Article
Agriculture, Dairy & Animal Science
Islam I. Omara, Chasity M. Pender, Mallory B. White, Rami A. Dalloul
Summary: This study evaluated the impact of yeast-derived beta-glucan supplementation on the expression of immune response genes in commercial broiler chickens during an Eimeria challenge. The results showed that dietary beta-glucan enhanced and modulated the expression of immune response genes in the spleen, thymus, and bursa of broiler chickens during coccidiosis, indicating its potential as a feed additive for improving immune response in poultry.
Article
Agriculture, Dairy & Animal Science
Michel B. Verwoolde, Jurgen van Baa, Christine A. Jansen, Elisabeth A. M. Graat, David M. Lamot, Aart Lammers, Lieske van Eck
Summary: This study is the first to investigate the impact of stimulating the maternal innate immune system with lipopolysaccharides (LPS) or beta-glucan on growth performance and immune responses in the next generation. The findings show that offspring of LPS-treated broiler breeders have higher feed efficiency post-NE challenge, with more intestinal lesions observed. Additionally, both LPS and beta-glucan maternal treatments resulted in transgenerational effects on blood-derived monocytes, indicating a potential impact on immune responsiveness in the offspring.
Article
Immunology
Carissa Gaghan, Daniel Adams, Javid Mohammed, Rocio Crespo, Kimberly Livingston, Raveendra R. Kulkarni
Summary: This study investigated the protective immune mechanisms induced by a commercial broiler vaccine against the enteric disease coccidiosis. The results showed that the vaccine reduced oocyst shedding and increased the expression of immune genes in spleen and cecal tonsils. The vaccination also led to increased frequencies of macrophages and activated T cells in these lymphoid tissues.
Article
Veterinary Sciences
Kashif Hussain, Asghar Abbas, Hamdan Attia H. Alanazi, Abdulrahman Mohammed A. Alharbi, Ahmad Abdulrahman Alaiiri, Atif Rehman, Muhammad Umair Waqas, Muhammad Asif Raza, Riffat Yasin, Baseer Ahmad, Naheed Bano, Hafeez Ur Rehman Ali Khera
Summary: The study investigated the immunomodulatory effects of Artemisia brevifolia leaf extract on coccidiosis in broiler chickens. 175 day-old chicks were divided into 5 groups and infected with mixed Eimeria oocysts. The extract was orally administered to three groups at different doses. Cellular and humoral immunity were enhanced by the extract, with the highest dose showing the strongest immunomodulatory effect.
PAKISTAN VETERINARY JOURNAL
(2023)
Article
Veterinary Sciences
Ahmed Ali Moryani, Nasir Rajput, Muhammad Naeem, Atta Hussain Shah, Ali Raza Jahejo
Summary: The study evaluated the effectiveness of herbs on the health and immunity of broiler chickens challenged with coccidiosis. It was found that a mixture of herbs significantly improved survival rates, intestinal histomorphology, blood parameters, and bacteria levels in the challenged chickens. Additionally, the mRNA expression of immunity-related toll-like receptors was regulated by the herb mixture, leading to better immunity.
PAKISTAN VETERINARY JOURNAL
(2021)
Article
Chemistry, Multidisciplinary
Zhaoxia Chen, Tuying Yong, Zhaohan Wei, Xiaoqiong Zhang, Xin Li, Jiaqi Qin, Jianye Li, Jun Hu, Xiangliang Yang, Lu Gan
Summary: This study developed a personalized cancer vaccine by engineering inactivated probiotic Escherichia coli Nissle 1917 to load tumor antigens and beta-glucan, a trained immunity inducer. The vaccine efficiently integrates trained immunity and adaptive immunity, generating strong prophylactic and therapeutic effects to inhibit tumor growth. It also prevents postoperative tumor recurrence by delivering autologous tumor antigens.
Article
Medicine, Research & Experimental
Yuchen Pan, Jingman Li, Xiaoyu Xia, Jiali Wang, Qi Jiang, Jingjing Yang, Huan Dou, Huaping Liang, Kuanyu Li, Yayi Hou
Summary: In this study, BSNPs nanoparticles were successfully synthesized and shown to effectively reprogram macrophages to enhance trained immunity. BSNPs protected mice against sepsis and secondary infections caused by Escherichia coli. The study also revealed the signaling and regulatory mechanisms of BSNP-induced trained immunity, which were found to be mTOR-dependent.
Article
Agriculture, Dairy & Animal Science
Rafael Humberto de Carvalho, Marco Aurelio Callegari, Cleandro Pazinato Dias, Susanne Kirwan, Mara Cristina Ribeiro da Costa, Caio Abercio da Silva
Summary: Supplementing the diet of sows with beta G-(1,3) derived from Euglena gracilis algae results in increased colostrum production and consumption, as well as improved weight gain in piglets during the first 18 hours after birth. The colostrum produced by the sows and the blood serum of the piglets also exhibit higher concentrations of immunoglobulins.
Review
Immunology
Mengyan Wang, Zhongdong Zhang, Xiaotian Dong, Biao Zhu
Summary: Beta-glucan, the most abundant polysaccharide in the cell wall of Pneumocystis jirovecii, has unique immunobiological characteristics and binds to various cell surface receptors to produce an inflammatory response and immune effects. Understanding how Pneumocystis beta-glucan recognizes its receptors, activates signaling pathways, and regulates immunity is important for developing new therapies against Pneumocystis.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Agriculture, Dairy & Animal Science
R. R. Santos, F. C. Velkers, J. C. M. Vernooij, L. Star, J. L. T. Heerkens, J. van Harn, I. C. de Jong
Summary: Different combinations of gut health-promoting dietary interventions were tested to support broilers during different stages of Eimeria infection. The best feed conversion ratio, as well as lower oocyst output and lesion scores, were observed in broilers that received multispecies probiotics, saponins, artemisin, curcumin, coated butyrate and threonine.
Article
Biotechnology & Applied Microbiology
Duo Li, Weiran Li, Peng Zheng, Ying Yang, Qingwen Liu, Yongmao Hu, Jinrong He, Qiong Long, Yanbing Ma
Summary: This study investigates the benefits of inducing trained immunity in promoting antitumor adaptive immune responses using a tumor vaccine. A biphasic delivery system was developed to deliver immune inducers and specific tumor antigens effectively. The nanovaccine formulation demonstrated targeted delivery and enhanced immune responses. Immunization with the nanovaccine completely inhibited tumor growth and even eradicated established tumors in mice. The controlled release and targeted delivery of antigen and trained immunity inducers with an NP/hydrogel biphasic system provide a promising strategy for tumor vaccination.
JOURNAL OF NANOBIOTECHNOLOGY
(2023)
Article
Agriculture, Dairy & Animal Science
Maged M. Mahmoud, Ahmed M. Al-Hejin, Turki S. Abujamel, Aly M. Ghetas, Haitham A. Yacoub
Summary: The current study investigated the potential use of avian beta-defensin-1 peptide as a candidate agent against coccidiosis infection in broiler chickens. In-silico analysis was employed to study the structure of the peptide and its mode of action. The results showed that treatment with beta-defensin-1 peptide led to a significant reduction in oocyst count and down-regulation of beta-defensin 1 and 4 expression. These findings may contribute to the development of novel approaches for coccidiosis control in broilers.
ANIMAL BIOTECHNOLOGY
(2022)
Article
Fisheries
Michel B. Verwoolde, Robin H. G. A. van den Biggelaar, Ger de Vries Reilingh, Joop A. J. Arts, Jurgen van Baal, Aart Lammers, Christine A. Jansen
Summary: The study showed that monocytes from different genetic backgrounds can be trained, but there are differences in immune functionality associated with innate training between layers and broilers. These differences may have an impact on disease resistance, though further research is needed to elucidate this.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2021)
Article
Immunology
Hui Liang, Yu Li, Ming Li, Wei Zhou, Jie Chen, Zhen Zhang, Yalin Yang, Chao Ran, Zhigang Zhou
Summary: Beta-glucan can enhance the resistance of zebrafish against spring viraemia of carp virus (SVCV) by stimulating the type I interferon (IFN) antiviral immune response.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Immunology
Yuexing Zhang, Mingyu Guo, Ning Li, Zhiyong Dong, Linwei Cai, Bowen Wu, Jianjun Xie, Liang Liu, Lina Ren, Bo Shi
Summary: This study evaluated the effects of beta-glucan on largemouth bass, revealing its potential to enhance the fish's resistance to Aeromonas schubertii and influence intestinal health and microbiota.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Tom Dale, Michael R. Bedford, Gregory A. Tucker, John M. Brameld, Tim Parr
Summary: This study found that fibrolytic enzymes have some specificity for certain cereals in terms of the degradation products and generation of xylooligosaccharides (XOS) and monosaccharides. Optimizing enzyme combinations based on cereal types may help maximize feed efficiency in livestock.
ANIMAL FEED SCIENCE AND TECHNOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Tom Dale, Michael R. Bedford, Julie King, Gregory A. Tucker, John M. Brameld, Tim Parr
Summary: This study investigated the efficacy of different enzyme-wheat variety combinations and found that fibrolytic enzymes have different effects on various wheat varieties. These findings suggest the possibility of optimizing the combination of wheat variety and enzyme in animal feeds to improve feed efficiency in livestock.
ANIMAL FEED SCIENCE AND TECHNOLOGY
(2023)
Article
Agriculture, Dairy & Animal Science
L. S. David, M. R. Abdollahi, M. R. Bedford, V. Ravindran
Summary: An experiment was conducted to determine the digestible calcium and phosphorus requirements of broiler chickens. The results showed that a combination of 3.5 g/kg digestible phosphorus and 3.0-3.5 g/kg digestible calcium resulted in optimal weight gain and tibia ash. This study provides important guidance for the nutrition and formulation of diets for broiler chickens.
Article
Agriculture, Dairy & Animal Science
Ashraf Alkhtib, Philippe Wilson, Mike R. Bedford, Helen Nell Masey O'Neill, Emily Burton
Summary: This systematic review investigates the relevance of existing life cycle analysis (LCA) and environmental assessment studies in informing sustainable poultry meat production strategies. A Rapid Evidence Assessment (REA) was conducted on articles published from 2000 to 2020, covering LCA studies on meat poultry strains, poultry manure emission, and environmental assessments of plant-based feed ingredients. The review found that there is a lack of reliable in vivo data to support the use of existing studies for guiding nutritional strategies and poultry meat production.
Article
Immunology
Anisha M. Thanki, Steven Hooton, Natasha Whenham, Michael G. Salter, Mike R. Bedford, Helen V. Masey O'Neill, Martha R. J. Clokie
Summary: This study showed that adding a phage cocktail to chicken feed effectively reduced Salmonella colonization in chickens, with the optimal dose of phage being 10(5) PFU/day. By the end of the study, no Salmonella was detected in the group that received phage at this dose. Phage treatment also improved the growth performance of challenged birds.
EMERGING MICROBES & INFECTIONS
(2023)
Article
Agriculture, Dairy & Animal Science
Clay J. Maynard, Craig W. Maynard, Garrett J. Mullenix, Alison Ramser, Elizabeth S. Greene, Mike R. Bedford, Sami Dridi
Summary: This study investigated the effect of heat stress and exogenous phytase supplementation on growth performance, muscle myopathy incidence, and meat quality in broilers. Heat stress significantly affected body temperature, feed intake, body weight, water intake, blood parameters, and meat quality. Exogenous phytase supplementation improved growth performance and reduced muscle myopathy incidence under normal temperature conditions, but increased muscle myopathy incidence under heat stress conditions.
Review
Agriculture, Dairy & Animal Science
Laura Shiromi David, M. Naveed Anwar, M. Reza Abdollahi, Michael R. Bedford, Velmurugu Ravindran
Summary: Calcium is crucial for poultry nutrition, but the current concern is the oversupply of calcium rather than a deficiency. Recent changes in feed formulas have prompted closer examination of digestible calcium, as it is interrelated with phosphorus absorption and utilization. Data on the digestibility of calcium and phosphorus in feed ingredients have been determined, and preliminary data on the requirements for different growth stages of broilers have become available. This review focuses on these recent advances in calcium nutrition, as well as homeostatic control mechanisms, different calcium sources, and factors influencing calcium digestibility in poultry.
Article
Agriculture, Dairy & Animal Science
H. K. Zanu, M. Iddrisu, B. G. Fosu, H. K. Ketemepi, M. R. Bedford
Summary: High phytic acid and fine oyster shell particle size improve growth performance of broilers, while low phytic acid and coarse oyster shell particle size promote bone health.
BRITISH POULTRY SCIENCE
(2023)
Article
Multidisciplinary Sciences
Colleen R. Sprigg, Philip T. A. Leftwich, Emily Burton, Dawn Scholey, Michael R. Bedford, Charles A. Brearley
Summary: Inert digestibility index markers like titanium dioxide are commonly used in poultry feeding trials. However, the use of titanium dioxide in cell biology for enrichment of inositol phosphates suggests that its use as an inert marker may not be as inert as assumed. Our experiment showed no significant difference in the effect of phytase inclusion in the presence or absence of titanium dioxide, indicating that its inclusion in feed does not interfere with the recovery of inositol phosphates from digesta samples.
Article
Agriculture, Dairy & Animal Science
A. Simic, G. Gonzalez-Ortiz, S. C. Mansbridge, S. P. Rose, M. R. Bedford, D. Yovchev, V. R. Pirgozliev
Summary: A study was conducted to investigate the effects of dietary fiber, xylanase, xylooligosaccharides, and their combination on chicken growth performance and nutrient utilization. The results showed that the combination of xylanase and xylooligosaccharides improved feed conversion efficiency and weight gain, while the inclusion of dietary fiber had negative effects on nutrient utilization. Additionally, the addition of dietary fiber increased the concentration of short-chain fatty acids in the cecum.
Article
Agriculture, Dairy & Animal Science
Mohammad Houshyar, Ali Asghar Saki, Mohammad Yousef Alikhani, Michael Richard Bedford, Meysam Soleimani, Farideh Kamarehei
Summary: This study evaluated the effects of a laboratory 3-phytase and a commercial 6-phytase, alone and in combination, on broilers. The addition of Lab-Phy increased the phosphorus and calcium content in the tibia, while Com-Phy alone and in combination with Lab-Phy further increased the phosphorus and calcium content. The expression of NaPi-IIb in the duodenum was influenced by the reduction of nonphytate phosphorus and the addition of phytase. Broilers fed the negative control diet had the lowest body weight, villi characteristics, Newcastle disease antibody titer, and nutrient digestibility. Supplementation with phytases improved growth performance, intestinal characteristics, immune response, and nutrient digestibility in broilers receiving the negative control diet.
Article
Agriculture, Dairy & Animal Science
I. M. Whiting, V. Pirgozliev, M. R. Bedford
Summary: The present study aimed to determine the xylan fractions of 10 wheat cultivars and their response to treatment by the same commercial xylanase enzyme preparation. Information obtained was used to select 5 wheats for a feeding experiment to predict the feeding value based on the rate of xylan release. Treatment with the same enzyme resulted in varying levels of hydrolysis, and the addition of xylanase improved weight gain and feed conversion ratio.
Review
Agriculture, Dairy & Animal Science
Edwin T. Moran, Michael R. Bedford
Summary: Endogenous protein leaving the ileum largely consists of accrued mucins from the upper gastrointestinal tract (GIT) that had resisted digestion. The amounts released rely on their mucosal generation during enteral feeding which vary with age as well as diet. These digestion resistant proteins of endogenous origin continue to be unavailable in the large intestine, whereas those of dietary origin provide amino acids that largely support the existing microbial population while denying limited amounts for absorption.
Article
Agriculture, Dairy & Animal Science
An Bautil, Michael R. Bedford, Johan Buyse, Christophe M. Courtin
Summary: This study aimed to evaluate the potential of reduced-particle size wheat bran and endoxylanases as feed additives in stimulating arabinoxylan hydrolysis and fermentation in young broilers. The results showed that the addition of endoxylanase increased arabinoxylan solubilization and fermentation. Adding reduced-particle size wheat bran improved the utilization of wheat arabinoxylan. However, at 28 days, the addition of reduced-particle size wheat bran reduced body weight gain but increased butyric acid concentrations.
Article
Agriculture, Dairy & Animal Science
Namalika D. Karunaratne, Henry L. Classen, Andrew G. van Kessel, Michael R. Bedford, Nancy P. Ames, Rex W. Newkirk
Summary: The objective of this study was to evaluate the effects of diet medication and beta-glucanase on digesta soluble beta-glucan depolymerization, carbohydrate fermentation, and performance of coccidiosis-vaccinated broiler chickens. The results showed that beta-glucanase reduced the molecular weight of beta-glucan, decreased ileal viscosity, and reduced the concentration of short-chain fatty acids, while diet medication had minimal effects on carbohydrate fermentation.
Article
Agriculture, Dairy & Animal Science
Jesper Tessin, Judith Rohde, Arne Jung, Nicole Kemper, Jochen Schulz
Summary: In this study, samples from poultry house environment and culled birds were collected, and E. cecorum was successfully isolated. The principle of isolating the pathogen by streaking on a chromogenic agar may motivate researchers to investigate transmission routes and optimize biosecurity measures.
Article
Agriculture, Dairy & Animal Science
Junqin Zhang, Zimin Xie, Yanlin Pan, Zuoxin Chen, Yunzhen Huang, Linlin Li, Jiawen Dong, Yong Xiang, Qi Zhai, Minhua Sun, Xingying Li, Shujian Huang, Ming Liao
Summary: In recent years, there has been an increase in the occurrence of fowl adenovirus 2 (FAdV-2) in China, posing a significant threat to the poultry industry. This study investigated the epidemiology, phylogenetic relationship, genomic characteristics, and pathogenicity of FAdV-2. The results showed that FAdV-2 was the most commonly detected serotype among various FAdV serotypes. Genetic analysis revealed that these FAdV-2 strains formed a distinct branch within the FAdV-D group and had a high nucleotide similarity with reference strains. Recombination analysis identified recombination events between FAdV-2 and FAdV-11 in some strains. Pathogenicity experiments demonstrated that a recombinant FAdV-2 strain caused a high mortality rate and more severe disease in chickens. These findings contribute to our understanding of FAdV-2 and provide a basis for vaccine development.
Article
Agriculture, Dairy & Animal Science
Ebtsam Iraqi, Ali Abdel Hady, Nadia Elsayed, Hanaa Khalil, Amina El-Saadany, Karim El-Sabrout
Summary: Thermal manipulation during egg incubation, particularly at 12 to 18 days, has positive effects on embryonic development, hatching characteristics, chick quality, as well as posthatch thermotolerance and performance.
Article
Agriculture, Dairy & Animal Science
Yong Liu, Mingxin Song, He Bai, Chunhua Wang, Fei Wang, Qi Yuan
Summary: Dietary curcumin supplementation can significantly improve egg quality of quails in the late laying period, primarily by improving lipid metabolism and selectively regulating the intestinal microbial community.
Article
Agriculture, Dairy & Animal Science
Lei Zhang, Zhixuan Song, Peiyao Li, Xingju Song, Xinming Tang, Dandan Hu
Summary: This study evaluated the vaccine potential of recombinant proteins for avian coccidiosis caused by Eimeria. The results showed that the rEten5-B protein can trigger immune protection against E. tenella and may be a potential and effective subunit vaccine for the control of coccidiosis in poultry.
Article
Agriculture, Dairy & Animal Science
Milan Kumar Sharma, Amit Kumar Singh, Doyun Goo, Venkata Sesha Reddy Choppa, Hanseo Ko, Hanyi Shi, Woo Kyun Kim
Summary: The study investigates the effect of Eimeria infection on gastrointestinal physiology, growth performance, and egg production of Hy-Line W-36 laying hens during peak production. Results show that Eimeria infection negatively affects body weight, feed intake, immune response, and nutrient transporter gene expression. Egg production temporarily ceases in hens infected with high and medium-high dosages of Eimeria.
Article
Agriculture, Dairy & Animal Science
Elwy A. Ashour, Mahmoud Kamal, Hayman A. A. Altaie, Ayman A. Swelum, Gamaleldin M. Suliman, Guillermo Tellez-Isaias, Mohamed E. Abd El-Hack
Summary: This study evaluated the effects of CP and ME on the performance and nutritional value of Japanese quail lay chicken. The results showed that protein and energy levels significantly influenced all productive outcomes except feed conversion ratio. The combination of dietary energy and protein levels had a substantial effect on all egg quality trials evaluated. It is recommended to feed layer Japanese quail between the ages of 8 and 20 weeks during the summer with a dietary energy content of 2,900 kcal ME/kg and 20% CP.
Article
Agriculture, Dairy & Animal Science
J. E. Doornweerd, R. F. Veerkamp, B. de Klerk, M. van der Sluis, A. C. Bouwman, E. D. Ellen, G. Kootstra
Summary: Tracking group-housed individual broilers using video can provide valuable information on their health, welfare, and performance. This study conducted a comprehensive analysis on broiler tracking on video and potential tracking errors, highlighting the potential and challenges of phenotyping broiler locomotion. The results emphasized the importance of addressing tracking errors, potential algorithm improvements, and the need for an external animal identification system for efficient locomotion phenotyping.
Article
Agriculture, Dairy & Animal Science
Jiayu Wu, Yanan Wang, Yu An, Changyu Tian, Lingfeng Wang, Zuhong Liu, Desheng Qi
Summary: This study compared the gene expression differences in liver tissues of laying hens at different ages using RNA sequencing, and found that the transport and metabolism of amino acids changed during the growing period, which influenced the growth and development of the hens.
Article
Agriculture, Dairy & Animal Science
J. Raabe, G. Raveendran, W. Otten, K. Homeyer, T. Bartels
Summary: This study investigated the effects of different flicker frequencies on the behavior, performance, and stress response in male turkeys. The results showed that flicker frequencies of 165 Hz or higher had no detrimental effect on growth performance, injurious pecking, or endocrine stress response in the turkeys.
Article
Agriculture, Dairy & Animal Science
Adamu Mani Isa, Yanyan Sun, Yuanmei Wang, Yunlei Li, Jingwei Yuan, Aixin Ni, Hui Ma, Lei Shi, Hailai Hagos Tesfay, Yunhe Zong, Panlin Wang, Pingzhuang Ge, Jilan Chen
Summary: This study sequenced mRNAs and lncRNAs in the ovary stroma of specific chicken breeds and their reciprocal crossbreds to understand the molecular mechanism of heterosis for egg production. Results showed that genes with nonadditive expression were related to follicle growth and atresia as well as oxidative stress in the crossbred hens.
Article
Agriculture, Dairy & Animal Science
Zhepeng Wang, Qiu Chen, Yiwei Wang, Yulu Wang, Ruifang Liu
Summary: The study investigates the functional variants associated with chicken eggshell color in the SLCO1B3 gene by measuring the eggshell color of Lueyang black-boned chickens and analyzing the genetic data. It identifies 15 variants in SLCO1B3 that are significantly associated with eggshell color. However, the functional analysis shows that one specific variant, 1B3_SNP108, does not have a significant effect on promoter activity. This study highlights the importance of SLCO1B3 and its variants in breeding eggshell color.
Article
Agriculture, Dairy & Animal Science
P. Yin, Q. Tong, B. M. Li, W. C. Zheng, Y. Wang, H. Q. Peng, X. L. Xue, S. Q. Wei
Summary: This study investigated the welfare and health of laying hens in a multitier system. The results showed that the spatial distribution of hens changed with increasing age, and lower-ranking hens preferred to stay in lower tiers to avoid competition but still had access to resources. This improved the welfare and health of the hens near the end of the laying cycle.
Article
Agriculture, Dairy & Animal Science
Wenwen Liang, Siqiong Jie, Yiqin Wang, Xiaowei Wen, Yanling Xiong, Xiaoxi Lin, Zhengrong Lv
Summary: This study examined the effect of risk perceptions on preventive behavior among vendors in the live poultry wholesale market and the live poultry retail market in Guangdong Province using the health belief model and structural equation modeling. The results showed that perceived severity and perceived benefits positively influenced vendors' self-efficacy in the wholesale market, while perceived barriers negatively affected self-efficacy in both the wholesale and retail markets. Moreover, cues to action mediated the relationship between perceived severity, perceived benefits, and self-efficacy, and also mediated the effect of perceived susceptibility among wholesale market vendors.
Article
Agriculture, Dairy & Animal Science
Shreeya Sharma, Raveendra R. Kulkarni, Shayan Sharif, Hosni Hassan, Mohammadali Alizadeh, Scott Pratt, Khaled Abdelaziz
Summary: The study investigates the impact of exposing chick embryos to antigens via in ovo delivery of poultry-specific lactobacilli on the expression of genes associated with early bursal development and maturation. Results indicate that the supplementation of poultry-specific lactobacilli to chick embryos can accelerate the development and immunological maturation of the bursa of Fabricius.