Article
Multidisciplinary Sciences
Tobias Weller, Max Eike Timm, Thomas Lenarz, Andreas Buechner
Summary: This study investigated the relationship between insertion angle and cochlear coverage of lateral wall electrode arrays and post-operative speech recognition scores. It found that higher cochlear coverage and insertion angle were correlated with better word recognition scores. These findings suggest that choosing the optimal electrode array can improve cochlear implantation outcomes.
Article
Otorhinolaryngology
Michael W. Canfarotta, Margaret T. Dillon, Kevin D. Brown, Harold C. Pillsbury, Matthew M. Dedmon, Brendan P. O'Connell
Summary: The study found that complete insertion of a 31.5-mm flexible array is feasible in most cases and is not limited by the range of cochlear duct length observed in the cohort. Future studies are needed to estimate other variations in cochlear morphology that could predict resistance and failure to achieve complete insertion with long arrays.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2021)
Review
Medicine, Research & Experimental
Saad Jwair, Adrianus Prins, Inge Wegner, Robert J. Stokroos, Huib Versnel, Hans G. X. M. Thomeer
Summary: This study compared lateral wall and perimodiolar arrays in cochlear implantation and found that lateral wall arrays had significantly lower rates of scalar translocation and less negative impact on speech perception scores. Perimodiolar arrays were more prone to tip fold-over, indicating that lateral wall arrays may be the preferred option for minimizing intracochlear trauma in cochlear implantation.
Article
Clinical Neurology
Joshua J. Sturm, Vir Patel, Greg Dibelius, Megan Kuhlmey, Ana H. Kim
Summary: The physical shape of cochlear implant arrays can impact hearing outcomes, with perimodiolar designs showing superior speech perception in the first 6 months post-implantation compared to lateral wall electrodes, and equalizing performance by 24 months. Perimodiolar arrays also demonstrate superior melody perception compared to lateral wall designs.
OTOLOGY & NEUROTOLOGY
(2021)
Article
Audiology & Speech-Language Pathology
Samuel Soderqvist, Satu Lamminmaki, Antti Aarnisalo, Timo Hirvonen, Saku T. Sinkkonen, Ville Sivonen
Summary: This study found a correlation between the spread of intracochlear electrical field and neural excitation in cochlear implant technology, with larger cochleae associated with more focused spread.
Article
Multidisciplinary Sciences
Ben Somers, Christopher J. Long, Tom Francart
Summary: Cochlear implants are successful medical prostheses that help deaf individuals hear again by stimulating the auditory nerve. The fitting process, based on subjective feedback, can be time-consuming and challenging, as it relies on infrequent clinic sessions for adjustments. Objective audiometry offers a solution by analyzing brain responses to auditory stimulation, but still requires costly equipment. Recording neural signals using the implant itself shows promise for chronic neuro-monitoring of hearing-impaired patients and neuro-steered hearing prostheses.
SCIENTIFIC REPORTS
(2021)
Article
Neurosciences
Maria Huber
Summary: Cochlear implants (CIs) are electronic medical devices that may pose specific risks and burdens for young CI users, such as medical and device-related complications, lifelong dependence on the implanted device, and neurosecurity risks. These risks and burdens can affect their quality of life.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Clinical Neurology
Rolf Salcher, Aaron Boruchov, Max Timm, Melanie Steffens, Anja Giesemann, Thomas Lenarz, Athanasia Warnecke
Summary: The study utilized a retrospective analysis of patient data sets to examine the position of electrode arrays within the cochlea. Coating electrode contacts with swelling hydrogels proved effective in bridging the gap between the electrode array and the cochlear wall, facilitating focused electrical stimulation of individual spiral ganglion neurons. While there were no significant differences in the distances from each electrode contact to the cochlear walls within each patient, there were significant variations between different contacts within the same patient.
OTOLOGY & NEUROTOLOGY
(2021)
Article
Psychology, Multidisciplinary
Yang-Soo Yoon, Carrie Drew
Summary: This study aimed to investigate whether bilateral cochlear implant (BCI) and bilateral hearing aid (BHA) users experienced similar enhancement on consonant recognition with intensified spectral and temporal cues. The results showed that the intensified frequency and time ranges contributed to consonant enhancement for both monaural and binaural listening and both BCI and BHA technologies. However, the intensified ranges did not significantly improve the binaural benefit.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Audiology & Speech-Language Pathology
Simon Konrad, Andreas Buechner, Thomas Lenarz, Gerrit Paasche
Summary: This study aimed to evaluate impedance development after implantation of Hybrid-L electrodes. The results showed that despite smaller contacts, impedance values after electrical stimulation were comparable to published values of Contour electrodes, indicating less tissue growth with the Hybrid-L electrode array.
INTERNATIONAL JOURNAL OF AUDIOLOGY
(2022)
Article
Otorhinolaryngology
Nicholas Bevis, Thomas Effertz, Dirk Beutner, Christian Gueldner
Summary: CBCT offers a potential reduction in radiation dose for postoperative imaging of cochlear implants, with Contour Advance CIs positioned closer to the modiolus compared to Straight CIs. The increase in artifact portion from base to apex of the cochlea limits visualization of electrodes in the middle and apical portions.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2021)
Article
Clinical Neurology
Geonho Lee, Seulgi Lee, Jee-Hye Chung, Jin Woong Choi
Summary: The study evaluated the outcomes and association factors of long-term hearing preservation in cochlear implantation with lateral wall electrode arrays. The results showed that with lateral wall electrode arrays, 68% of HEARRRING group patients and 41% of functional classification patients achieved hearing preservation. A preimplant pure-tone threshold of <= 60 dB HL at 250 Hz was significantly associated with an increased rate of long-term hearing preservation.
OTOLOGY & NEUROTOLOGY
(2021)
Review
Audiology & Speech-Language Pathology
Tom Gajecki, Waldo Nogueira
Summary: Enhancing interaural level differences (ILDs) coding can improve sound localization accuracy for bilateral cochlear implant (BiCI) users, especially at narrow azimuths. Additionally, linking band selection can enhance left/right discrimination accuracy at larger azimuths, benefiting some BiCI participants.
Article
Engineering, Biomedical
Karolin Wey, Ronja Schirrmann, Detlef Diesing, Stephan Lang, Sven Brandau, Stefan Hansen, Matthias Epple
Summary: Loading nucleic acids into calcium phosphate nanoparticles and coating them on inner-ear cochlear implant electrodes enhances the growth of spiral ganglion cell axons for improved electrical pulse transmission.
Article
Engineering, Biomedical
Nina Aldag, Andreas Buechner, Thomas Lenarz, Waldo Nogueira
Summary: This study investigates the feasibility of using electrodes and backward telemetry of cochlear implants (CIs) to record electroencephalography (EEG). It shows that single-channel EEG is suitable for auditory selective attention decoding, although its decoding quality is reduced compared to a multi-channel approach. CI-based implant-based EEG (iEEG) can be used for recording cortical auditory evoked potentials (CAEP) and decoding selective attention.
JOURNAL OF NEURAL ENGINEERING
(2022)
Article
Computer Science, Interdisciplinary Applications
Daniel Schurzig, Sebastian Schwarzendahl, Joerg Wallaschek, Wouter J. van Drunen, Thomas S. Rau, Thomas Lenarz, Omid Majdani
MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING
(2018)
Article
Audiology & Speech-Language Pathology
Mareike Buhl, Anna Warzybok, Marc Rene Schaedler, Thomas Lenarz, Omid Majdani, Birger Kollmeier
INTERNATIONAL JOURNAL OF AUDIOLOGY
(2019)
Article
Engineering, Biomedical
Samuel Mueller, Lueder A. Kahrs, Johannes Gaa, Sebastian Tauscher, Marcel Kluge, Samuel John, Thomas S. Rau, Thomas Lenarz, Tobias Ortmaier, Omid Majdani
INTERNATIONAL JOURNAL OF COMPUTER ASSISTED RADIOLOGY AND SURGERY
(2019)
Article
Engineering, Biomedical
Thomas S. Rau, Diana Kreul, Jakob Lexow, Silke Huegl, M. Geraldine Zuniga, Thomas Lenarz, Omid Majdani
COMPUTERIZED MEDICAL IMAGING AND GRAPHICS
(2019)
Article
Clinical Neurology
Freddi Zelener, Omid Majdani, Ariane Roemer, G. Jakob Lexow, Anja Giesemann, Thomas Lenarz, Athanasia Warnecke
OTOLOGY & NEUROTOLOGY
(2020)
Article
Audiology & Speech-Language Pathology
Mareike Buhl, Anna Warzybok, Marc Rene Schaedler, Omid Majdani, Birger Kollmeier
INTERNATIONAL JOURNAL OF AUDIOLOGY
(2020)
Article
Clinical Neurology
Nils K. Prenzler, Tobias Weller, Melanie Steffens, Anke Lesinski-Schiedat, Andreas Buechner, Thomas Lenarz, Athanasia Warnecke
OTOLOGY & NEUROTOLOGY
(2020)
Article
Audiology & Speech-Language Pathology
Daniel Schurzig, Max E. Timm, Omid Majdani, Thomas Lenarz, Thomas S. Rau
Summary: The study assessed variations in human intracochlear anatomy and factors relevant to cochlear implantation, finding significant anatomical variability in the round window region. The study concluded that while there is generally enough space within the ST for CI, flexible surgical techniques and implant designs are important due to strong intracochlear anatomical variations. Cochlear dimensions, especially at the round window, could potentially indicate surgically challenging anatomies.
Article
Engineering, Biomedical
Thomas S. Rau, Tim Ehmann, M. Geraldine Zuniga, Katarzyna Plaskonka, Andreas Keck, Omid Majdani, Thomas Lenarz
Summary: This study presents a prototype of an electrode array for cochlear implants that utilizes a shape memory effect to shift the array towards the inner wall of the cochlea. By adjusting the properties of Nitinol and implementing a suitable cooling strategy, the array can be gently inserted into an artificial cochlear model. The results demonstrate the feasibility of using the body temperature responsive shape memory effect for perimodiolar electrode array positioning.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
(2022)
Article
Engineering, Biomedical
Thomas S. Rau, Samuel John, Marcel Kluge, Felix Repp, M. Geraldine Zuniga, Jan Stieghorst, Max E. Timm, Max Froehlich, Omid Majdani, Thomas Lenarz
Summary: This article describes a new micro-stereotactic targeting system designed for cochlear implant surgery and its evaluation in an ex vivo study. The system demonstrated successful performance of minimally invasive posterior tympanotomy in all specimens.
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
(2023)
Article
Otorhinolaryngology
Lena Geiger, M. Geraldine Zuniga, Thomas Lenarz, Omid Majdani, Thomas S. Rau
Summary: This study aims to perform minimally invasive cochlear implant surgery using a micro-stereotactic surgical targeting system with on-site moulding of the template. The accuracy of the system was evaluated through ex-vivo testing on cadaveric temporal bone specimens. The results showed a high success rate of the surgery and suitability for various applications.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2023)
Article
Clinical Neurology
Daniel Sieber, Max E. Timm, Tobias Weller, Marie Suhling, Thomas Lenarz, Daniel Schurzig
Summary: Assessment techniques for the cochlear spatial lateral wall show variations between methods, observers, and imaging modalities. However, they still contribute to optimized electrode selection based on individual patient anatomy.
OTOLOGY & NEUROTOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Thomas S. Rau, Sina Witte, Lea Uhlenbusch, Luder A. Kahrs, Thomas Lenarz, Omid Majdani
Summary: The study introduces a concept for customizable guidance instrument in surgical procedures, utilizing bone cement to fabricate individualized surgical templates. Experimental results demonstrate high positioning accuracy and drilling precision, providing an easy-to-use and sterile approach with promising accuracy for surgical applications such as neurosurgery.
JOURNAL OF MEDICAL IMAGING
(2021)
Article
Otorhinolaryngology
Elham Majdani, Omid Majdani, Melanie Steffens, Athanasia Warnecke, Anke Lesinski-Schiedat, Thomas Lenarz, Friedrich Goetz
COCHLEAR IMPLANTS INTERNATIONAL
(2020)