Article
Plant Sciences
Samia Berraies, Richard Cuthbert, Ron Knox, Arti Singh, Ron DePauw, Yuefeng Ruan, Firdissa Bokore, Maria Antonia Henriquez, Santosh Kumar, Andrew Burt, Curtis Pozniak, Amidou N'Diaye, Brad Meyer
Summary: This study aimed to map quantitative trait loci (QTL) responsible for the expression of FHB resistance in two adapted cultivars and evaluate their co-localization with agronomic traits. It was found that FHB resistance QTL co-localized with QTL for plant height, days to heading, and days to maturity. Selecting for improved FHB resistance within adapted cultivars can be done by using markers associated with complementary QTL.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Genetics & Heredity
Junqiao Song, Yuhui Pang, Chunping Wang, Xuecai Zhang, Zhankui Zeng, Dehui Zhao, Leiyi Zhang, Yong Zhang
Summary: In this study, the QTL associated with resistance to wheat head blight caused by Fusarium verticillioides (F.v) were mapped using genotype data from a population of 262 recombinant inbred lines (RILs) derived from Zhongmai 578 and Jimai 22. A total of 22 QTL were identified, with one novel QTL and one stable QTL detected. Forty-seven candidate genes related to disease resistance were found in the interval of the QTL. Genomic prediction accuracies for the disease traits were estimated using the cross-validation scheme.
FRONTIERS IN GENETICS
(2022)
Article
Biochemistry & Molecular Biology
Carolina Sgarbi, Ismael Malbran, Luciana Saldua, Gladys Albina Lori, Ulrike Lohwasser, Mian Abdur Rehman Arif, Andreas Boerner, Marcos Yanniccari, Ana Maria Castro
Summary: The study revealed that resistance to Fusarium head blight in wheat is controlled by a complex network of 27 additive QTLs and multiple chromosomes, indicating a multifaceted genetic regulation for FHB resistance.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Agronomy
Vinay Kumar Reddy Nannuru, Susanne S. Windju, Tatiana Belova, Jon Arne Dieseth, Muath Alsheikh, Yanhong Dong, Curt A. McCartney, Maria Antonia Henriques, Hermann Buerstmayr, Sebastian Michel, Theodorus H. E. Meuwissen, Morten Lillemo
Summary: This study identified several QTL associated with FHB disease resistance in a panel of spring wheat. The research found a highly significant QTL on chromosome 7A that played a consistent role in FHB resistance. The findings provide valuable information for breeders to improve FHB resistance in wheat cultivars.
THEORETICAL AND APPLIED GENETICS
(2022)
Article
Plant Sciences
Bikash Poudel, Joseph Mullins, Krishna D. Puri, Yueqiang Leng, Anil Karmacharya, Yuan Liu, Justin Hegstad, Xuehui Li, Shaobin Zhong
Summary: The study identified four QTL for Fusarium head blight (FHB) resistance in a Brazilian spring wheat cultivar, Surpresa, with the largest effect QTL on chromosome 7A. A QTL for mycotoxin accumulation was also detected. These findings may diversify the FHB resistance gene pool and increase overall resistance to the disease in wheat.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Genetics & Heredity
Lei Wu, Xinyao He, Yi He, Peng Jiang, Kaijie Xu, Xu Zhang, Pawan K. Singh
Summary: This study screened bread wheat accessions for Fusarium head blight (FHB) resistance and identified loci associated with resistance. Several accessions with good FHB resistance were found and can be used in breeding programs in Mexico and China to improve resistance against FHB and mycotoxin accumulation in grains.
FRONTIERS IN GENETICS
(2022)
Review
Cell Biology
Chunhong Hu, Peng Chen, Xinhui Zhou, Yangchen Li, Keshi Ma, Shumei Li, Huaipan Liu, Lili Li
Summary: This review summarizes the recent advances in understanding the pathogenesis ofFusarium head blight (FHB) in wheat, including the identification of pathogenic strains, the discovery of disease-resistant genes, and the signaling pathways involved. The review also highlights the importance of maintaining intracellular ROS homeostasis in plant responses to FHB. Additionally, the article identifies breeding bottlenecks in resilient germplasm resources.
Article
Multidisciplinary Sciences
Rachel Goddard, Andrew Steed, Pedro Luiz Scheeren, Joao Leodato Nunes Maciel, Eduardo Caierao, Gisele Abigail Montan Torres, Luciano Consoli, Flavio Martins Santana, Jose Mauricio Cunha Fernandes, James Simmonds, Cristobal Uauy, James Cockram, Paul Nicholson
Summary: The study found that Brazilian wheat exhibits varying degrees of resistance to Fusarium head blight, controlled by multiple genetic loci, with two major QTL identified on chromosomes 4B and 6B showing significant associations with disease-related traits. These findings provide new genetic resources for improving wheat quality and reducing the reliance on fungicides.
Article
Plant Sciences
Jemanesh K. Haile, Demissew Sertse, Amidou N'Diaye, Valentyna Klymiuk, Krystalee Wiebe, Yuefeng Ruan, Harmeet S. Chawla, Maria-Antonia Henriquez, Lipu Wang, Hadley R. Kutcher, Barbara Steiner, Hermann Buerstmayr, Curtis J. Pozniak
Summary: Durum wheat is more susceptible to Fusarium head blight (FHB), which reduces yield and quality and contaminates the grain. A comprehensive assessment of the genetic basis of FHB resistance and DON accumulation in durum wheat was conducted, resulting in the identification of multiple quantitative trait loci (QTL) associated with FHB resistance and related traits.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Plant Sciences
Weiya Xue, Kathleen G. Haynes, Christopher R. Clarke, Xinshun Qu
Summary: This study investigates the genetic basis of early blight resistance in potato by using hybridization and field trials. Several quantitative trait loci (QTL) associated with early blight resistance were identified, providing new insights for marker-assisted selection in breeding for early blight resistance.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Agronomy
Tong Zheng, Chen Hua, Lei Li, Zhengxi Sun, Minmin Yuan, Guihua Bai, Gavin Humphreys, Tao Li
Summary: This study presents a new strategy for identifying robust and reliable meta-QTL for improving wheat resistance to FHB. Through meta-analysis, 625 original QTL from 113 publications were consolidated into 118 genetic map-based mQTL, from which 77 high-confidence mQTL were selected. By analyzing transcriptomic and proteomic data, 17 genes related to FHB and locus-specific SNP and SSR markers were identified within the selected mQTL intervals.
Article
Biochemistry & Molecular Biology
Yasir Sidiq, Masataka Nakano, Yumi Mori, Takashi Yaeno, Makoto Kimura, Takumi Nishiuchi
Summary: Nicotinamide pretreatment effectively suppresses Fusarium Head Blight in wheat plants and significantly reduces DON mycotoxin accumulation.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Agronomy
Genyuan Zhang, Runyu Hu, Xiangguo Chen, Fangfang Zhang, Yujia Li, Hao Xu, Shinan Yu, Shan Wang, Yan Gao, Qiaoyun Li, Jianwei Tang, Guihong Yin
Summary: Through testing 104 wheat cultivars, it was found that a small number of cultivars possess multiple quantitative trait loci resistant to FHB, with Fhb1 and Qfhb.crc-2D showing the best resistance effects.
Article
Plant Sciences
Yike Liu, Guang Zhu, Zhangwang Zhu, Lin Chen, Hongli Niu, Weijie He, Hanwen Tong, Jinghan Song, Yuqing Zhang, Dongfang Ma, Chunbao Gao
Summary: In this study, 240 Chinese elite wheat cultivars and lines were evaluated for Fusarium seedling blight (FSB) resistance, with 23 accessions showing potential for FSB resistance breeding. Six stable quantitative trait loci (QTLs) were detected, with four KASP markers identified for marker-assisted selection. Analysis of defense-related genes revealed candidates for mapping QTLs, providing valuable resources for wheat breeding to enhance FSB resistance.
FRONTIERS IN PLANT SCIENCE
(2021)
Article
Plant Sciences
Wenjing Hu, Derong Gao, Yong Zhang, Xu Zheng, Chengbin Lu, Hongya Wu, Weigang Xu, Shunhe Cheng, Jizeng Jia
Summary: The genetic basis of resistance to Fusarium head blight (FHB) in wheat was studied in two elite cultivars using quantitative trait loci (QTL) mapping. It was found that there is a common QTL with a large effect on FHB resistance in both cultivars, and a novel QTL was identified in one of the populations. These resistance alleles do not affect plant height or flowering dates, and have been verified to be effective in other cultivars.
Article
Multidisciplinary Sciences
Firdissa E. Bokore, Ron E. Knox, Richard D. Cuthbert, Curtis J. Pozniak, Brent D. McCallum, Amidou N'Diaye, Ron M. DePauw, Heather L. Campbell, Catherine Munro, Arti Singh, Colin W. Hiebert, Curt A. McCartney, Andrew G. Sharpe, Asheesh K. Singh, Dean Spaner, D. B. Fowler, Yuefeng Ruan, Samia Berraies, Brad Meyer
Article
Agronomy
Dinushika Thambugala, Anita L. Brule-Babel, Barbara A. Blackwell, George Fedak, Adam J. Foster, Dan MacEachern, Jeannie Gilbert, Maria Antonia Henriquez, Richard A. Martin, Brent D. McCallum, Dean Spaner, Muhammad Iqbal, Curtis J. Pozniak, Amidou N'Diaye, Curt A. McCartney
THEORETICAL AND APPLIED GENETICS
(2020)
Article
Genetics & Heredity
Mariaelisa Graff, Anne E. Justice, Kristin L. Young, Eirini Marouli, Xinruo Zhang, Rebecca S. Fine, Elise Lim, Victoria Buchanan, Kristin Rand, Mary F. Feitosa, Mary K. Wojczynski, Lisa R. Yanek, Yaming Shao, Rebecca Rohde, Adebowale A. Adeyemo, Melinda C. Aldrich, Matthew A. Allison, Christine B. Ambrosone, Stefan Ambs, Christopher Amos, Donna K. Arnett, Larry Atwood, Elisa Bandera, Traci Bartz, Diane M. Becker, Sonja Berndt, Leslie Bernstein, Lawrence F. Bielak, William J. Blot, Erwin P. Bottinger, Donald W. Bowden, Jonathan P. Bradfield, Jennifer A. Brody, Ulrich Broeckel, Gregory Burke, Brian E. Cade, Qiuyin Cai, Neil Caporaso, Chris Carlson, John Carpten, Graham Casey, Stephen J. Chanock, Guanjie Chen, Minhui Chen, Yii-Der Chen, Wei-Min Chen, Alessandra Chesi, Charleston W. K. Chiang, Lisa Chu, Gerry A. Coetzee, David Conti, Richard S. Cooper, Mary Cushman, Ellen Demerath, Sandra L. Deming, Latchezar Dimitrov, Jingzhong Ding, W. Ryan Diver, Qing Duan, Michele K. Evans, Adeyinka G. Falusi, Jessica D. Faul, Myriam Fornage, Caroline Fox, Barry Freedman, Melissa Garcia, Elizabeth M. Gillanders, Phyllis Goodman, Omri Gottesman, Struan F. A. Grant, Xiuqing Guo, Hakon Hakonarson, Talin Haritunians, Tamara B. Harris, Curtis C. Harris, Brian E. Henderson, Anselm Hennis, Dena G. Hernandez, Joel N. Hirschhorn, Lorna Haughton McNeill, Timothy D. Howard, Barbara Howard, Ann W. Hsing, Yu-Han H. Hsu, Jennifer J. Hu, Chad D. Huff, Dezheng Huo, Sue A. Ingles, Marguerite R. Irvin, Esther M. John, Karen C. Johnson, Joanne M. Jordan, Edmond K. Kabagambe, Sun J. Kang, Sharon L. Kardia, Brendan J. Keating, Rick A. Kittles, Eric A. Klein, Suzanne Kolb, Laurence N. Kolonel, Charles Kooperberg, Lewis Kuller, Abdullah Kutlar, Leslie Lange, Carl D. Langefeld, Loic Le Marchand, Hampton Leonard, Guillaume Lettre, Albert M. Levin, Yun Li, Jin Li, Yongmei Liu, Youfang Liu, Simin Liu, Kurt Lohman, Vaneet Lotay, Yingchang Lu, William Maixner, JoAnn E. Manson, Barbara McKnight, Yan Meng, Keri L. Monda, Kris Monroe, Jason H. Moore, Thomas H. Mosley, Poorva Mudgal, Adam B. Murphy, Rajiv Nadukuru, Mike A. Nalls, Katherine L. Nathanson, Uma Nayak, Amidou N'Diaye, Barbara Nemesure, Christine Neslund-Dudas, Marian L. Neuhouser, Sarah Nyante, Heather Ochs-Balcom, Temidayo O. Ogundiran, Adesola Ogunniyi, Oladosu Ojengbede, Hayrettin Okut, Olufunmilayo Olopade, Andrew Olshan, Badri Padhukasahasram, Julie Palmer, Cameron D. Palmer, Nicholette D. Palmer, George Papanicolaou, Sanjay R. Patel, Curtis A. Pettaway, Patricia A. Peyser, Michael F. Press, D. C. Rao, Laura J. Rasmussen-Torvik, Susan Redline, Alex P. Reiner, Suhn K. Rhie, Jorge L. Rodriguez-Gil, Charles N. Rotimi, Jerome Rotter, Edward A. Ruiz-Narvaez, Benjamin A. Rybicki, Babatunde Salako, Michele M. Sale, Maureen Sanderson, Eric Schadt, Pamela J. Schreiner, Claudia Schurmann, Ann G. Schwartz, Daniel A. Shriner, Lisa B. Signorello, Andrew B. Singleton, David S. Siscovick, Jennifer A. Smith, Shad Smith, Elizabeth Speliotes, Margaret Spitz, Janet L. Stanford, Victoria L. Stevens, Alex Stram, Sara S. Strom, Lara Sucheston, Yan Sun, Salman M. Tajuddin, Herman Taylor, Kira Taylor, Bamidele O. Tayo, Michael J. Thun, Margaret A. Tucker, Dhananjay Vaidya, David J. Van den Berg, Sailaja Vedantam, Mara Vitolins, Zhaoming Wang, Erin B. Ware, Sylvia Wassertheil-Smoller, David R. Weir, John K. Wiencke, Scott M. Williams, L. Keoki Williams, James G. Wilson, John S. Witte, Margaret Wrensch, Xifeng Wu, Jie Yao, Neil Zakai, Krista Zanetti, Babette S. Zemel, Wei Zhao, Jing Hua Zhao, Wei Zheng, Degui Zhi, Jie Zhou, Xiaofeng Zhu, Regina G. Ziegler, Joe Zmuda, Alan B. Zonderman, Bruce M. Psaty, Ingrid B. Borecki, L. Adrienne Cupples, Ching-Ti Liu, Christopher A. Haiman, Ruth Loos, Maggie C. Y. Ng, Kari E. North
Summary: The study identified new height-related loci in African ancestry individuals and revealed additional signals by combining African and European GWAS data, improving the fine-mapping of potential causal variants shared between populations of African and European ancestry.
AMERICAN JOURNAL OF HUMAN GENETICS
(2021)
Article
Plant Sciences
Kassa Semagn, Muhammad Iqbal, Hua Chen, Enid Perez-Lara, Darcy H. Bemister, Rongrong Xiang, Jun Zou, Muhammad Asif, Atif Kamran, Amidou N'Diaye, Harpinder Randhawa, Curtis Pozniak, Dean Spaner
Summary: In this study, QTL associated with heading, flowering, and maturity time in four hard red spring wheat populations were mapped and characterized using the IWGSC RefSeq v2.0 physical map. A total of 44 QTL were identified, with 15 QTL common to both conventional and organic management systems, while the rest were specific to either system. Some QTL contain known genes that regulate important agronomic traits in wheat, providing a basis for further cloning and characterization.
Article
Plant Sciences
Firdissa E. Bokore, Richard D. Cuthbert, Colin W. Hiebert, Tom G. Fetch, Curtis J. Pozniak, Amidou N'Diaye, Yuefeng Ruan, Brad Meyer, Ron E. Knox
Summary: This study identified stable major and minor QTL associated with field stem rust resistance in 'AAC Prevail' and 'BW961MODIFIER LETTER PRIME', providing breeders with new information and markers to utilize these sources of stem rust resistance.
CANADIAN JOURNAL OF PLANT PATHOLOGY
(2021)
Article
Agronomy
Kassa Semagn, Muhammad Iqbal, Hua Chen, Enid Perez-Lara, Darcy H. Bemister, Rongrong Xiang, Jun Zou, Muhammad Asif, Atif Kamran, Amidou N'Diaye, Harpinder Randhawa, Brian L. Beres, Curtis Pozniak, Dean Spaner
Summary: This study identified 152 QTL and 22 QTL hotspots associated with nine agronomic and end-use quality traits in spring wheat populations. Two QTL with major effects were consistently detected in all environments, providing a strong foundation for further characterization and possibly cloning. The physical positions of these QTL offer valuable information for marker development and comparison across independent studies.
THEORETICAL AND APPLIED GENETICS
(2021)
Article
Agronomy
Kassa Semagn, Muhammad Iqbal, Jose Crossa, Diego Jarquin, Reka Howard, Hua Chen, Darcy H. Bemister, Brian L. Beres, Harpinder Randhawa, Amidou N'Diaye, Curtis Pozniak, Dean Spaner
Summary: This study utilized phenotype data from three spring wheat populations to assess prediction accuracies under organic and conventional management systems for seven traits. Results showed that phenotype data collected under organic management effectively predicted performance under conventional management, and vice versa, with high prediction accuracies observed.
THEORETICAL AND APPLIED GENETICS
(2022)
Article
Multidisciplinary Sciences
Kassa Semagn, Muhammad Iqbal, Nikolaos Alachiotis, Amidou N'Diaye, Curtis Pozniak, Dean Spaner
Summary: A study using a large number of markers assessed the genetic diversity of historical and modern Canadian spring wheat varieties, revealing a high proportion of allelic redundancy and a lack of clear structure or differentiation. Different wheat classes and predicted groups exhibit diverse levels of genetic divergence, with cultivars registered from 1970 to 1980 having the highest diversity indices and those registered from 2011 to 2018 having the lowest.
SCIENTIFIC REPORTS
(2021)
Article
Plant Sciences
Firdissa E. Bokore, Ron E. Knox, Colin W. Hiebert, Richard D. Cuthbert, Ron M. DePauw, Brad Meyer, Amidou N'Diaye, Curtis J. Pozniak, Brent D. McCallum
Summary: Carberry is a widely grown spring wheat cultivar in Canada with high level of leaf rust resistance. The genetic basis of Carberry's resistance includes multiple genes, such as Lr46 and Lr34. Despite the evolution of virulence in the pathogen population towards other resistance genes, Carberry's resistance remains effective.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Agronomy
Kassa Semagn, Muhammad Iqbal, Amidou N'Diaye, Curtis J. Pozniak, Izabela Ciechanowska, Steliana-Paula Barbu, Dean Spaner
Summary: This study used a panel of 192 spring wheat cultivars widely used in western Canada to explore allelic variation and effects of known genes, and identified genomic regions associated with agronomic traits using the IWGSC RefSeq v2.0 map.
Article
Agronomy
Firdissa E. Bokore, Richard D. Cuthbert, Ron E. Knox, Heather L. Campbell, Brad Meyer, Amidou N'Diaye, Curtis J. Pozniak, Ron DePauw
Summary: This study identified QTL associated with shattering resistance in wheat and analyzed the epistatic interactions between QTL. The results showed that QTL on chromosome arms 4BS and 5AL were associated with reduced shattering. These findings are important for understanding the inheritance of shattering resistance and developing wheat cultivars with shattering resistance.
THEORETICAL AND APPLIED GENETICS
(2022)
Article
Genetics & Heredity
Kassa Semagn, Muhammad Iqbal, Diego Jarquin, Jose Crossa, Reka Howard, Izabela Ciechanowska, Maria Antonia Henriquez, Harpinder Randhawa, Reem Aboukhaddour, Brent D. McCallum, Anita L. Brule-Babel, Alireza Navabi, Amidou N'Diaye, Curtis Pozniak, Dean Spaner
Summary: This study investigated the application of genomic selection in major diseases of spring wheat and compared the impact of different models on prediction accuracies. The results showed that the M3 model, which incorporated GE interactions, outperformed the M2 model in reducing residual variance and improving prediction accuracies.
Review
Agronomy
R. F. Park, W. H. P. Boshoff, A. L. Cabral, J. Chong, J. A. Martinelli, M. S. McMullen, J. W. Mitchell Fetch, E. Paczos-Grzeda, E. Prats, J. Roake, S. Sowa, L. Ziems, D. Singh
Summary: Crown rust, caused by Puccinia coronata f. sp. avenae (Pca), is a significant obstacle to oat production worldwide. Understanding the allelic relationships and chromosomal locations of resistance genes in oat is still limited. The high variability of Pca necessitates strategies to control the disease considering a large and diverse pathogen population. Pyramiding multiple resistance genes could enhance resistance levels.
THEORETICAL AND APPLIED GENETICS
(2022)
Article
Plant Sciences
Yunfei Jiang, Amidou N'Diaye, Chu Shin Koh, Teagen D. Quilichini, Arun S. K. Shunmugam, Morgan W. Kirzinger, David Konkin, Yasmina Bekkaoui, Ehsan Sari, Asher Pasha, Eddi Esteban, Nicholas J. Provart, James D. Higgins, Kevin Rozwadowski, Andrew G. Sharpe, Curtis J. Pozniak, Sateesh Kagale
Summary: By conducting a detailed transcriptome analysis in wheat, novel mechanisms of meiotic transcriptional regulation and meiosis-specific transcripts were revealed. These findings are important for improving recombination rates and genetic variation in crop plants, as well as for answering unresolved questions about meiosis. The study also provides a valuable resource of knowledge for those aiming to directly modulate meiosis in order to improve crop plants.
Article
Agronomy
Teketel A. Haile, Sean Walkowiak, Amidou N'Diaye, John M. Clarke, Pierre J. Hucl, Richard D. Cuthbert, Ron E. Knox, Curtis J. Pozniak
Summary: Genomic predictions within populations show moderate to high accuracies, while across-population genomic predictions in wheat with small population size should be approached with caution. BayesB model performs well in the presence of few QTL, and cross-validation design has a significant impact on prediction accuracy.
THEORETICAL AND APPLIED GENETICS
(2021)
