Journal
POSTGRADUATE MEDICINE
Volume 125, Issue 5, Pages 139-141Publisher
JTE MULTIMEDIA
DOI: 10.3810/pgm.2013.09.2696
Keywords
asterixis; subcortical myoclonus; negative myoclonus; gabapeptin
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Asterixis has been reported as a side effect of toxic and metabolic abnormalities. The current literature contains very little evidence of gabapentin-related neurotoxicity. Our observations reveal that neurotoxic side effects of gabapentin use may be seen even when dose adjustments are made for patients with mild-to-moderate renal dysfunction. Clinical vigilance for possible neurotoxic effects of gabapentin therapy in patients with renal dysfunction is warranted.
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