Article
Engineering, Environmental
Ting Sun, Xiangning Liu, Xiaozhen Zhan, Lingling Ou, Renfa Lai
Summary: This study investigated the hepatic biodistribution and toxicological effects of zirconia nanoparticles after intravenous administration, revealing continuous accumulation in the liver with induced steatosis, functional injury, and inflammatory response. Gene alterations were involved in metabolism, cellular processes, and human diseases, especially lipid biosynthesis and metabolism pathways. In vitro studies showed oxidative stress, lipid accumulation, cell apoptosis, and P53-mediated signaling pathway activation in HepG2 cells. The findings suggest potential hepatotoxicity of ZrO2-NPs in biomedical applications and industrial exposure.
PROCESS SAFETY AND ENVIRONMENTAL PROTECTION
(2021)
Article
Biochemical Research Methods
Saara Kuusinen, Miikka Ekman, Kirsti Raiko, Heidi Hannula, Annika Lyytikainen, Satu Lahtinen, Tero Soukka
Summary: This study identified complement component C1q as the major interfering protein in nanoparticle sandwich immunoassays. Increasing the ionic strength of the assay buffer or adding a negatively charged blocker can eliminate this interference.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Materials Science, Composites
M. J. Tommalieh
Summary: A new composite material, Chitosan/Poly (Vinyl Alcohol) blend embedded by bismuth(III) oxide nanoparticles (Bi2O3 NPs), was prepared to improve electrical properties. XRD analysis revealed the crystal structure characteristics and average crystal size of the bismuth oxide nanoparticles, while vibration frequencies confirmed the presence of the nanoparticles. Conductivity and space charge volume increased due to the pathways between the bismuth nanoparticles.
COMPOSITES COMMUNICATIONS
(2021)
Article
Materials Science, Multidisciplinary
Wanda Celentano, Marco Pizzocri, Filippo Moncalvo, Federico Pessina, Michela Matteoli, Francesco Cellesi, Lorena Passoni
Summary: Doxorubicin-loaded polymer nanoparticles based on poly(ethylene glycol)-poly(epsilon-caprolactone) copolymers with complex macromolecular topology were developed for targeting the tumor microenvironment rich in matrix metalloproteinase (MMP). Different copolymers with varied structures were synthesized to control the size and DOX loading of self-assembled nanoparticles. The optimized nanocarriers were conjugated with MMP2-cleavable polyanionic inhibitory domain peptides. The results showed that these nanocarriers exhibited excellent cellular uptake and cytotoxicity in MMP2-overexpressing tumor cells.
ACS APPLIED POLYMER MATERIALS
(2022)
Article
Biophysics
Renata Guimaraes de Sa, Tatiane Moraes Arantes, Erenilda Ferreira de Macedo, Luisa Molina Dona, Jeniffer C. F. Pereira, Carolina Ramos Hurtado, R. Jose Varghese, Oluwatobi Samuel Oluwafemi, Dayane Batista Tada
Summary: This study focused on the evaluation of the photoprotective activity and cytotoxicity of zirconia nanoparticles. The results showed that ZrO2 NPs exhibited low cytotoxicity and provided effective protection under UV irradiation.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Article
Chemistry, Multidisciplinary
Maria Suciu, Claudiu Mirescu, Izabell Craciunescu, Sergiu Gabriel Macavei, Cristian Leostean, Razvan Stefan, Loredana E. Olar, Septimiu-Cassian Tripon, Alexandra Ciorita, Lucian Barbu-Tudoran
Summary: This study evaluated the in vivo distribution of synthesized SPIONs-PEG in rats and their effects on organ tissues, showing good dispersal in the bloodstream and relatively good biocompatibility, with minor to transient pathological effects observed in the liver, kidney, brain, and lungs.
Article
Chemistry, Analytical
Huiyang Xu, Chuang Guo, Weijian Yuan, Wenna Zhang, Qiu Sun, Jianfeng Wu, Xuelin Zhang
Summary: In this study, a simple and portable electrochemical sensor based on laser-induced graphene (LIG) was developed to detect organophosphorus pesticides (OPs). The LIG-based electrode showed high electrochemical activity and electron transfer. Zirconium dioxide nanoparticles were used to improve the adsorption capacity of the electrode, and the effect of different binders was investigated. β-cyclodextrin was found to increase the electrochemical activity and peak current of the electrode. The sensor demonstrated a low detection limit, high sensitivity, and good interference resistance.
Article
Chemistry, Analytical
Huiyang Xu, Chuang Guo, Weijian Yuan, Wenna Zhang, Qiu Sun, Jianfeng Wu, Xuelin Zhang
Summary: A simple and portable electrochemical sensor based on laser-induced graphene (LIG) has been developed to detect organophosphorus pesticides (OPs) with high sensitivity and interference resistance.
Article
Chemistry, Multidisciplinary
Magnus Klove, Rasmus Stubkjaer Christensen, Ida Gjerlevsen Nielsen, Sanna Sommer, Mads Ry Vogel Jorgensen, Ann-Christin Dippel, Bo Brummerstedt Iversen
Summary: The structures of Zr4+ ions in solution were studied using X-ray pair distribution function (PDF) analysis. It was found that [Zr-4(OH)8(OH2)16]8+ tetramers are predominant in water, while monomeric complexes exist in non-aqueous solvents. The PDF analysis also revealed second sphere coordination of chloride counter ions to the aqueous tetramers.
Article
Biochemistry & Molecular Biology
Jiaqi Wu, Limei Wang, Bin Qi
Summary: In this study, PLA/PBAT composites were prepared by blending PLA with PBAT and adding MDI and ChNPs as compatibilizers. The addition of both MDI and ChNPs improved the properties of the composites by potentially reducing their crystallinity, increasing the melt peak temperature, wetting the boundary of the phases, reducing the size and number of dispersed phases, and improving interfacial compatibility. MDI increased tensile strength, while ChNPs enhanced elongation at break. MDI conferred enhanced moisture resistance, while ChNPs seemed to weaken moisture resistance.
Article
Polymer Science
Alexandra L. Nikolaeva, Alexander N. Bugrov, Maria P. Sokolova, Elena M. Ivan'kova, Ivan Abalov, Elena N. Vlasova, Iosif Gofman
Summary: By studying the fabrication and characterization of polyimide/metal oxide nanocomposite films, we have identified trends in the functional properties of these materials based on factors such as the type, size, concentration of the nanofiller, and the chemical structure of the matrix polyimide.
Article
Chemistry, Applied
Cheirmadurai Kalirajan, Haripriya Behera, Vimalraj Selvaraj, Thanikaivelan Palanisamy
Summary: Hybrid biomaterials incorporated with active ingredients and metal nanoparticles are gaining interest due to their increased wound healing capacity. In this study, hybrid collagen scaffolds stabilized with oxidized inulin and ZrO2 nanoparticles were prepared for biomedical applications. The results showed that these hybrid collagen scaffolds possess good biocompatibility and healing ability, making them suitable for tissue engineering applications.
CARBOHYDRATE POLYMERS
(2022)
Article
Materials Science, Multidisciplinary
Nisha Kumari, Vivek Anand, Shweta Sareen, Prashant Choudhary, Neha Kondal, Manpreet Kaur Aulakh, Ajay Sharma, Meenakshi Verma, S. K. Mehta, Vishal Mutreja
Summary: Spherical zirconia nanoparticles were successfully synthesized using a plant-mediated method and characterized in this study. The prepared nanoparticles exhibited crystalline nature and showed both monoclinic and tetragonal phases. The mechanism of preparation and stabilization of zirconia nanoparticles using organic components of tea extracts was studied theoretically. The nanoparticles were also evaluated for their photocatalytic and antimicrobial activity.
MATERIALS CHEMISTRY AND PHYSICS
(2023)
Article
Materials Science, Ceramics
Waheed Ahmed, Javed Iqbal
Summary: Pure ZrO2 and Ni-doped ZrO2 (NZ) based effective photocatalysts were synthesized using a robust co-precipitation method, showing excellent properties in morphology and structure. NZ NPs exhibited good photocatalytic efficiency in the visible light range and have potential applications in wastewater treatment and spintronics devices.
CERAMICS INTERNATIONAL
(2021)
Article
Chemistry, Multidisciplinary
Ali Boumeftah, Abdelkader Belmokhtar, Abdelghani Benyoucef
Summary: In this study, innovative hybrid composites based on PDDS and TiO2 nanoparticles were synthesized. The structural and morphological analysis showed improved adsorption capacity and tuned optical band gap in the nanocomposites. The composites also exhibited good electroactivity response.
RESEARCH ON CHEMICAL INTERMEDIATES
(2022)
Article
Biochemistry & Molecular Biology
Valentina A. Petrova, Natallia V. Dubashynskaya, Iosif V. Gofman, Alexey S. Golovkin, Alexander I. Mishanin, Arthur D. Aquino, Daria V. Mukhametdinova, Alexandra L. Nikolaeva, Elena M. Ivan'kova, Alexander E. Baranchikov, Alexander V. Yakimansky, Vladimir K. Ivanov, Yury A. Skorik
Summary: Polymeric nanocomposite materials have the potential to enhance tissue-engineered scaffolds by influencing the structure and properties of polymeric materials and regulating cell behavior. In this study, cerium oxide nanoparticles were incorporated into a chitosan film to promote the proliferation of mesenchymal stem cells. The resulting CS-CeONP films exhibited good biocompatibility and regenerative potential in both in vitro and in vivo experiments.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Svetlana Laishevkina, Tatiana Kuleshova, Gayane Panova, Elena Ivan'kova, Olga Iakobson, Anatoly Dobrodumov, Natalia Shevchenko, Alexander Yakimansky
Summary: Polymeric hydrogels based on sulfo-containing comonomers were synthesized and their morphology and swelling behavior were explored. The cryogels formed in the presence of nanodiamonds showed high biological activity during seed germination and promoted plant growth. These results demonstrate the potential of sulfonic cryogels as environmentally friendly materials for agricultural applications.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Valentina A. A. Petrova, Iosif V. V. Gofman, Natallia V. V. Dubashynskaya, Alexey S. S. Golovkin, Alexander I. I. Mishanin, Elena M. M. Ivan'kova, Dmitry P. P. Romanov, Albert K. K. Khripunov, Elena N. N. Vlasova, Alexandra V. V. Migunova, Alexander E. E. Baranchikov, Vladimir K. K. Ivanov, Alexander V. V. Yakimansky, Yury A. A. Skorik
Summary: New composite films were prepared by incorporating bacterial cellulose nanofibers and cerium oxide nanoparticles into chitosan matrices. The amount of nanofillers affected the structure and properties of the composites, including film stiffness and strength. Increasing the concentration of nanoceria improved the biocompatibility and adhesion of the films to mesenchymal stem cells. These nanocomposite films exhibit favorable properties for use as matrix materials in cell culture and wound dressings.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Polymer Science
Gleb Vaganov, Elena Ivan'kova, Andrey Didenko, Elena Popova, Valentina Smirnova, Vladimir Elokhovskiy, Vladimir Yudin
Summary: In this study, the properties of carbon fiber reinforced plastics (CFRPs) based on semicrystalline polyimide R-BAPB were compared with highly heat-resistant thermoplastic polymers, Ultem-1000 and PEEK. The CFRPs based on PEEK and R-BAPB exhibited the highest thermal stability and heat resistance. Among all the studied CFRPs, the highest interlaminar fracture toughness was observed in CFRPs based on semicrystalline R-BAPB.
JOURNAL OF APPLIED POLYMER SCIENCE
(2023)
Article
Polymer Science
N. A. Zavrazhnykh, I. Yu. Sapurina, M. A. Shishov, E. M. Ivan'kova, V. P. Orlov, V. E. Yudin
Summary: Electroconductive scaffolds for tissue engineering with different shapes were prepared using two biocompatible polymers: polylactide and polypyrrole. The composite scaffolds were based on porous permeable films or tubes of electrospun polylactides. An electroconductive layer of polypyrrole was applied onto the surface of the scaffolds consisting of interwoven fibers of micron-scale thickness. The structure and properties of the tissue engineering scaffolds, including their mechanical, redox, and electroconductive properties, were investigated. It was found that the scaffolds remained stable during prolonged application of cyclic potentials for electrical stimulation.
POLYMER SCIENCE SERIES A
(2023)
Article
Polymer Science
E. A. Arlakova, I. V. Zubrov, A. M. Bochek, N. N. Saprykina, E. M. Ivan'kova, V. K. Lavrent'ev, V. E. Yudin
Summary: The kinetics of producing nanofibrils from chitin of various origins through acid hydrolysis was investigated. The splitting process of microparticles into nanoscale fibrils was studied using scanning electron microscopy, revealing differences in their geometric sizes.
POLYMER SCIENCE SERIES B
(2023)
Article
Polymer Science
Pavel Dorovatovskii, Marina Baidakova, Elena Ivan'kova, Vyacheslav Marikhin, Liubov Myasnikova, Roman Svetogorov, Maria Yagovkina
Summary: Nowadays, a solvent-free method for producing high performance fibers directly from ultrahigh-molecular-weight polyethylene (UHMWPE) reactor powder is being developed. The morphology and behavior of reactor particles in thermal and mechanical fields have been studied. The content of the monoclinic phase in reactor powders was found to depend on the catalyst used for synthesis and the applied pressure. Different types of monoclinic phases were identified: a structurally stabilized monoclinic phase formed during synthesis, and a monoclinic phase resulting from plastic deformation during compaction at room temperature.
Article
Polymer Science
Alexandra L. L. Nikolaeva, Alexander N. N. Bugrov, Maria P. P. Sokolova, Igor V. V. Kuntsman, Elena N. N. Vlasova, Elena M. M. Ivan'kova, Ivan V. V. Abalov, Iosif V. V. Gofman
Summary: This paper reports on novel polyimide (PI) nanocomposites filled with binary mixtures of metal oxide nanoparticles and nanocarbon materials. The structure, morphology, thermal, and mechanical properties of the materials were comprehensively studied. The synergistic effect of the nanoconstituents on various functional characteristics of the PIs was revealed, and the possibility of manipulating the material properties by choosing the proper combination of nanofillers was demonstrated. This research provides a platform for the design of PI-based engineering materials with tailored characteristics for extreme conditions.
Correction
Nanoscience & Nanotechnology
Boris V. Vasil'ev, Ruslan Yu. Smyslov, Demid A. Kirilenko, Ilya S. Kritchenkov, Alexander N. Bugrov
Summary: This paper is a corrigendum related to the article Vasil'ev B.V., Smyslov R.Yu., Kirilenko D.A., Bugrov A.N. Synthesis and magnetic properties of cobalt ferrite nanoparticles formed under hydro and solvothermal condition. Nanosystems: Phys. Chem. Math., 2021,12 (4), P. 492-504.
NANOSYSTEMS-PHYSICS CHEMISTRY MATHEMATICS
(2023)
Article
Polymer Science
O. D. Iakobson, E. M. Ivan'kova, G. V. Vaganov, E. L. Krasnopeeva, N. N. Shevchenko
Summary: Submicron composite particles with a core/shell structure were synthesized by seeded emulsion polymerization and their ability to self-assemble into 3D ordered thin-film structures was studied. The results showed that particles with a shell thickness of 10-35 nm were synthesized under the experimental conditions. The composition of the shell had an impact on the morphology and structure of the surface layer of the composite particles.
POLYMER SCIENCE SERIES B
(2023)
Article
Polymer Science
Angelina P. Prosvirnina, Alexander N. Bugrov, Natalya V. Bobrova, Eugene V. Sivtsov, Alexandra L. Nikolaeva, Almaz M. Kamalov, Maria P. Sokolova, Michael A. Smirnov
Summary: Inks for 3D printing were prepared by dispersing methacrylate-functionalized bacterial cellulose nanofibers (CNF) in a polymerizable deep eutectic solvent (DES) with water as a cosolvent. The resulting 3D-printed gels were composed of chemically and physically crosslinked networks formed from modified CNF and polymerized DES, respectively. The addition of water improved the mechanical properties of the composite gel, while an anhydrous system exhibited better shape memory properties.
Article
Polymer Science
Gleb Vaganov, Maria Simonova, Margarita Romasheva, Andrey Didenko, Elena Popova, Elena Ivan'kova, Almaz Kamalov, Vladimir Elokhovskiy, Vyacheslav Vaganov, Alexander Filippov, Vladimir Yudin
Summary: This study investigates the influence of the molecular weight of partially crystalline polyimide R-BAPB on the thermophysical and mechanical properties of carbon plastics for the first time. The molecular weight of polyimide was determined using light scattering and intrinsic viscosity of polyamic acid solutions. The increase in molecular weight leads to enhanced glass transition and thermal decomposition temperatures, but decreased degree of crystallinity of CFRP. However, an increase in molecular weight of the binder polymer significantly improves interlayer fracture toughness.
Article
Polymer Science
Artem Borisov, Yuri Boiko, Svetlana Gureva, Ksenia Danilova, Victor Egorov, Elena Ivan'kova, Vyacheslav Marikhin, Liubov Myasnikova, Ludmila Novokshonova, Elena Radovanova, Elena Starchak, Tatiana Ushakova, Maria Yagovkina
Summary: This study investigated the morphology of virgin reactor powder (RP) of high-density polyethylene (HDPE) with a molecular weight of 160,000 g/mol using various methods. The results showed that the RP consisted of macro- and micro-shish-kebab structures with different dimensions, as well as individual lamellae of folded chain crystals. Analysis also revealed the presence of multiple periodic morphoses in the RP and their correlation with the observed powder morphology. The study estimated the thickness and surface energy of the lamellae in each period and discussed the presence of folds on their surfaces. It was suggested that the specific structure of HDPE RP was attributed to the peculiarities of polymer crystallization during suspension synthesis in a quasi-stationary regime.
Article
Polymer Science
Nurjemal A. Tagandurdyyeva, Maxim A. Trube, Igor' O. Shemyakin, Denis N. Solomitskiy, German V. Medvedev, Elena N. Dresvyanina, Yulia A. Nashchekina, Elena M. Ivan'kova, Irina P. Dobrovol'skaya, Almaz M. Kamalov, Elena G. Sukhorukova, Olga A. Moskalyuk, Vladimir E. Yudin
Summary: New tubular conduits consisting of poly (L-lactide) nanofibers and chitosan composite fibers with chitin nanofibrils have been developed for peripheral nerve regeneration and repair. In vitro studies showed good biocompatibility with human embryonic bone marrow stromal cells (FetMSCs), with cell adhesion and differentiation observed just one day after cultivation. An in vivo study evaluating motor-coordination disorders using the sciatic nerve functional index (SFI) assessment demonstrated an increased regeneration rate of the sciatic nerve with the presence of chitosan monofibers and chitosan composite fibers with chitin nanofibrils in the conduit design, resulting in an improved SFI value ranging from 76 to 83.
