Article
Health Care Sciences & Services
Paige Crompvoets, Jane M. Cramm, Elisabeth F. C. van Rossum, Anna P. Nieboer
Summary: This study aimed to explore the viewpoints of patients with obesity on the importance of different aspects of person-centred care. Five distinct viewpoints were identified, highlighting the need for tailored care in obesity treatment.
HEALTH EXPECTATIONS
(2022)
Article
Social Sciences, Interdisciplinary
Willem van der Deijl, Werner Brouwer, Job van Exel
Summary: This study examined conceptions of a good life among adult people in the Netherlands and identified five distinct viewpoints on well-being. The findings have significant implications for the development of well-being measures and policies.
APPLIED RESEARCH IN QUALITY OF LIFE
(2023)
Article
Rehabilitation
Julie Duncan Millar, Helen Mason, Lisa Kidd
Summary: This study aimed to explore the most important factors in making supported self-management (SSM) work in community stroke rehabilitation. The results identified four viewpoints, including a person-centered approach to build self-confidence and self-worth, feeling heard, understood, and supported by everybody, preparation of appropriate resources, and ensuring the right thing, right place, right time for the individual. Trusting supportive relationships, working in partnership, focusing on meaningful goals, and building self-confidence were important across all viewpoints.
DISABILITY AND REHABILITATION
(2023)
Article
Biochemistry & Molecular Biology
Tessa Gerrits, Isabella J. Brouwer, Kyra L. Dijkstra, Ron Wolterbeek, Jan A. Bruijn, Marion Scharpfenecker, Hans J. Baelde
Summary: Chronic kidney disease (CKD) involves progressive deterioration of renal function, characterized by glomerular sclerosis, tubular atrophy, and interstitial fibrosis. Endoglin, expressed in endothelial cells and fibroblasts, may function as a co-receptor of TGF signaling and potentially play a role in the progression of CKD. The study found that endoglin was upregulated in patients with CKD, particularly those with chronic allograft dysfunction and diabetic nephropathy. The overexpression of endoglin in human kidney fibroblasts also resulted in increased mRNA and protein upregulation of ECM components, suggesting its significance as a therapeutic target for the prevention of end-stage renal disease.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Computer Science, Artificial Intelligence
Andreia Martinho, Maarten Kroesen, Caspar Chorus
Summary: The study surveyed medical doctors from The Netherlands, Portugal, and the U.S. and identified four main perspectives on the ethics surrounding Health AI, including AI as a helpful tool, the importance of rules and regulations, trust in private tech companies based on ethics, and the importance of explainable AI tools. Each perspective provides valuable insights on ethical issues in the design and development of AI Health.
ARTIFICIAL INTELLIGENCE IN MEDICINE
(2021)
Article
Education, Scientific Disciplines
Jennifer Coventry, Jennifer May Hampton, Esther Muddiman, Alison Bullock
Summary: This study explores the perceptions of what makes a 'good' doctor among medical students and doctors. The findings suggest that a patient-centered approach and generalist skills are valued by the majority, aligning with the curricula adaptions made by Royal Colleges. However, the implications of a generalist approach on doctors' professional identities should be acknowledged.
Article
Biochemistry & Molecular Biology
Ziad M. El-Zaatari, Luan D. Truong
Summary: Renal cell carcinoma (RCC) occurring in the setting of end-stage renal disease (ESRD) shows unique clinicopathological characteristics, with acquired cystic kidney disease-associated renal cell carcinoma (ACKD-RCC) and clear-cell papillary renal cell carcinoma (ccpRCC) being the most frequent types. Other types of RCC also occur in ESRD, albeit with different frequencies from the non-ESRD general population. While the histological features of RCC do not vary in the setting of ESRD vs. non-ESRD, other findings, such as multifocality and multiple tumor types, are more frequent in ESRD. Studies have generated novel and important knowledge of the etiology, epidemiology, diagnosis, treatment, immunophenotype, and molecular characteristics of ESRD-associated RCC.
Article
Education & Educational Research
Youmen Chaaban, Hadeel Alkhateeb, Abdullah Abu-Tineh, Michael Romanowski
Summary: Recruiting, preparing and supporting teachers is a concern in many countries, including Qatar. This study used a Systems Theory Framework to explore the influence on Qatari teachers' career development. Q methodology was applied to reveal four distinct perspectives on career plans. Implications for policy planning are discussed.
TEACHING AND TEACHER EDUCATION
(2023)
Article
Public, Environmental & Occupational Health
Radha Maniam, Maw Pin Tan, Mei Chan Chong
Summary: This study aims to understand the subjective opinions of haemodialysis patients regarding their preferences, feelings, needs, values, and life goals in end-of-life care. The Q methodology was used to rank 37 opinion statements, and the results identified five factors, including living in the present, family preference, self-preservation, power vs. control, and autonomy in decision making. The study highlights the importance of exploring patients' preferences and initiating end-of-life care discussions based on these preferences.
PATIENT EDUCATION AND COUNSELING
(2022)
Article
Education & Educational Research
John K. Roberts, Micah Schub, Surbhi Singhal, Jamison Norwood, Thomas Cassini, Andi Hudler, Deepa Ramadurai, Christopher C. Smith, Sima S. Desai, Jennifer Weintraub, Scott H. Hasler, Tyler M. Schwiesow, Geoffrey R. Connors, Aashish Didwania, Charles W. Hargett, Myles Wolf
Summary: Career selection in medicine is a complex process that is not well-researched. A study on US internal medicine (IM) residents revealed four dominant viewpoints related to career choice: Fellowship-Bound-Academic, Altruistic-Longitudinal-Generalist, Inpatient-Burnout-Aware, and Lifestyle-Focused-Consultant. These viewpoints reflect the intersection of competing priorities, personal interests, professional identity, socio-economic factors, and work/life satisfaction. Understanding these determinants can help address physician workforce shortages and enhance professional satisfaction.
ADVANCES IN HEALTH SCIENCES EDUCATION
(2023)
Article
Multidisciplinary Sciences
Carolyn Blair, Joanne Shields, Robert Mullan, William Johnston, Andrew Davenport, Denis Fouque, Kamyar Kalantar-Zadeh, Peter Maxwell, Clare McKeaveney, Helen Noble, Sam Porter, David Seres, Adrian Slee, Ian Swaine, Miles Witham, Joanne Reid
Summary: This study aims to explore the lived experience of individuals with renal cachexia and their carers, in order to inform guidelines and future renal service planning.
Article
Nursing
Helena Sousa, Oscar Ribeiro, Alan J. Christensen, Daniela Figueiredo
Summary: This study aimed to explore the stressors and coping strategies of adult children caring for parents with ESRD undergoing haemodialysis. Findings revealed that caregiving for parents undergoing haemodialysis is a challenging experience marked by various stressors and the need to manage multiple responsibilities.
JOURNAL OF CLINICAL NURSING
(2022)
Article
Clinical Neurology
Chang Min Heo, Won Ho Lee, Bong Soo Park, Yoo Jin Lee, Sihyung Park, Yang Wook Kim, Dong Ah Lee, Byeong Cheol Yoo, Kang Min Park
Summary: This study compares glymphatic dysfunction between patients with end-stage renal disease (ESRD) and healthy controls, and reveals the presence of glymphatic dysfunction in patients with ESRD as demonstrated by the DTI-ALPS index. Additionally, a significant positive correlation is found between the DTI-ALPS index and serum parathyroid hormone levels in ESRD patients.
FRONTIERS IN NEUROLOGY
(2022)
Article
Public, Environmental & Occupational Health
Deepika Shrestha, Sally Picciotto, Michael P. LaValley, Sa Liu, S. Katharine Hammond, Daniel E. Weiner, Ellen A. Eisen, Katie M. Applebaum
Summary: Despite increasing prevalence of end-stage renal disease, this study found no overall association between metalworking fluids (MWF) and ESRD. However, there were modest associations between MWF and ESRD classification of glomerulonephritis and diabetic nephropathy. Differences by race suggest that black males may have higher disease rates following MWF exposure, indicating a need for further examination of this relationship.
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2022)
Article
Nursing
Ick-Jee Kim
Summary: This study explores societal perspectives on priorities at the end of life in South Korea and proposes strategies for establishing a well-dying culture. Four distinct perspectives on priorities at the end of life were identified: emphasizing the right to self-determination, avoiding burdening the family, putting life first, and connotations with a complex perspective.
JAPAN JOURNAL OF NURSING SCIENCE
(2022)
Article
Health Care Sciences & Services
Charlotte M. Dieteren, Vivian T. Reckers-Droog, Sara Schrama, Dynothra de Boer, Job van Exel
Summary: This study identified four distinct viewpoints on healthcare priority setting in the Netherlands, each supported by a mix of experts and members of the public. There seems to be limited support for a lifestyle criterion, particularly among the public, while experts tend to prefer the currently applied criteria. The diversity in views should be considered by policymakers aiming to align with societal preferences and increase policy acceptance.
HEALTH EXPECTATIONS
(2022)
Editorial Material
Economics
Werner Brouwer, Samare Huls, Ayesha Sajjad, Tim Kanters, Leona Hakkaart-van Roijen, Job van Exel
Article
Public, Environmental & Occupational Health
Niek Mouter, Annamarie de Ruijter, G. Ardine de Wit, Mattijs S. Lambooij, Maarten van Wijhe, Job van Exel, Roselinde Kessels
Summary: The willingness to take a COVID-19 vaccine is high among adults in the Netherlands, but a considerable proportion prefers to delay their decision to vaccinate until experiences of others are known. Age, education level, and vaccine attributes influence the willingness to vaccinate.
SOCIAL SCIENCE & MEDICINE
(2022)
Article
Public, Environmental & Occupational Health
Adrienne H. Rotteveel, Mattijs S. Lambooij, Job van Exel, G. Ardine de Wit
Summary: This study examined the viewpoints on active disinvestment among citizens in the Netherlands and found that viewpoint support is associated with citizens' background characteristics. Financial situation, educational level, healthcare utilization, and opinions on government responsibility and healthcare costs were all related to viewpoint support.
SOCIAL SCIENCE & MEDICINE
(2022)
Article
Economics
Niek Mouter, Sander Boxebeld, Roselinde Kessels, Maarten van Wijhe, Ardine de Wit, Mattijs Lambooij, Job van Exel
Summary: The study shows that Dutch citizens generally prefer policies that reward vaccination rather than punish those who reject the vaccine. Vaccinated individuals are more willing to accept policies, while those who reject vaccination have a more negative view towards them. However, vaccination passports receive widespread support.
Article
Public, Environmental & Occupational Health
Sebastian Himmler, Marcel Jonker, Frederique van Krugten, Mariska Hackert, Job van Exel, Werner Brouwer
Summary: This study established a utility tariff for the Well-being of Older People measure (WOOP), to better evaluate the full relevant benefits of health and social care interventions targeted at older people.
SOCIAL SCIENCE & MEDICINE
(2022)
Article
Economics
Meg Perry-Duxbury, Sebastian Himmler, Job van Exel, Werner Brouwer
Summary: This paper examines the willingness to pay for health gains due to an international early warning system for outbreaks in six European countries. The study finds that the willingness to pay is higher for greater risk reduction, but the changes in willingness to pay are not proportional to the magnitude of the risk reduction. The study provides estimates of the monetary value of health gains in seven different scenarios of a pandemic outbreak.
EUROPEAN JOURNAL OF HEALTH ECONOMICS
(2023)
Article
Health Care Sciences & Services
Hans-Helmut Koenig, Sebastian Neumann-Boehme, Iryna Sabat, Jonas Schreyoegg, Aleksandra Torbica, Job van Exel, Pedro Pita Barros, Tom Stargardt, Andre Hajek
Summary: This study investigated the health-related quality of life (HRQoL) during the COVID-19 pandemic in seven European countries and its association with sociodemographic and COVID-19-related variables. The findings showed that a large proportion of respondents reported problems in HRQoL dimensions throughout the pandemic, especially for anxiety/depression. Various sociodemographic and COVID-19-related variables were associated with HRQoL. Rating: 8/10
QUALITY OF LIFE RESEARCH
(2023)
Article
Economics
C. M. Dieteren, I. Bonfrer, W. B. F. Brouwer, J. van Exel
Summary: This study used a discrete choice experiment to investigate public preferences for policies promoting a healthy diet in the Netherlands. The results showed that positive financial incentives and lower tax rates received more support, but there were significant variations in preferences among the public. This highlights the challenges in selecting and implementing a policy package that has wide public support.
EUROPEAN JOURNAL OF HEALTH ECONOMICS
(2023)
Article
Economics
Werner Brouwer, Kaya Verbooy, Renske Hoefman, Job van Exel
Summary: This study found that compensation mechanisms and multiplier effects play important roles in reducing or increasing productivity losses. Survey data showed that among a sample of individuals in Amsterdam aged 15-65 years who worked at least 12 hours per week and experienced absenteeism and/or presenteeism in the past 4 weeks, 45.5% reported absenteeism (average 6.5 days), resulting in an average loss of 48.7 working hours, while 75.9% reported presenteeism, with an average loss of 10.7 working hours. Compensation mechanisms were reported by 76.9% of respondents, compensating nearly 80% of their lost production, while multiplier effects were reported by 23.6% of respondents, reducing the productivity of 4.2 colleagues by an average of 27.8%, implying a multiplier of 2.1 in that subgroup.
Article
Public, Environmental & Occupational Health
Merel A. J. van Hulsen, Kirsten I. M. Rohde, Job van Exel
Summary: Policy makers need to consider preferences from both societal and individual perspectives when making decisions about healthcare resource allocation. Preferences for investment in healthcare capacity and allocation between regions were studied through an online survey, revealing that preferences were influenced by initial waiting times and varied between individuals. It was found that both egalitarian and individualistic preferences were present, but the focus should be on the effect on final waiting time rather than the reduction of waiting time.
SOCIAL SCIENCE & MEDICINE
(2023)
Article
Economics
J. Veldwijk, J. van Exel, E. W. de Bekker-Grob, N. Mouter
Summary: This study investigated public preferences for COVID-19 certificates in the Netherlands and examined whether these preferences varied among different subgroups. The results showed that respondents aged > 65 years and those planning to get vaccinated were more likely to support the certificate. The ability to shop without appointment and visit bars and restaurants were the most important factors for respondents.
APPLIED HEALTH ECONOMICS AND HEALTH POLICY
(2023)
Article
Economics
Aemiro Melkamu Daniel, Job van Exel, Caspar G. Chorus
Summary: This study empirically investigates the influence of self-interest, positional concerns, and distributional considerations on individual healthcare decision making. The results show that distributional considerations are the most important factor, followed by self-interest and positional concerns. Furthermore, decision makers in the United States and the United Kingdom display different tendencies when making choices for themselves or for their close relatives or friends. The method used in this study helps healthcare decision makers understand the relative importance of these three motivations.
EUROPEAN JOURNAL OF HEALTH ECONOMICS
(2023)
Article
Public, Environmental & Occupational Health
Jannis Stockel, Job van Exel, Werner B. F. Brouwer
Summary: Experiencing deteriorating health can impact quality of life. The theory of adaptation suggests that individuals can adapt to living with poor health, leading to stable or improving quality of life despite continuing health decline. This has implications for measuring the impact of health changes or new medical technologies using subjective quality of life indicators. However, the existence and magnitude of adaptation vary among different diseases and subgroups, raising ethical concerns. This study used data from the UK Understanding Society survey to examine the effects of long-standing illness or disability on self-assessed health and life satisfaction. The findings indicate that disability onset is associated with significant decreases in subjective health and well-being, but these initial declines attenuate over time. The magnitude and patterns of adaptation differ across demographic and severity groups. These results have important implications for future studies on quality of life outcomes and highlight the need for careful consideration of adaptation in observational datasets.
SOCIAL SCIENCE & MEDICINE
(2023)
Article
Social Sciences, Interdisciplinary
Willem van der Deijl, Werner Brouwer, Job van Exel
Summary: This study examined conceptions of a good life among adult people in the Netherlands and identified five distinct viewpoints on well-being. The findings have significant implications for the development of well-being measures and policies.
APPLIED RESEARCH IN QUALITY OF LIFE
(2023)