Article
Multidisciplinary Sciences
Ella Nissan, Uri Amit, Leo Baron, Amit Zabatani, Damien Urban, Iris Barshack, Tima Davidson
Summary: In this study, the role of [18F]FDG-PET/CT in identifying and managing cancer of unknown primary site (CUP syndrome) was assessed. Results showed a relatively good effectiveness of [18F]FDG-PET/CT in detecting primary tumors, especially in non-SCC type patients. However, the detection rate was lower in SCC patients. Additionally, [18F]FDG-PET/CT had a positive impact on the clinical management of patients with discovered primary tumors.
SCIENTIFIC REPORTS
(2021)
Review
Oncology
Emily W. Avery, Kavita Joshi, Saral Mehra, Amit Mahajan
Summary: Oropharyngeal squamous cell carcinoma (OPSCC) includes cancers in the tonsils, tongue base, soft palate, and uvula. Staging depends on the presence or absence of human papillomavirus (HPV)-directed pathogenesis. The incidence of HPV-associated oropharyngeal cancer (HPV + OPSCC) is expected to increase in the future. PET/CT is a valuable tool for diagnosing, staging, and monitoring patients with oropharyngeal cancers undergoing treatment and surveillance.
Article
Oncology
Qian Zhang, Xiuli Tao, Pei Yuan, Zewei Zhang, Jianming Ying, Lei Guo, Ning Li, Shuhang Wang, Jing Li, Ying Liu, Wei Guo, Shijun Zhao, Ning Wu
Summary: For patients with non-small cell lung cancer, metabolic parameters and serum tumor markers can predict the tumor mutational burden level, serving as potential alternatives for guiding immunotherapy.
Article
Radiology, Nuclear Medicine & Medical Imaging
Reiko Nakajima, Snehal G. Patel, Nora Katabi, Stephanie Flukes, Audrey Mauguen, Ian Ganly, Heiko Schoder
Summary: The study investigated the role of FDG PET/CT in evaluating recurrent salivary gland tumors, finding that FDG PET/CT is important in defining the extent of disease and providing prognostic information. It also identified total body metabolic tumor volume and total lesion glycolysis as independent prognostic factors for progression-free survival and overall survival.
AMERICAN JOURNAL OF ROENTGENOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Xiao-Yan Sun, Tian-Xiang Chen, Cheng Chang, Hao-Hua Teng, Chun Xie, Mao-Mei Ruan, Bei Lei, Liu Liu, Li-Hua Wang, Yun-Hai Yang, Wen-Hui Xie
Summary: The study demonstrated that the SUVmax value can predict the pathological subtype and histological grade of lung adenocarcinoma, with different tumor grades having distinct SUVmax cut-off values, and this conclusion was verified through validation experiments.
ACADEMIC RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jun Wen, Yinjie Zhu, Lianghua Li, Jianjun Liu, Yumei Chen, Ruohua Chen
Summary: Dynamic total-body PET imaging in patients with prostate cancer showed that 6 minutes post-injection was the optimal time for imaging, avoiding interference from bladder activity and detecting lesions with relatively low PSMA uptake. Additionally, imaging at 35-59 minutes post-injection could also yield similar results to imaging at 60 minutes post-injection.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2022)
Article
Oncology
Songbo Zhao, Yangang Bi, Zhenfang Wang, Fantao Zhang, Yang Zhang, Yongyun Xu
Summary: This study evaluated the diagnostic accuracy of single gastroscopy, multi-slice spiral CT, HER-2 or tumor markers, and their combination in the diagnosis of gastric cancer. The results showed that the combined diagnosis had higher sensitivity, specificity, and accuracy compared to single diagnosis, and it could more accurately determine the clinical staging and lesion invasion depth of gastric cancer.
WORLD JOURNAL OF SURGICAL ONCOLOGY
(2022)
Article
Oncology
Jianhao Qiu, Rongyang Li, Yukai Wang, Xiuyuan Ma, Chenghao Qu, Binyan Liu, Weiming Yue, Hui Tian
Summary: This study retrospectively analyzed data from 1064 patients with pulmonary nodules and successfully predicted high-risk pulmonary nodules using a predictive model and dynamic web nomogram. Accurate treatment for high-risk pulmonary nodules was achieved, promoting rapid recovery for patients.
FRONTIERS IN ONCOLOGY
(2023)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Huipan Liu, Xiao Yang, Dongmei Fan, Taiyong Lv, Yue Chen
Summary: Inflammatory myofibroblastic tumor is a rare mesenchymal neoplasm that can be found in various anatomical regions. This case report presents the Ga-68-FAPI PET/CT findings in a 49-year-old man with mesenteric inflammatory myofibroblastic tumor.
CLINICAL NUCLEAR MEDICINE
(2021)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Xilan Yao, Xiaohong Ou
Summary: A 50-year-old man presented with right chest pain and increased parathyroid hormone levels after parathyroidectomy. PET/CT scans revealed an osteolytic lesion on the right sixth rib, which was confirmed to be a brown tumor upon subsequent biopsy.
CLINICAL NUCLEAR MEDICINE
(2022)
Article
Biology
Xuan Wang, Layla Parast, Larry Han, Lu Tian, Tianxi Cai
Summary: Identifying effective surrogate markers is crucial for improving clinical trial efficiency. Replacing long-term outcomes with shorter-term and/or cheaper surrogate markers can shorten study duration and reduce costs. However, methods for combining multiple markers to construct a composite marker with improved surrogacy are limited.
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Filippo Lococo, Vittoria Rufini, Angelina Filice, Massimiliano Paci, Guido Rindi
Summary: SFTPs are rare mesenchymal tumors with difficult preoperative diagnosis. Ga-68-DOTATOC PET/CT imaging can aid in diagnosing SFTP and potentially offer new treatment options in unresectable or metastatic disease.
CLINICAL NUCLEAR MEDICINE
(2021)
Editorial Material
Medicine, General & Internal
Ryogo Minamimoto
Summary: Salivary gland tumors are rare neoplasms with varied origins and malignant potential. While FDG-PET has limited ability to differentiate between different types of salivary gland tumors, 4DST PET can provide more accurate characterization based on the proliferation of cells within the tumors.
Article
Oncology
Haiqing Chen, Fangqiu Fu, Yue Zhao, Haoxuan Wu, Hong Hu, Yihua Sun, Yawei Zhang, Jiaqing Xiang, Yang Zhang
Summary: The study revealed a significant association between serum tumor markers and recurrence risk in non-small cell lung cancer patients. Different types of tumor markers showed varying prognostic value in different subtypes of lung cancer.
FRONTIERS IN ONCOLOGY
(2021)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Guohua Shen, Rang Wang, Lili Pan, Anren Kuang
Summary: Glomus tumors are vascular neoplasms arising from glomus bodies, typically found in tissues concentrated with these bodies. We reported the MRI and FDG PET/CT findings of a glomus tumor presenting as an axillary mass in a 25-year-old woman.
CLINICAL NUCLEAR MEDICINE
(2021)