Article
Public, Environmental & Occupational Health
Binur Orazumbekova, Alpamys Issanov, Kuralay Atageldiyeva, Salim Berkinbayev, Gulnara Junusbekova, Laura Danyarova, Zhanmedet Shyman, Akmaral Tashmanova, Antonio Sarria-Santamera
Summary: This study aimed to estimate the prevalence of impaired fasting glucose (IFG), undiagnosed, and prior-diagnosed Type 2 diabetes mellitus (T2DM) in Kazakhstan. The results showed a high prevalence of IFG and a significant proportion of newly diagnosed T2DM in Kazakhstan. The identified risk factors can be used to strengthen the identification of undiagnosed patients and provide preventive or therapeutic interventions to reduce the incidence of T2DM and its complications.
FRONTIERS IN PUBLIC HEALTH
(2022)
Review
Clinical Neurology
Yuhan Karida Liu, Susan Ling, Leanna M. W. Lui, Felicia Ceban, Maj Vinberg, Lars Vedel Kessing, Roger C. Ho, Taeho Greg Rhee, Hartej Gill, Bing Cao, Rodrigo B. Mansur, Yena Lee, Joshua Rosenblat, Kayla M. Teopiz, Roger S. McIntyre
Summary: This study assessed the prevalence of type 2 diabetes, impaired fasting glucose, general obesity, and abdominal obesity in patients with bipolar disorder. The findings showed that patients with bipolar disorder had a higher prevalence of these conditions compared to the control group.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Endocrinology & Metabolism
Kara L. Holloway-Kew, Amelia Betson, Pamela G. Rufus-Membere, James Gaston, Adolfo Diez-Perez, Mark A. Kotowicz, Julie A. Pasco
Summary: This study found that in men, individuals with T2DM had lower bone material strength index (BMSi) compared to those without T2DM, independent of T2DM, while bone mineral density (BMD) and trabecular bone score (TBS) measured by DXA were higher. These results suggest that measures reflecting bone material properties and microarchitecture may be better than BMD in identifying individuals with T2DM at risk of fracture.
Article
Endocrinology & Metabolism
Mee Kyoung Kim, Kyungdo Han, Eun Sil Koh, Oak-Kee Hong, Ki-Hyun Baek, Ki-Ho Song, Hyuk-Sang Kwon
Summary: The status of metabolic abnormalities, including impaired fasting glucose (IFG), can change over time. Using data from the Korean National Health Insurance system, the study found that cumulative exposure to IFG was associated with a higher risk of type 2 diabetes mellitus in a dose-response fashion.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2021)
Article
Endocrinology & Metabolism
Qiuhong Gong, Ping Zhang, Jinping Wang, Edward W. Gregg, Yiling J. Cheng, Guangwei Li, Peter H. Bennett
Summary: This study found that lifestyle intervention can reduce the incidence of type 2 diabetes in individuals with impaired glucose tolerance, regardless of their baseline fasting plasma glucose levels. Additionally, in those with FPG <100 mg/dL, lifestyle intervention led to a significant delay in the onset of diabetes.
DIABETES OBESITY & METABOLISM
(2021)
Article
Biochemistry & Molecular Biology
Tina Kalbitzer, Kristina Lobenhofer, Silke Martin, Markus Beck Erlach, Werner Kremer, Hans Robert Kalbitzer
Summary: Type 2 diabetes and its borderline states, impaired fasting glucose and/or glucose tolerance, are associated with dyslipoproteinemia. This study uses NMR spectroscopy to analyze the lipoprotein subclass patterns of patients with different stages of diabetes and investigates the changes in lipoprotein patterns over time. The study found that the lipoprotein subclass distributions were altered in diabetic patients, but the total concentrations of lipoprotein particles produced by the liver were not significantly changed.
LIPIDS IN HEALTH AND DISEASE
(2023)
Article
Endocrinology & Metabolism
Namam Ali, Soumia El Hamdaoui, Bas J. Schouwenberg, Cees J. Tack, Bastiaan E. de Galan
Summary: This study investigated the current prevalence of impaired awareness of hypoglycaemia (IAH) and its change over time in individuals with type 1 diabetes. The results showed that among individuals using sensor technology, the current prevalence of IAH was 16%, about 50% lower compared to previous years.
Article
Cardiac & Cardiovascular Systems
Procolo Di Bonito, Giuliana Valerio, Maria R. Licenziati, Giuseppina Campana, Emanuele M. del Giudice, Anna Di Sessa, Anita Morandi, Claudio Maffeis, Claudio Chiesa, Lucia Pacifico, Marco G. Baroni, Melania Manco
Summary: The study revealed a significant association between uric acid levels and markers of prediabetes, insulin resistance, and insulin sensitivity in overweight/obese youth. Higher uric acid levels were correlated with elevated markers of impaired glucose metabolism, particularly post-challenge conditions.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2021)
Article
Endocrinology & Metabolism
Yingting Zuo, Xinsheng Han, Xue Tian, Shuohua Chen, Shouling Wu, Anxin Wang
Summary: The study revealed that individuals without traditional ASCVD risk factors are at increased risk of developing CVD with higher levels of abnormal fasting plasma glucose, underlining the importance of prevention strategies targeting elevated FPG levels in addition to other traditional ASCVD risk factors.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Environmental Sciences
Zhijiang Liang, Lina Zhao, Jialing Qiu, Xinhong Zhu, Min Jiang, Guocheng Liu, Qingguo Zhao
Summary: Previous studies have shown a link between maternal exposure to PM2.5 and preterm birth, with a stronger effect observed in pre-pregnancy impaired fasting glucose (IFG) women during the first trimester. The risk of preterm birth, especially early preterm birth, is increased with higher PM2.5 exposure levels in both IFG and normoglycemia women.
ENVIRONMENTAL RESEARCH
(2022)
Article
Public, Environmental & Occupational Health
Feifei Liu, Ke Zhang, Gongbo Chen, Jie He, Mengnan Pan, Feng Zhou, Xiangxiang Wang, Jiahui Tong, Yuming Guo, Shanshan Li, Hao Xiang
Summary: This study found that exposure to PM10, PM2.5, and NO2 was associated with elevated blood sugar levels and increased incidence of diabetes in elderly Chinese populations. With the rising prevalence and incidence of diabetes in China, urgent measures to improve air quality are needed.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Xin Zhang, Yankun Yue, Shaobo Liu, Xiangfeng Cong, Wenjuan Wang, Jianhong Li
Summary: This study investigates the relationship between BMI and the risk of impaired glucose tolerance (IGT) and impaired fasting glucose (IFG) in Chinese adults. The results show that obesity is an important risk factor for IGT and IFG in China, and the risk of IGT increases during the overweight stage.
Article
Health Care Sciences & Services
Pedro M. Magalhaes, Jose E. Teixeira, Joao P. Bragada, Carlos M. Duarte, Jose A. Bragada
Summary: The aims of this study were to evaluate the prevalence of type 2 diabetes (T2D) in a middle-aged north-eastern Portuguese population, analyze the prevalence of impaired fasting glucose (IFG), and assess the risk of T2D in this community-based sample. The study found that the prevalence of T2D in this population was 17.4%, with a higher prevalence in men compared to women. The prevalence of T2D and IFG increased with age, and the risk of developing T2D was associated with sex and age group.
Article
Endocrinology & Metabolism
Caterina Racca, Emma J. Bouman, Cornelis A. J. Van Beers, Mark M. Smits, Daniel H. van Raalte, Erik H. Sern
Summary: This study assessed the prevalence of cardiovascular autonomic neuropathy (CAN) and the association between glucose variability (GV) and cardiovascular autonomic function in patients with type 1 diabetes (T1DM) and impaired awareness of hypoglycaemia (IAH). The results showed that CAN was present in 35% of the participants and participants with CAN had lower hypoglycaemic parameters. After correction for confounders, there was a significant positive association between hypoglycaemic parameters and cardiovascular autonomic function measures.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2022)
Article
Nutrition & Dietetics
Bo-Ying Zang, Li-Xia He, Ling Xue
Summary: Obesity and diabetes are significant health issues, and moderate weight loss is important for reducing the risk of metabolic diseases. Intermittent fasting (IF) is a popular weight loss strategy, but more research is needed, especially regarding its application in obese and type 2 diabetic patients.
Review
Peripheral Vascular Disease
Nicolas Renna, Daniel Piskorz, Diego Stisman, Diego Martinez, Ludmila Lescano, Sergio Vissani, Walter Espeche, Diego Marquez, Roberto Parodi, Diego Naninni, Marcos Baroni, Daniel Llanos, Rocio Martinez, Jessica Barochinner, Gustavo Staffieri, Fernando Lanas, Monica Velasquez, Marcos Marin, Bryan Williams, Irene Ennis
Summary: This document provides a comprehensive review of the scientific evidence on the use of single pill combinations (SPCs) in the treatment of hypertension. It highlights the importance of using multiple drugs to achieve blood pressure goals and the inverse relationship between treatment adherence and the number of drugs taken. The document also discusses the effectiveness and adverse effects of SPCs, their use in special populations, and their impact on hypertensive-mediated organ damage.
JOURNAL OF HUMAN HYPERTENSION
(2023)
Article
Cardiac & Cardiovascular Systems
Sylvia Haas, John A. Camm, Darius Harald, Jan Steffel, Saverio Virdone, Karen Pieper, Marianne Brodmann, Sebastian Schellong, Frank Misselwitz, Gloria Kayani, Ajay K. Kakkar
Summary: There are similarities and dissimilarities in AF management and clinical outcomes between DACH and ORW regions. The increased use of NOACs in DACH is associated with a mismatch in risk-adapted anticoagulation. Suboptimal control of INR is observed in both regions. DACH region has higher rates of cardiovascular death and lower rates of non-haemorrhagic stroke.
CLINICAL RESEARCH IN CARDIOLOGY
(2023)
Article
Clinical Neurology
Andrew Smyth, Martin O'Donnell, Sumathy Rangarajan, Graeme J. Hankey, Shahram Oveisgharan, Michelle Canavan, Clodagh McDermott, Denis Xavier, Hongye Zhang, Albertino Damasceno, Alvaro Avezum, Nana Pogosova, Aytekin Oguz, Danuta Ryglewicz, Helle Klingenberg Iversen, Fernando Lanas, Annika Rosengren, Salim Yusuf, Peter Langhorne
Summary: This study examined the association between alcohol consumption and stroke in a large international population. It found that high and moderate alcohol intake increased the odds of stroke, while low intake was not associated with stroke. However, there were regional variations in the relationship.
Article
Nutrition & Dietetics
Mahshid Dehghan, Andrew Mente, Sumathy Rangarajan, Viswanathan Mohan, Sumathi Swaminathan, Alvaro Avezum, Scott A. Lear, Annika Rosengren, Paul Poirier, Fernando Lanas, Patricio Lopez-Jaramillo, Biju Soman, Chuangshi Wang, Andres Orlandini, Noushin Mohammadifard, Khalid F. AlHabib, Jephat Chifamba, Afzal Hussein Yusufali, Romaina Iqbal, Rasha Khatib, Karen Yeates, Thandi Puoane, Yuksel Altuntas, Homer Uy Co, Sidong Li, Weida Liu, Katarzyna Zatonska, Rita Yusuf, Noorhassim Ismail, Victoria Miller, Salim Yusuf
Summary: This study found that higher intake of ultra-processed foods (UPFs) is associated with increased risk of mortality and cardiovascular disease (CVD) in a diverse multinational cohort. The results showed that a diet high in UPFs is related to higher risk of total mortality, cardiovascular mortality, and non-cardiovascular mortality, but not major CVD events.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2023)
Review
Cardiac & Cardiovascular Systems
Ruvistay Gutierrez-Arias, Jorge Hinojosa-Riadi, Adrian Sandoval-Canio, Hannelore Santana-Garrido, Nicolas Valdovinos-Guerrero, Pamela Seron
Summary: The effectiveness of respiratory muscle training in adult patients with pulmonary hypertension (PH) is uncertain. It is unclear whether respiratory muscle training can improve functional exercise capacity and reduce dyspnea sensation, and whether it has an impact on quality of life. Further well-designed randomized controlled trials are needed to determine the real effect of this intervention.
HEART LUNG AND CIRCULATION
(2023)
Article
Environmental Sciences
Ying Wang, MyLinh Duong, Michael Brauer, Sumathy Rangarajan, Antonio Dans, Fernando Lanas, Patricio Lopez-Jaramillo, Thandi Puoane, Karen Yeates, Jephat Chifamba, Rita Yusuf, Zhiguang Liu, Yang Li, Lap Ah Tse, Deepa Mohan, Rajeev Gupta, Sanjeev Nair, P. V. M. Lakshmi, Romaina Iqbal, Taniya Anto, Salim Yusuf, Perry Hystad
Summary: This study examines the association between household air pollution (HAP) from solid fuel cooking and respiratory health. It finds that using solid fuels is associated with lower lung function and an increased risk of respiratory diseases and mortality. However, switching from solid fuels to clean fuels can improve lung function and decrease the risk of respiratory events.
ENVIRONMENTAL HEALTH PERSPECTIVES
(2023)
Review
Public, Environmental & Occupational Health
Edgar D. Hernandez, Elisa A. Cobo, Lawrence P. Cahalin, Pamela Seron
Summary: This study aimed to determine the effectiveness of structural-level environmental interventions on changes in physical activity (PA) levels in populations. A literature search was conducted to include natural experiments with structural modifications, and the results showed that such interventions can improve PA levels, with the greatest effect observed in parks and active transportation.
INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH
(2023)
Article
Medicine, General & Internal
Ruvistay Gutierrez-Arias, Dawid Pieper, Carole Lunny, Rodrigo Torres-Castro, Raul Aguilera-Eguia, Pamela Seron
Summary: The purpose of this study is to describe the strategies used by authors of overviews focusing on exercise-related interventions to manage the overlap of primary studies. A comprehensive search strategy will be developed, and the information from the included overviews will be extracted. The findings of this study will be presented at scientific conferences and published in peer-reviewed scientific journals related to rehabilitation or research methods.
Article
Cardiac & Cardiovascular Systems
Andrew Mente, Mahshid Dehghan, Sumathy Rangarajan, Martin O'Donnell, Weihong Hu, Gilles Dagenais, Andreas Wielgosz, Scott A. Lear, Li Wei, Rafael Diaz, Alvaro Avezum, Patricio Lopez-Jaramillo, Fernando Lanas, Sumathi Swaminathan, Manmeet Kaur, K. Vijayakumar, Viswanathan Mohan, Rajeev Gupta, Andrzej Szuba, Romaina Iqbal, Rita Yusuf, Noushin Mohammadifard, Rasha Khatib, Nafiza Mat Nasir, Kubilay Karsidag, Annika Rosengren, Afzalhussein Yusufali, Edelweiss Wentzel-Viljoen, Jephat Chifamba, Antonio Dans, Khalid F. Alhabib, Karen Yeates, Koon Teo, Hertzel C. Gerstein, Salim Yusuf
Summary: A healthy diet score based on fruits, vegetables, nuts, legumes, fish, and whole-fat dairy is associated with lower risk of all-cause mortality, cardiovascular disease, myocardial infarction, and stroke in a global population. This score exhibits stronger associations with death or CVD compared to other common diet scores.
EUROPEAN HEART JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Darryl P. Leong, Philip Joseph, John J. Mcmurray, Jean Rouleau, Aldo P. Maggioni, Fernando Lanas, Sanjib K. Sharma, Julio Nunez, Bishav Mohan, Ahmet Celik, Jabir Abdullakutty, Okechukwu S. Ogah, Lisa M. Mielniczuk, Kumar Balasubramanian, Tara Mccready, Alex Grinvalds, Salim Yusuf, G CHF Investigators
Summary: Frailty has incremental prognostic importance in predicting death and HF hospitalization in HF populations, beyond conventional prognostic variables. This relationship is consistent across countries at all income levels.
EUROPEAN HEART JOURNAL
(2023)
Article
Public, Environmental & Occupational Health
Daniela Gomez-Perez, Pamela Seron, Maria Jose Oliveros, Gladys Morales Illanes, Maria Jose Arancibia, Sherry L. Grace
Summary: This study evaluated the usefulness of a booklet as support material for counseling in a hybrid CR program developed for low-resource settings. The results showed that the booklet was easy to understand, contained practical suggestions, and was useful for future questions. Both patients and delivering professionals found the booklet to be helpful in counseling. This resource can be disseminated for use by other Spanish CR programs.
PATIENT EDUCATION AND COUNSELING
(2023)
Review
Medicine, General & Internal
Raul Alberto Aguilera-Eguia, Ruvistay Gutierrez-Arias, Carlos Zaror, Pamela Seron
Summary: This study aims to evaluate the effectiveness of different physical exercise programmes in reducing the volume of lymphoedema, pain intensity, and improving quality of life in breast cancer-related lymphoedema patients. The researchers will collect data by searching databases and assess the overall quality of evidence using the Grading of Recommendations Assessment, Development and Evaluation System. The results will be published in peer-reviewed journals and disseminated in scientific conferences.
Article
Medicine, General & Internal
Ruvistay Gutierrez-Arias, Dawid Pieper, Peter Nydahl, Felipe Gonzalez-Seguel, Yorschua Jalil, Maria-Jose Oliveros, Rodrigo Torres-Castro, Pamela Seron
Summary: This study aims to evaluate the redundancy, methodological and reporting quality, and potential reasons for discordance in systematic reviews (SRs) conducted to determine the effectiveness of early mobilisation in critically ill adult patients. Through searching multiple databases, reviewing literature and assessing the quality of studies, the effectiveness of this intervention will be explored. Findings of this study will be disseminated at conferences and published in a peer-reviewed journal.
Article
Biochemistry & Molecular Biology
Cristian Morales, Raul Arias-Carrasco, Vinicius Maracaja-Coutinho, Pamela Seron, Fernando Lanas, Luis A. Salazar, Nicolas Saavedra
Summary: This study aimed to identify differences in bacterial small RNAs between hypercholesterolemic and normocholesterolemic individuals at the gut level. Most of the small RNAs were of bacterial origin and had a higher number of readings in normocholesterolemic participants. Small RNA ID 2909606 associated with Coprococcus eutactus and small RNA ID 2149569 from the species Blautia wexlerae were upregulated in hypercholesterolemic subjects, and other bacterial and archaeal small RNAs interacting with the LDL receptor were identified.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Geriatrics & Gerontology
Patricio Lopez-Jaramillo, Diego Gomez-Arbelaez, Daniel Martinez-Bello, Marc Evans M. Abat, Khalid F. Alhabib, Alvaro Avezum, Olga Barbarash, Jephat Chifamba, Maria L. Diaz, Sadi Gulec, Noorhassim Ismail, Romaina Iqbal, Roya Kelishadi, Rasha Khatib, Fernando Lanas, Naomi S. Levitt, Yang Li, Viswanathan Mohan, Prem K. Mony, Paul Poirier, Annika Rosengren, Biju Soman, Chuangshi Wang, Yang Wang, Karen Yeates, Rita Yusuf, Afzalhussein Yusufali, Katarzyna Zatonska, Sumathy Rangarajan, Salim Yusuf
Summary: The TyG index is associated with cardiovascular diseases and mortality, especially in Asia. It is significantly related to the risk of cardiovascular diseases, myocardial infarction, stroke, and type 2 diabetes, indicating that insulin resistance plays a promoting role in the development of these diseases.
LANCET HEALTHY LONGEVITY
(2023)