are likely controlled by multiple genes and no significant associations were found.
Article
Agriculture, Dairy & Animal Science
Jesper Tessin, Judith Rohde, Arne Jung, Nicole Kemper, Jochen Schulz
Summary: In this study, samples from poultry house environment and culled birds were collected, and E. cecorum was successfully isolated. The principle of isolating the pathogen by streaking on a chromogenic agar may motivate researchers to investigate transmission routes and optimize biosecurity measures.
Article
Agriculture, Dairy & Animal Science
Junqin Zhang, Zimin Xie, Yanlin Pan, Zuoxin Chen, Yunzhen Huang, Linlin Li, Jiawen Dong, Yong Xiang, Qi Zhai, Minhua Sun, Xingying Li, Shujian Huang, Ming Liao
Summary: In recent years, there has been an increase in the occurrence of fowl adenovirus 2 (FAdV-2) in China, posing a significant threat to the poultry industry. This study investigated the epidemiology, phylogenetic relationship, genomic characteristics, and pathogenicity of FAdV-2. The results showed that FAdV-2 was the most commonly detected serotype among various FAdV serotypes. Genetic analysis revealed that these FAdV-2 strains formed a distinct branch within the FAdV-D group and had a high nucleotide similarity with reference strains. Recombination analysis identified recombination events between FAdV-2 and FAdV-11 in some strains. Pathogenicity experiments demonstrated that a recombinant FAdV-2 strain caused a high mortality rate and more severe disease in chickens. These findings contribute to our understanding of FAdV-2 and provide a basis for vaccine development.
Article
Agriculture, Dairy & Animal Science
Ebtsam Iraqi, Ali Abdel Hady, Nadia Elsayed, Hanaa Khalil, Amina El-Saadany, Karim El-Sabrout
Summary: Thermal manipulation during egg incubation, particularly at 12 to 18 days, has positive effects on embryonic development, hatching characteristics, chick quality, as well as posthatch thermotolerance and performance.
Article
Agriculture, Dairy & Animal Science
Yong Liu, Mingxin Song, He Bai, Chunhua Wang, Fei Wang, Qi Yuan
Summary: Dietary curcumin supplementation can significantly improve egg quality of quails in the late laying period, primarily by improving lipid metabolism and selectively regulating the intestinal microbial community.
Article
Agriculture, Dairy & Animal Science
Lei Zhang, Zhixuan Song, Peiyao Li, Xingju Song, Xinming Tang, Dandan Hu
Summary: This study evaluated the vaccine potential of recombinant proteins for avian coccidiosis caused by Eimeria. The results showed that the rEten5-B protein can trigger immune protection against E. tenella and may be a potential and effective subunit vaccine for the control of coccidiosis in poultry.
Article
Agriculture, Dairy & Animal Science
Milan Kumar Sharma, Amit Kumar Singh, Doyun Goo, Venkata Sesha Reddy Choppa, Hanseo Ko, Hanyi Shi, Woo Kyun Kim
Summary: The study investigates the effect of Eimeria infection on gastrointestinal physiology, growth performance, and egg production of Hy-Line W-36 laying hens during peak production. Results show that Eimeria infection negatively affects body weight, feed intake, immune response, and nutrient transporter gene expression. Egg production temporarily ceases in hens infected with high and medium-high dosages of Eimeria.
Article
Agriculture, Dairy & Animal Science
Elwy A. Ashour, Mahmoud Kamal, Hayman A. A. Altaie, Ayman A. Swelum, Gamaleldin M. Suliman, Guillermo Tellez-Isaias, Mohamed E. Abd El-Hack
Summary: This study evaluated the effects of CP and ME on the performance and nutritional value of Japanese quail lay chicken. The results showed that protein and energy levels significantly influenced all productive outcomes except feed conversion ratio. The combination of dietary energy and protein levels had a substantial effect on all egg quality trials evaluated. It is recommended to feed layer Japanese quail between the ages of 8 and 20 weeks during the summer with a dietary energy content of 2,900 kcal ME/kg and 20% CP.
Article
Agriculture, Dairy & Animal Science
J. E. Doornweerd, R. F. Veerkamp, B. de Klerk, M. van der Sluis, A. C. Bouwman, E. D. Ellen, G. Kootstra
Summary: Tracking group-housed individual broilers using video can provide valuable information on their health, welfare, and performance. This study conducted a comprehensive analysis on broiler tracking on video and potential tracking errors, highlighting the potential and challenges of phenotyping broiler locomotion. The results emphasized the importance of addressing tracking errors, potential algorithm improvements, and the need for an external animal identification system for efficient locomotion phenotyping.
Article
Agriculture, Dairy & Animal Science
Jiayu Wu, Yanan Wang, Yu An, Changyu Tian, Lingfeng Wang, Zuhong Liu, Desheng Qi
Summary: This study compared the gene expression differences in liver tissues of laying hens at different ages using RNA sequencing, and found that the transport and metabolism of amino acids changed during the growing period, which influenced the growth and development of the hens.
Article
Agriculture, Dairy & Animal Science
J. Raabe, G. Raveendran, W. Otten, K. Homeyer, T. Bartels
Summary: This study investigated the effects of different flicker frequencies on the behavior, performance, and stress response in male turkeys. The results showed that flicker frequencies of 165 Hz or higher had no detrimental effect on growth performance, injurious pecking, or endocrine stress response in the turkeys.
Article
Agriculture, Dairy & Animal Science
Adamu Mani Isa, Yanyan Sun, Yuanmei Wang, Yunlei Li, Jingwei Yuan, Aixin Ni, Hui Ma, Lei Shi, Hailai Hagos Tesfay, Yunhe Zong, Panlin Wang, Pingzhuang Ge, Jilan Chen
Summary: This study sequenced mRNAs and lncRNAs in the ovary stroma of specific chicken breeds and their reciprocal crossbreds to understand the molecular mechanism of heterosis for egg production. Results showed that genes with nonadditive expression were related to follicle growth and atresia as well as oxidative stress in the crossbred hens.
Article
Agriculture, Dairy & Animal Science
Zhepeng Wang, Qiu Chen, Yiwei Wang, Yulu Wang, Ruifang Liu
Summary: The study investigates the functional variants associated with chicken eggshell color in the SLCO1B3 gene by measuring the eggshell color of Lueyang black-boned chickens and analyzing the genetic data. It identifies 15 variants in SLCO1B3 that are significantly associated with eggshell color. However, the functional analysis shows that one specific variant, 1B3_SNP108, does not have a significant effect on promoter activity. This study highlights the importance of SLCO1B3 and its variants in breeding eggshell color.
Article
Agriculture, Dairy & Animal Science
P. Yin, Q. Tong, B. M. Li, W. C. Zheng, Y. Wang, H. Q. Peng, X. L. Xue, S. Q. Wei
Summary: This study investigated the welfare and health of laying hens in a multitier system. The results showed that the spatial distribution of hens changed with increasing age, and lower-ranking hens preferred to stay in lower tiers to avoid competition but still had access to resources. This improved the welfare and health of the hens near the end of the laying cycle.
Article
Agriculture, Dairy & Animal Science
Wenwen Liang, Siqiong Jie, Yiqin Wang, Xiaowei Wen, Yanling Xiong, Xiaoxi Lin, Zhengrong Lv
Summary: This study examined the effect of risk perceptions on preventive behavior among vendors in the live poultry wholesale market and the live poultry retail market in Guangdong Province using the health belief model and structural equation modeling. The results showed that perceived severity and perceived benefits positively influenced vendors' self-efficacy in the wholesale market, while perceived barriers negatively affected self-efficacy in both the wholesale and retail markets. Moreover, cues to action mediated the relationship between perceived severity, perceived benefits, and self-efficacy, and also mediated the effect of perceived susceptibility among wholesale market vendors.
Article
Agriculture, Dairy & Animal Science
Shreeya Sharma, Raveendra R. Kulkarni, Shayan Sharif, Hosni Hassan, Mohammadali Alizadeh, Scott Pratt, Khaled Abdelaziz
Summary: The study investigates the impact of exposing chick embryos to antigens via in ovo delivery of poultry-specific lactobacilli on the expression of genes associated with early bursal development and maturation. Results indicate that the supplementation of poultry-specific lactobacilli to chick embryos can accelerate the development and immunological maturation of the bursa of Fabricius.