- Home
- Publications
- Publication Search
- Publication Details
Title
Reversible covalent direct thrombin inhibitors
Authors
Keywords
Thrombin, Serine proteases, Blood plasma, Enzyme inhibitors, Anticoagulants, Crystal structure, Fibrinogen, Plasmins
Journal
PLoS One
Volume 13, Issue 8, Pages e0201377
Publisher
Public Library of Science (PLoS)
Online
2018-08-03
DOI
10.1371/journal.pone.0201377
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Risk of Bleeding With Dabigatran in Atrial Fibrillation
- (2015) Inmaculada Hernandez et al. JAMA Internal Medicine
- How good are my data and what is the resolution?
- (2013) Philip R. Evans et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- 1,2,4-Triazole derivatives as transient inactivators of kallikreins involved in skin diseases
- (2013) Xiao Tan et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Drug discovery considerations in the development of covalent inhibitors
- (2013) Robert Mah et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- The New Oral Anticoagulants in Clinical Practice
- (2013) Wilson I. Gonsalves et al. MAYO CLINIC PROCEEDINGS
- Gastrointestinal bleeding with the new oral anticoagulants – defining the issues and the management strategies
- (2013) Jay Desai et al. THROMBOSIS AND HAEMOSTASIS
- Oral Direct Factor Xa Inhibitors
- (2012) Calvin H. Yeh et al. CIRCULATION RESEARCH
- REFMAC5 for the refinement of macromolecular crystal structures
- (2011) Garib N. Murshudov et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Crystal Structures of Prethrombin-2 Reveal Alternative Conformations under Identical Solution Conditions and the Mechanism of Zymogen Activation
- (2011) Nicola Pozzi et al. BIOCHEMISTRY
- Direct thrombin inhibitors
- (2011) Catherine J. Lee et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- The resurgence of covalent drugs
- (2011) Juswinder Singh et al. NATURE REVIEWS DRUG DISCOVERY
- XDS
- (2010) Wolfgang Kabsch ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Strategies for discovering and derisking covalent, irreversible enzyme inhibitors
- (2010) Douglas S Johnson et al. Future Medicinal Chemistry
- Crystallographic determination of the structures of human α-thrombin complexed with BMS-186282 and BMS-189090
- (2010) Mary F. Malley et al. PROTEIN SCIENCE
- Is thrombin generation the new rapid, reliable and relevant pharmacological tool for the development of anticoagulant drugs?
- (2008) Séverine Robert et al. PHARMACOLOGICAL RESEARCH
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started