Zinc Transporters and Zinc Signaling: New Insights into Their Role in Type 2 Diabetes

Analyzing free zinc(ii) ion concentrations in cell biology with fluorescent chelating molecules

(2015) Wolfgang Maret   Metallomics

Zinc transporter gene expression and glycemic control in post-menopausal women with Type 2 diabetes mellitus

(2014) Meika Foster et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Loss-of-function mutations in SLC30A8 protect against type 2 diabetes

(2014) Jason Flannick et al.   NATURE GENETICS

Interactions Between Zinc Transporter-8 Gene (SLC30A8) and Plasma Zinc Concentrations for Impaired Glucose Regulation and Type 2 Diabetes

(2013) Zhilei Shan et al.   DIABETES

Barriers and facilitators to diabetes self-management: Perspectives of older community dwellers and health professionals in China

(2013) Huixia Shen et al.   International Journal of Nursing Practice

Factors influencing self-management in patients with type 2 diabetes: a quantitative systematic review protocol

(2013) Annamaria Bagnasco et al.   JOURNAL OF ADVANCED NURSING

Selectivity and specificity of small molecule fluorescent dyes/probes used for the detection of Zn2+and Ca2+in cells

(2013) Julio A. Landero Figueroa et al.   Metallomics

The SLC39 family of zinc transporters

(2013) Jeeyon Jeong et al.   MOLECULAR ASPECTS OF MEDICINE

The SLC30 family of zinc transporters – A review of current understanding of their biological and pathophysiological roles

(2013) Liping Huang et al.   MOLECULAR ASPECTS OF MEDICINE

Essential Role of the Zinc Transporter ZIP9/SLC39A9 in Regulating the Activations of Akt and Erk in B-Cell Receptor Signaling Pathway in DT40 Cells

(2013) Masanari Taniguchi et al.   PLoS One

The Zinc Transporter, Slc39a7 (Zip7) Is Implicated in Glycaemic Control in Skeletal Muscle Cells

(2013) Stephen A. Myers et al.   PLoS One

Zinc homeostasis in the metabolic syndrome and diabetes

(2013) Xiao Miao et al.   Frontiers of Medicine

Effects of high-fat diet feeding on Znt8-null mice: differences between β-cell and global knockout of Znt8

(2012) A. B. Hardy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

ZnT8 and type 1 diabetes [Review]

(2012) Eiji Kawasaki   ENDOCRINE JOURNAL

Picomolar Concentrations of Free Zinc(II) Ions Regulate Receptor Protein-tyrosine Phosphatase β Activity

(2012) Matthew Wilson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Znt7-null Mice Are More Susceptible to Diet-induced Glucose Intolerance and Insulin Resistance

(2012) Liping Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Disturbed zinc homeostasis in diabetic patients by in vitro and in vivo analysis of insulinomimetic activity of zinc

(2012) Judith Jansen et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

An "Inordinate Fondness for Transporters" Explained?

(2012) D. J. Eide   Science Signaling

Protein Kinase CK2 Triggers Cytosolic Zinc Signaling Pathways by Phosphorylation of Zinc Channel ZIP7

(2012) K. M. Taylor et al.   Science Signaling

Effects of zinc supplementation on diabetes mellitus: a systematic review and meta-analysis

(2012) R Jayawardena et al.   Diabetology & Metabolic Syndrome

Zinc and human health: an update

(2011) Christos T. Chasapis et al.   ARCHIVES OF TOXICOLOGY

Metals on the move: zinc ions in cellular regulation and in the coordination dynamics of zinc proteins

(2011) Wolfgang Maret   BIOMETALS

An Overview of a Wide Range of Functions of ZnT and Zip Zinc Transporters in the Secretory Pathway

(2011) Taiho KAMBE   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Zinc transporter 8 autoantibodies in fulminant, acute-onset, and slow-onset patients with type 1 diabetes

(2011) Eiji Kawasaki et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Genetic etiology of type 2 diabetes mellitus: a review

(2011) Uma Jyothi Kommoju et al.   International Journal of Diabetes in Developing Countries

Glucose Regulates Free Cytosolic Zn2+Concentration, Slc39 (ZiP), and Metallothionein Gene Expression in Primary Pancreatic Islet β-Cells

(2011) Elisa A. Bellomo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Zinc homeostasis and signaling in health and diseases

(2011) Toshiyuki Fukada et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Investigation of the insulin-like properties of zinc(II) complexes of 3-hydroxy-4-pyridinones: Identification of a compound with glucose lowering effect in STZ-induced type I diabetic animals

(2011) Tânia Moniz et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Zinc deficiency exacerbates diabetic down-regulation of Akt expression and function in the testis: essential roles of PTEN, PTP1B and TRB3

(2011) Yuguang Zhao et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The Zinc Transporter SLC39A14/ZIP14 Controls G-Protein Coupled Receptor-Mediated Signaling Required for Systemic Growth

(2011) Shintaro Hojyo et al.   PLoS One

Imaging mobile zinc in biology

(2010) Elisa Tomat et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Zinc, zinc transporters and diabetes

(2010) J. Rungby   DIABETOLOGIA

Beta cell-specific Znt8 deletion in mice causes marked defects in insulin processing, crystallisation and secretion

(2010) N. Wijesekara et al.   DIABETOLOGIA

Over-expression of ZnT7 increases insulin synthesis and secretion in pancreatic β-cells by promoting insulin gene transcription

(2010) Liping Huang et al.   EXPERIMENTAL CELL RESEARCH

Different roles of zinc plus arachidonic acid on insulin sensitivity between high fructose- and high fat-fed rats

(2010) Inkyung Hwang et al.   LIFE SCIENCES

Mammalian Zinc Transporters: Nutritional and Physiologic Regulation

(2009) Louis A. Lichten et al.   Annual Review of Nutrition

Deletion of the mouseSlc30a8gene encoding zinc transporter-8 results in impaired insulin secretion

(2009) Lynley D. Pound et al.   BIOCHEMICAL JOURNAL

Zn2+-transporter-8: A dual role in diabetes

(2009) Dimitry A. Chistiakov et al.   BIOFACTORS

Insulin Storage and Glucose Homeostasis in Mice Null for the Granule Zinc Transporter ZnT8 and Studies of the Type 2 Diabetes-Associated Variants

(2009) T. J. Nicolson et al.   DIABETES

Zinc, a regulator of islet function and glucose homeostasis

(2009) N. Wijesekara et al.   DIABETES OBESITY & METABOLISM

Genetically Encoded Sensors to Elucidate Spatial Distribution of Cellular Zinc

(2009) Philip J. Dittmer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Zinc and diabetes — clinical links and molecular mechanisms

(2009) Judith Jansen et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Zinc-dependent effects of small molecules on the insulin-sensitive transcription factor FOXO1a and gluconeogenic genes

(2009) Amy R. Cameron et al.   Metallomics

Down-Regulation of ZnT8 Expression in INS-1 Rat Pancreatic Beta Cells Reduces Insulin Content and Glucose-Inducible Insulin Secretion

(2009) Yi Fu et al.   PLoS One

SLC30A3 Responds to Glucose- and Zinc Variations in ß-Cells and Is Critical for Insulin Production and In Vivo Glucose-Metabolism During ß-Cell Stress

(2009) Kamille Smidt et al.   PLoS One

Zinc transporters and cancer: a potential role for ZIP7 as a hub for tyrosine kinase activation

(2009) C. Hogstrand et al.   TRENDS IN MOLECULAR MEDICINE

A distinct role in breast cancer for two LIV-1 family zinc transporters

(2008) Kathryn M. Taylor   BIOCHEMICAL SOCIETY TRANSACTIONS

ZIP7-Mediated Intracellular Zinc Transport Contributes to Aberrant Growth Factor Signaling in Antihormone-Resistant Breast Cancer Cells

(2008) Kathryn M. Taylor et al.   ENDOCRINOLOGY

Diabetes-linked zinc transporter ZnT8 is a homodimeric protein expressed by distinct rodent endocrine cell types in the pancreas and other glands

(2008) C. Murgia et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Zinc signalling and subcellular distribution: emerging targets in type 2 diabetes

(2008) Eugenio Mocchegiani et al.   TRENDS IN MOLECULAR MEDICINE