Article
Chemistry, Applied
Xiaolian Niu, Longfei Wang, Mengjie Xu, Miao Qin, Liqin Zhao, Yan Wei, Yinchun Hu, Xiaojie Lian, Ziwei Liang, Song Chen, Weiyi Chen, Di Huang
Summary: The novel PA6/CS@n-HA/PA6 bilayered tissue guided membranes show good physical and mechanical properties, biological compatibility, and osteoconductivity. Through a series of tests, it is confirmed that the membranes have good porosity and bioactivity.
CARBOHYDRATE POLYMERS
(2021)
Article
Polymer Science
Zhe Wang, Na Lin, Hongliang Kang, Xinmin Hao, Ruigang Liu
Summary: The miscibility, crystallization behaviors, and morphology of polyamide 56/polyamide 6 (PA56/PA6) blends were studied. The results showed that PA56 and PA6 were miscible in the blends, evident from the presence of only one glass transition temperature (Tg). The interaction between PA56 and PA6 in the blends led to a depression in the melting point, crystallization temperature, and crystallinity of the blends. Both PA56 and PA6 maintained their crystalline structure and crystallized separately in both isothermal and non-isothermal crystallization processes. PA56 crystallized in all blending ratios, while PA6 only crystallized with a PA6 content of phi 6 > 0.2. The crystals of PA56 and PA6 grew in the same crystal skeleton but in different layers. The addition of a small amount of PA6 in PA56 significantly improved the elongation at break without sacrificing the strength, indicating a promising approach for fabricating polyamide materials with desired properties.
Article
Environmental Sciences
Aminoddin Haji, Fatemeh Shahmoradi Ghaheh, Lida Mohammadi
Summary: In this study, the natural dyeing of nylon fabric using dragon's blood resin extract was investigated and the process variables were optimized. The results showed that dragon's blood resin had good dyeing effect and colorfastness properties, making it a promising eco-friendly natural colorant source for sustainable nylon dyeing.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Materials Science, Ceramics
Mengxing Ge, Deqiao Xie, Chen Jiao, Youwen Yang, Lida Shen, Mingbo Qiu, Hanxu Zhang, Zhijing He, Huixin Liang, Zongjun Tian
Summary: The effect of magnesium oxide content on the biocompatibility and mechanical properties of magnesium oxide-calcium phosphate composite ceramic scaffolds was studied. The results showed that high magnesium oxide content enhanced the mechanical properties and achieved well biocompatibility of the composite scaffolds.
CERAMICS INTERNATIONAL
(2022)
Article
Polymer Science
Heru S. B. Rochardjo, Cahyo Budiyantoro
Summary: The study optimized the injection molding parameters for pretensioned unidirectional carbon fiber and glass fiber composite to achieve the best flexural strength, impact strength, and interlaminar properties. Through Box-Behnken design and analysis of variance, the accuracy of performance prediction for the hybrid composite material was improved.
Article
Biochemistry & Molecular Biology
Igor Rzhepakovsky, Sergey Piskov, Svetlana Avanesyan, Marina Sizonenko, Lyudmila Timchenko, Oxana Anfinogenova, Andrey Nagdalian, Andrey Blinov, Evgeniya Denisova, Stanislav Kochergin, Sergey Kubanov, Magomed Shakhbanov, Mohammad Ali Shariati, Mohammad S. Mubarak
Summary: Pure and porous bacterial cellulose scaffolds were synthesized using Medusomyces gisevii Sa-28 bacterial strain. Modification with gelatin increased the biocompatibility and solubility of the scaffolds. The scaffolds exhibited uniform distribution of pores, promoting new blood vessel growth and collagen fiber formation. The results suggest that these scaffolds can be used for engineering hard and soft tissues.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Materials Science, Ceramics
Anchao Zou, Huixin Liang, Chen Jiao, Mengxing Ge, Xinyu Yi, Youwen Yang, Jun Sun, Changjiang Wang, Lida Shen, Yao Li
Summary: This study investigated the improvement of sintering performance and degradation rate of calcium silicate ceramics by adding strontium phosphate, and found that the addition of Sr element had a positive effect on cell proliferation and differentiation.
CERAMICS INTERNATIONAL
(2021)
Article
Materials Science, Multidisciplinary
Chen Jiao, Deqiao Xie, Zhijing He, Huixin Liang, Lida Shen, Youwen Yang, Zongjun Tian, Guofeng Wu, Changjiang Wang
Summary: This study investigates the effects of structural parameters and material on the mechanical properties and biocompatibility of bone scaffolds. Through bio-inspired design and ceramic digital light processing technique, porous scaffolds with varying irregularity and porosity were fabricated. The results showed that the scaffolds had comparable mechanical properties to cancellous bone and exhibited good biocompatibility, promoting cell proliferation and differentiation. These findings suggest that bio-inspired bone scaffolds with excellent comprehensive properties can be obtained through reasonable design.
MATERIALS & DESIGN
(2022)
Article
Chemistry, Physical
Hung-Yang Lin, Yi-Jung Lu, Hsin-Hua Chou, Keng-Liang Ou, Bai-Hung Huang, Wen-Chien Lan, Takashi Saito, Yung-Chieh Cho, Yu-Hsin Ou, Tzu-Sen Yang, Pei-Wen Peng
Summary: This study successfully synthesized biphasic calcium phosphate ceramics from coral, which showed good biocompatibility and was non-cytotoxic. Different from autogenous bone, this ceramic did not induce significant differences in local tissue reaction.
Article
Engineering, Biomedical
Xiaolian Niu, Miao Qin, Mengjie Xu, Liqin Zhao, Yan Wei, Yinchun Hu, Xiaojie Lian, Song Chen, Weiyi Chen, Di Huang
Summary: The study involved the fabrication of electrospun PA6/CS scaffolds using electrospinning technology, followed by mineralization in 1.5x simulated body fluid to grow hydroxyapatite layer on the surface. The resulting scaffolds exhibited excellent biocompatibility, mechanical properties, and mimicry of natural ECM structure. The research findings highlight the potential of these mineralized PA6/CS composite scaffolds for bone tissue engineering applications.
BIOMEDICAL MATERIALS
(2021)
Article
Polymer Science
Noureddine Akartasse, Khalil Azzaoui, Elmiloud Mejdoubi, Lhaj Lahcen Elansari, Belkhir Hammouti, Mohamed Siaj, Shehdeh Jodeh, Ghadir Hanbali, Rinad Hamed, Larbi Rhazi
Summary: This study aimed to purify water from toxic metals by preparing a composite film using hydroxyapatite, chitosan, and glycerol. The composite film exhibited a homogeneous and smooth surface, and showed effective adsorption of Cd2+ and Zn2+ ions from aqueous solutions. Physico-chemical characterization and adsorption studies demonstrated the promising potential of the composite film for industrial and biological applications.
Article
Materials Science, Composites
Soner Savas, Hilal Pecenek, Lemiye Atabek Savas, Mehmet Dogan
Summary: The main purpose of this research is to investigate the use of ceramic microspheres as a filler in polyamide 6 to enhance its mechanical and wear resistance properties. The study demonstrates that the addition of ceramic microspheres significantly improves the mechanical and wear resistance properties of the composites, including tensile strength, tensile modulus, flexural strength, and flexural modulus. Specifically, the composite containing 40% ceramic microspheres exhibits 60% higher wear resistance compared to pure polyamide 6.
JOURNAL OF REINFORCED PLASTICS AND COMPOSITES
(2023)
Article
Polymer Science
Yadong Wu, Yunfeng Wang, Fang Wang, Yudong Huang, Jinmei He
Summary: This study introduces a PLA/BC composite scaffold prepared by 3D printing, which exhibits good mechanical properties, biocompatibility, and blood compatibility. The hydrophilicity of the scaffold can be adjusted by the amount of added PLA. The surface with regular circular pore and stripe structures promotes cell proliferation more effectively.
Article
Engineering, Biomedical
Hanxu Zhang, Chen Jiao, Zibo Liu, Zhijing He, Mengxing Ge, Zongjun Tian, Changjiang Wang, Zhen Wei, Lida Shen, Huixin Liang
Summary: This study used calcium silicate as the matrix and added hydroxyapatite and strontium phosphate to improve the biological activity of the scaffold. The addition of calcium sulfate dihydrate was found to enhance cell proliferation and differentiation, as well as influence the degradation properties of the ceramic scaffold. The research demonstrated the potential application value of the composite material for bone repair, with improved compressibility and retention of compressive strength after immersion in simulated body fluid.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2021)
Article
Materials Science, Biomaterials
Mengxing Ge, Deqiao Xie, Youwen Yang, Huixin Liang, Jiasen Gu, Qiuwei Zhang, Jianling Xie, Zongjun Tian
Summary: Recent advancements in medical engineering have led to the development of composite ceramic samples with improved biocompatibility and degradation rates for bone repair. The study found that increasing the MgO content in the samples enhanced their biocompatibility but reduced their antibacterial activity. The 20% calcium phosphate content group showed the best biocompatibility among the composite material samples.
BIOMATERIALS ADVANCES
(2023)
Article
Environmental Sciences
Yan Wan, Qiang Zeng, Pujiang Shi, Yong-Jin Yoon, Chor Yong Tay, Jong-Min Lee
Summary: In this study, a novel brominated flame retardant, TBBPA-bis-(2,3-dibromopropyl ether) (TBBPA-DBP), was extracted using ultrasonic-assisted solvothermal extraction. Response Surface Methodology (RSM) achieved by machine learning (support vector regression, SVR) was employed to estimate the optimal extraction conditions, which were successfully validated.
Article
Environmental Sciences
Pujiang Shi, Chiew Kei Tan, Zhuoran Wu, Jean-Christophe P. Gabriel, Madhavi Srinivasan, Jong-Min Lee, Chor Yong Tay
Summary: The reuse of electronic wastes is crucial for a sustainable circular economy, providing a simple way to extend the lifespan of non-renewable resources. This study found that discarded computer plastics can be repurposed as substrate materials to guide the growth and differentiation of stem cells without the need for further processing or biochemical modification.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Engineering, Biomedical
Hui Yang, Yinchun Hu, Min Kang, Huixiu Ding, Yue Gong, Xiangfei Yin, Ruize Sun, Yuhong Qin, Yan Wei, Di Huang
Summary: In this study, a G-GH/CL-CD-MOF@IBU composite hydrogel was prepared, which exhibited certain mechanical properties and sustained drug release behavior. It also showed good biocompatibility during co-culture with cells, indicating its potential application in OA treatment.
BIOMEDICAL MATERIALS
(2022)
Review
Materials Science, Multidisciplinary
Weiwei Lan, Xiaobo Huang, Di Huang, Xiaochun Wei, Weiyi Chen
Summary: Three-dimensional (3D) printing technology plays a crucial role in bone tissue engineering, allowing for personalized treatment by fabricating customized scaffolds based on patients' imaging data. The application of high-strength hydrogels in 3D printing for bone tissue engineering is promising.
JOURNAL OF MATERIALS SCIENCE
(2022)
Article
Biotechnology & Applied Microbiology
Yan Wan, Qiang Zeng, Insup Kim, Pujiang Shi, Yong-Jin Yoon, Chor Yong Tay, Jong-Min Lee
Summary: The extensive use of electronic and electrical equipment generates a large amount of e-waste plastics that need to be disposed of properly. This study focuses on removing a novel brominated flame retardant (BFR) known as TBBPA-DBMP using an extraction process aided by ultrasonic in alcohol extractants. Predictive models were developed to determine the optimal extraction conditions in methanol and ethanol solvents. The results showed high extraction efficiencies of TBBPA-DBMP under the optimized conditions. The validity of the predicted optimal extraction conditions was also verified.
ENVIRONMENTAL TECHNOLOGY & INNOVATION
(2022)
Article
Engineering, Biomedical
Chaima Merzougui, Fenyan Miao, Ziming Liao, Longfei Wang, Yan Wei, Di Huang
Summary: Antibacterial nanofibers, with their unique features and structural similarities, have been proposed as an interesting material for wound healing management. They can be loaded with antibacterial compounds using various methods, making them suitable for electrospun wound dressings.
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
(2022)
Article
Biophysics
Yuhui Wang, Shilong Ma, Xuanyu Liu, Yan Wei, Ziwei Liang, Yinchun Hu, Xiaojie Lian, Di Huang
Summary: Hepatocellular carcinoma (HCC) is a highly deadly tumor with a significant rate of recurrence and metastasis. Cancer stem cells (CSCs) play a crucial role in these processes, providing a new perspective on liver cancer development. A study utilized composite magnetic nanocubes modified with polyethyleneimine (PEI) and hyaluronic acid (HA) to target HCC stem cells. The nanocubes successfully recognized the stem cells through receptor-ligand binding. The study also showed that the nanocubes inhibited HCC cell proliferation and migration by regulating the expression of epithelial-mesenchymal transition (EMT) markers.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2023)
Article
Engineering, Multidisciplinary
Huilun Xu, Kejun Liu, Yimeng Su, Zhengjiang Liu, Yan Wei, Yinchun Hu, Liqin Zhao, Lingfeng Chen, Xiaojie Lian, Di Huang
Summary: Cardiovascular disease is the leading cause of death and creating reliable small diameter artificial blood vessels remains a challenge. To meet the requirements, researchers have successfully developed a micro diameter vessel using polyvinyl alcohol and alginate interpenetrating polymer networks through coaxial printing. The artificial blood vessel combines high strength and mimics the compliance of natural blood vessels. It also exhibits excellent anticoagulation properties and promotes tissue integration after implantation.
COMPOSITES PART B-ENGINEERING
(2023)
Review
Chemistry, Inorganic & Nuclear
Su Yimeng, Xu Huilun, Liao Ziming, Liu Kejun, Merzougui Chaima, Zhang Xiangyu, Hu Yinchun, Wei Yan, Huang Di
Summary: This review summarizes the synthetic methods, antibacterial mechanisms, and applications of copper-based nanoparticles, and discusses the prospects of copper-based nanoparticle antibacterial agents in biomedical and clinical fields.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
(2023)
Article
Materials Science, Biomaterials
Ziming Liao, Luyao Zhang, Weiwei Lan, Jingjing Du, Yinchun Hu, Yan Wei, Ruiqiang Hang, Weiyi Chen, Di Huang
Summary: Titanium (Ti) is a commonly used dental implant material due to its good biocompatibility and mechanical property. However, its poor biological activity limits its ability to bond with bony tissues. In this study, a two-step hydrothermal treatment method was used to prepare a Ti phosphate/nano-hydroxyapatite (TiP-Ca) composite coating on the Ti surface. The composite coating showed high bonding strength with the Ti implant and promoted cell adhesion and expression of bone-related genes. It also enhanced osseointegration in vivo, suggesting its potential for clinical application.
BIOMATERIALS SCIENCE
(2023)
Article
Engineering, Biomedical
Yu Gu, Fenyan Miao, Kejun Liu, Yimeng Su, Yan Wei, Yinchun Hu, Xiaojie Lian, Weimo Han, Weiyi Chen, Di Huang
Summary: In this study, a conductive hydrogel was prepared using gelatin methacryloyl (GelMA) and graphene oxide (GO) by adjusting their concentrations during the cross-linking process. The addition of 0.1% GO improved the mechanical properties of the hydrogel to 16.37 +/- 1.89 KPa, while the conductivity increased to 1.36 +/- 0.09 mu S/cm. Mineralization of the hydrogel significantly enhanced its mechanical properties to 26.38 +/- 2.29 KPa. Cell experiments demonstrated that electrical stimulation of the mineralized hydrogel improved the alkaline phosphatase activity of the cells. GelMA/GO conductive hydrogel shows promise for bone repair and tissue engineering.
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
(2023)
Correction
Engineering, Biomedical
Hui Yang, Yinchun Hu, Min Kang, Huixiu Ding, Yue Gong, Xiangfei Yin, Ruize Sun, Yuhong Qin, Yan Wei, Di Huang
BIOMEDICAL MATERIALS
(2023)
Article
Cell & Tissue Engineering
Tianyu Zhang, Jingxuan Li, Yahui Wang, Weimo Han, Yan Wei, Yinchun Hu, Ziwei Liang, Xiaojie Lian, Di Huang
Summary: This article discusses the use of polyurethane (PU) combined with hydroxyapatite (HA) as a composite material for bone tissue engineering. The HA/PU nanocomposite scaffold material has been proven suitable for bone tissue engineering repair. The article reviews the design, synthesis, modification, and biological attributes of HA/PU scaffolds for bone tissue engineering.
TISSUE ENGINEERING PART B-REVIEWS
(2023)
Review
Materials Science, Multidisciplinary
Jingxuan Li, Tianyu Zhang, Ziming Liao, Yan Wei, Ruiqiang Hang, Di Huang
Summary: Titanium and its alloys are widely used implant materials in orthopedics, but their inherent biological inertness limits osseointegration and antibacterial ability. Hydroxyapatite is a commonly used bioactive coating material that can improve bone integration. This article introduces the crystal structure and characteristics of HA, the principle of doping ions into HA, and the preparation methods for depositing HA coatings on titanium surfaces.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2023)
Article
Materials Science, Biomaterials
Yu Cao, Longfei Wang, Xiumei Zhang, Yi Lu, Yan Wei, Ziwei Liang, Yinchun Hu, Di Huang
Summary: In this study, hydrogel dressings with adjustable contractility and adhesion were fabricated, which can rapidly close wounds, adjust shrinkage rate, and achieve high adhesion strength and regional adhesion. Sutures-free wound closure can be achieved by adjusting the material temperature, and the dressings can promote scar-free wound healing.
REGENERATIVE BIOMATERIALS
(2023)
