Journal
POLYMER-PLASTICS TECHNOLOGY AND ENGINEERING
Volume 54, Issue 6, Pages 573-580Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/03602559.2014.974186
Keywords
Chitosan; Gentamycin sulphate; Glycerol; Poly vinyl pyrolidone; Poly (N-isopropyl acrylamide)
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Funding
- University Grant Commission
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Developments in the field of polymer science have led us to the development of Chitosan and PNIPAm mixed pH and temperature responsive hydrogel films. Characterizations were done by Swelling analysis, FTIR, DSC, FESEM and Antibacterial assay. Optimized hydrogel film on swelling analysis does not lose its shape and was not dissolve in to the different buffer solution and at different temperature. FTIR, DSC and FESEM study confirmed the changes in to the hydrogel film after drug absorption. On increasing the temperature and change in pH of the solution, drug absorption increased which was confirmed by zone of inhibition against E. coli.
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