Low-volume goat milk transmission of classical scrapie to lambs and goat kids

Goats singly heterozygous for PRNP S146 or K222 orally inoculated with classical scrapie at birth show no disease at ages well beyond 6 years

(2018) M.U. Cinar et al.   VETERINARY JOURNAL

Classical scrapie prions are associated with peripheral blood monocytes and T-lymphocytes from naturally infected sheep

(2016) Rohana P. Dassanayake et al.   BMC Veterinary Research

Evidence of scrapie transmission to sheep via goat milk

(2016) Timm Konold et al.   BMC Veterinary Research

Role of thePRNPS127 allele in experimental infection of goats with classical caprine scrapie

(2015) Rohana P. Dassanayake et al.   ANIMAL GENETICS

The placenta shed from goats with classical scrapie is infectious to goat kids and lambs

(2015) David A. Schneider et al.   JOURNAL OF GENERAL VIROLOGY

PRNP variants in goats reduce sensitivity of detection of PrPSc by immunoassay

(2015) Sally A. Madsen-Bouterse et al.   JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION

Classical natural ovine scrapie prions detected in practical volumes of blood by lamb and transgenic mouse bioassays

(2015) Rohana P. Dassanayake et al.   Journal of Veterinary Science

Novel polymorphisms in ovineprion proteingene

(2013) H. Meydan et al.   ANIMAL GENETICS

Evidence of effective scrapie transmission via colostrum and milk in sheep

(2013) Timm Konold et al.   BMC Veterinary Research

Genetic Resistance to Scrapie Infection in Experimentally Challenged Goats

(2013) C. Lacroux et al.   JOURNAL OF VIROLOGY

Towards further reduction and replacement of animal bioassays in prion research by cell and protein misfolding cyclic amplification assays

(2013) Susann Boerner et al.   LABORATORY ANIMALS

Variation in udder health indicators at different stages of lactation in goats with no udder infection

(2013) Ylva Persson et al.   SMALL RUMINANT RESEARCH

Transmission of classical scrapie via goat milk

(2013) Timm Konold et al.   VETERINARY RECORD

Differential immunoreactivity of goat derived scrapie following in vitro misfolding versus mouse bioassay

(2012) Sally A. Madsen-Bouterse et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Transmissible Proteins: Expanding the Prion Heresy

(2012) Claudio Soto   CELL

Extended scrapie incubation time in goats singly heterozygous for PRNP S146 or K222

(2012) Stephen N. White et al.   GENE

Protein misfolding cyclic amplification of infectious prions

(2012) Rodrigo Morales et al.   Nature Protocols

Fast and ultrasensitive method for quantitating prion infectivity titre

(2012) Natallia Makarava et al.   Nature Communications

Sparse PrPSc accumulation in the placentas of goats with naturally acquired scrapie

(2011) Katherine I O'Rourke et al.   BMC Veterinary Research

Diagnostic Assays Used to Control Small Ruminant Lentiviruses

(2011) Lynn M. Herrmann-Hoesing   JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION

Monitoring of clinical signs in goats with transmissible spongiform encephalopathies

(2010) Timm Konold et al.   BMC Veterinary Research

Sheep with Scrapie and Mastitis Transmit Infectious Prions through the Milk

(2010) C. Ligios et al.   JOURNAL OF VIROLOGY

In vitro amplification of prions from milk in the detection of subclinical infections

(2010) Kevin C. Gough et al.   Prion

The effects of storage temperature on goat milk somatic cell count using the DeLaval counter

(2010) Davinia Sanchez-Macias et al.   TROPICAL ANIMAL HEALTH AND PRODUCTION

An assessment of the efficiency of PrPsc detection in rectal mucosa and third-eyelid biopsies from animals infected with scrapie

(2010) Eva Monleón et al.   VETERINARY MICROBIOLOGY

Diagnosis of preclinical scrapie in live sheep by the immunohistochemical examination of rectal biopsies

(2010) L. Gonzalez et al.   VETERINARY RECORD

Pathogenesis of natural goat scrapie: modulation by hostPRNPgenotype and effect of co-existent conditions

(2010) Lorenzo González et al.   VETERINARY RESEARCH

Detection of PrPScin lung and mammary gland is favored by the presence of Visna/maedi virus lesions in naturally coinfected sheep

(2010) Eider Salazar et al.   VETERINARY RESEARCH

Prions Are Secreted in Milk from Clinically Normal Scrapie-Exposed Sheep

(2009) B. C. Maddison et al.   JOURNAL OF VIROLOGY

High prevalence of scrapie in a dairy goat herd: tissue distribution of disease-associated PrP and effect ofPRNPgenotype and age

(2009) Lorenzo González et al.   VETERINARY RESEARCH

Evidence of scrapie transmission via milk

(2008) Timm Konold et al.   BMC Veterinary Research

In vitro amplification of PrPSc derived from the brain and blood of sheep infected with scrapie

(2008) L. Thorne et al.   JOURNAL OF GENERAL VIROLOGY

Small-Ruminant Lentivirus Enhances PrPSc Accumulation in Cultured Sheep Microglial Cells

(2008) J. B. Stanton et al.   JOURNAL OF VIROLOGY

Prions in Milk from Ewes Incubating Natural Scrapie

(2008) Caroline Lacroux et al.   PLoS Pathogens