Truncations of the titin Z-disc predispose to a heart failure with preserved ejection phenotype in the context of pressure overload
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Title
Truncations of the titin Z-disc predispose to a heart failure with preserved ejection phenotype in the context of pressure overload
Authors
Keywords
Apoptosis, Fibrosis, Collagens, Heart, Echocardiography, Myocardium, Protein expression, Common carotid arteries
Journal
PLoS One
Volume 13, Issue 7, Pages e0201498
Publisher
Public Library of Science (PLoS)
Online
2018-08-01
DOI
10.1371/journal.pone.0201498
References
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Note: Only part of the references are listed.- Titin-truncating variants affect heart function in disease cohorts and the general population
- (2016) Sebastian Schafer et al. NATURE GENETICS
- Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy
- (2015) J. T. Hinson et al. SCIENCE
- Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease
- (2015) Angharad M. Roberts et al. Science Translational Medicine
- Pressure Overload by Transverse Aortic Constriction Induces Maladaptive Hypertrophy in a Titin-Truncated Mouse Model
- (2015) Qifeng Zhou et al. Biomed Research International
- Cardiac Repair in a Porcine Model of Acute Myocardial Infarction with Human Induced Pluripotent Stem Cell-Derived Cardiovascular Cells
- (2014) Lei Ye et al. Cell Stem Cell
- Deletion of the titin N2B region accelerates myofibrillar force development but does not alter relaxation kinetics
- (2014) F. Elhamine et al. JOURNAL OF CELL SCIENCE
- Deleting titin’s I-band/A-band junction reveals critical roles for titin in biomechanical sensing and cardiac function
- (2014) Henk L. Granzier et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pathological Ventricular Remodeling
- (2013) Min Xie et al. CIRCULATION
- Thymosin 4 Increases the Potency of Transplanted Mesenchymal Stem Cells for Myocardial Repair
- (2013) L. Ye et al. CIRCULATION
- Pathological Ventricular Remodeling
- (2013) Jana S. Burchfield et al. CIRCULATION
- Skeletal myoblast transplantation on gene expression profiles of insulin signaling pathway and mitochondrial biogenesis and function in skeletal muscle
- (2013) Jian-Hua Ma et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Variable phenotype in murine transverse aortic constriction
- (2011) Selma F. Mohammed et al. CARDIOVASCULAR PATHOLOGY
- Nuclear Factor Kappa B and Matrix Metalloproteinase Induced Receptor Cleavage in the Spontaneously Hypertensive Rat
- (2011) Kwan-I Sharon Wu et al. HYPERTENSION
- Cardiac Z-disc Signaling Network
- (2011) Derk Frank et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Apoptosis in severe, compensated pressure overload predominates in nonmyocytes and is related to the hypertrophy but not function
- (2010) Ricardo J. Gelpi et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Cardiac Inflammation Contributes to Changes in the Extracellular Matrix in Patients With Heart Failure and Normal Ejection Fraction
- (2010) Dirk Westermann et al. Circulation-Heart Failure
- Enhanced Matrix Metalloproteinase Activity in the Spontaneously Hypertensive Rat: VEGFR-2 Cleavage, Endothelial Apoptosis, and Capillary Rarefaction
- (2010) Edward D. Tran et al. JOURNAL OF VASCULAR RESEARCH
- Apoptosis predominates in nonmyocytes in heart failure
- (2009) Misun Park et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Periostin Is a Novel Factor in Cardiac Remodeling After Experimental and Clinical Unloading of the Failing Heart
- (2009) William E. Stansfield et al. ANNALS OF THORACIC SURGERY
- NF- B activation is required for adaptive cardiac hypertrophy
- (2009) L. Zelarayan et al. CARDIOVASCULAR RESEARCH
- Influence of Myocardial Fibrosis on Left Ventricular Diastolic Function
- (2009) Antonella Moreo et al. Circulation-Cardiovascular Imaging
- Skeletal myoblast transplantation for attenuation of hyperglycaemia, hyperinsulinaemia and glucose intolerance in a mouse model of type 2 diabetes mellitus
- (2009) L. Ye et al. DIABETOLOGIA
- Stress-induced dilated cardiomyopathy in a knock-in mouse model mimicking human titin-based disease
- (2009) Michael Gramlich et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Regression of pressure-induced left ventricular hypertrophy is characterized by a distinct gene expression profile
- (2009) William E. Stansfield et al. JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
- Measurement of cardiac function using pressure–volume conductance catheter technique in mice and rats
- (2008) Pál Pacher et al. Nature Protocols
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