Adenovirus platform enhances transduction efficiency of human mesenchymal stem cells: An opportunity for cellular carriers of targeted TRAIL-based TR3 biologics in ovarian cancer

Cancer statistics, 2016

(2016) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Membrane-proximal TRAIL species are incapable of inducing short circuit apoptosis signaling: Implications for drug development and basic cytokine biology

(2016) Katharina Tatzel et al.   Scientific Reports

Novel treatment option for MUC16-positive malignancies with the targeted TRAIL-based fusion protein Meso-TR3

(2014) Gunjal Garg et al.   BMC CANCER

Applying Synthetic Lethality for the Selective Targeting of Cancer

(2014) Donal P. McLornan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Systemic but not topical TRAIL-expressing mesenchymal stem cells reduce tumour growth in malignant mesothelioma

(2014) Elizabeth K Sage et al.   THORAX

An Adenovirus Vector Incorporating Carbohydrate Binding Domains Utilizes Glycans for Gene Transfer

(2013) Julius W. Kim et al.   PLoS One

Delivery of sTRAIL variants by MSCs in combination with cytotoxic drug treatment leads to p53-independent enhanced antitumor effects

(2013) R Yu et al.   Cell Death & Disease

TRAIL-engineered pancreas-derived mesenchymal stem cells: characterization and cytotoxic effects on pancreatic cancer cells

(2012) M R Moniri et al.   CANCER GENE THERAPY

Complete Regression of Metastatic Renal Cell Carcinoma by Multiple Injections of Engineered Mesenchymal Stem Cells Expressing Dodecameric TRAIL and HSV-TK

(2012) S. W. Kim et al.   CLINICAL CANCER RESEARCH

Stem Cell Implants for Cancer Therapy: TRAIL-Expressing Mesenchymal Stem Cells Target Cancer CellsIn Situ

(2012) Michaela R. Reagan et al.   Journal of Breast Cancer

Concise Review: Mesenchymal Stem Cell Tumor-Homing: Detection Methods in Disease Model Systems

(2011) Michaela R. Reagan et al.   STEM CELLS

TRAIL-expressing mesenchymal stem cells kill the putative cancer stem cell population

(2010) M R Loebinger et al.   BRITISH JOURNAL OF CANCER

Platelet Lysate Consisting of a Natural Repair Proteome Supports Human Mesenchymal Stem Cell Proliferation and Chromosomal Stability

(2010) Ruben Crespo-Diaz et al.   CELL TRANSPLANTATION

Branched oligomerization of cell-permeable peptides markedly enhances the transduction efficiency of adenovirus into mesenchymal stem cells

(2010) S-H Park et al.   GENE THERAPY

A Genetically Encoded Multifunctional TRAIL Trimer Facilitates Cell-Specific Targeting and Tumor Cell Killing

(2010) D. Spitzer et al.   MOLECULAR CANCER THERAPEUTICS

Therapeutic efficacy and safety of TRAIL-producing human adipose tissue-derived mesenchymal stem cells against experimental brainstem glioma

(2010) S. A. Choi et al.   NEURO-ONCOLOGY

Mesenchymal Stem Cell Delivery of TRAIL Can Eliminate Metastatic Cancer

(2009) M. R. Loebinger et al.   CANCER RESEARCH

TRAIL Gene Therapy: From Preclinical Development to Clinical Application

(2009) Thomas Griffith et al.   CURRENT GENE THERAPY

Growth inhibition of colorectal carcinoma by lentiviral TRAIL-transgenic human mesenchymal stem cells requires their substantial intratumoral presence

(2009) Jana Luetzkendorf et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy

(2009) L. S. Sasportas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Bone Marrow-Derived Mesenchymal Stromal Cells Expressing S-TRAIL as a Cellular Delivery Vehicle for Human Glioma Therapy

(2009) Lata G. Menon et al.   STEM CELLS

Gene Therapy Using TRAIL-Secreting Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells against Intracranial Glioma

(2008) S. M. Kim et al.   CANCER RESEARCH

Mesenchymal stem cells expressing TRAIL lead to tumour growth inhibition in an experimental lung cancer model

(2008) Andrea Mohr et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE