Bortezomib initiates endoplasmic reticulum stress, elicits autophagy and death in Echinococcus granulosus larval stage

Biochemical and molecular characterization of the calcineurin in Echinococcus granulosus larval stages

(2015) María Celeste Nicolao et al.   ACTA TROPICA

Pharmacologic screens reveal metformin that suppresses GRP78-dependent autophagy to enhance the anti-myeloma effect of bortezomib

(2015) S Jagannathan et al.   LEUKEMIA

Molecular identification and characterization of Trichinella spiralis proteasome subunit beta type-7

(2015) Wei Yang et al.   Parasites & Vectors

Molecular chaperone GRP78 enhances aggresome delivery to autophagosomes to promote drug resistance in multiple myeloma

(2015) Mohamed A.Y. Abdel Malek et al.   Oncotarget

Endoplasmic reticulum chaperone GRP78 is involved in autophagy activation induced by ischemic preconditioning in neural cells

(2015) Xiang-Yang Zhang et al.   Molecular Brain

In VitroandIn VivoEffects of Tamoxifen against Larval Stage Echinococcus granulosus

(2014) María Celeste Nicolao et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

(2014) Daniel J. Klionsky et al.   Autophagy

Identification and pharmacological induction of autophagy in the larval stages of Echinococcus granulosus: an active catabolic process in calcareous corpuscles

(2014) Julia A. Loos et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Endoplasmic reticulum stress responses in Leishmania

(2014) Subhankar Dolai et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

It's All in Your Mind: Determining Germ Cell Fate by Neuronal IRE-1 in C. elegans

(2014) Mor Levi-Ferber et al.   PLoS Genetics

Profound Activity of the Anti-cancer Drug Bortezomib against Echinococcus multilocularis Metacestodes Identifies the Proteasome as a Novel Drug Target for Cestodes

(2014) Britta Stadelmann et al.   PLoS Neglected Tropical Diseases

Evolution of the unfolded protein response

(2013) Julie Hollien   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Proteomic characterization of larval and adult developmental stages in Echinococcus granulosus reveals novel insight into host–parasite interactions

(2013) Shu-Jian Cui et al.   Journal of Proteomics

The genomes of four tapeworm species reveal adaptations to parasitism

(2013) Isheng J. Tsai et al.   NATURE

The genome of the hydatid tapeworm Echinococcus granulosus

(2013) Huajun Zheng et al.   NATURE GENETICS

JNK and Macroautophagy Activation by Bortezomib Has a Pro-Survival Effect in Primary Effusion Lymphoma Cells

(2013) Marisa Granato et al.   PLoS One

IRE1: ER stress sensor and cell fate executor

(2013) Yani Chen et al.   TRENDS IN CELL BIOLOGY

The novel combination of sirolimus and bortezomib prevents graft-versus-host disease but maintains the graft-versus-leukemia effect after allogeneic transplantation

(2012) T. Caballero-Velazquez et al.   HAEMATOLOGICA

Understanding the laminated layer of larval Echinococcus I: structure

(2011) Alvaro Díaz et al.   TRENDS IN PARASITOLOGY

Macroautophagy and ERK phosphorylation counteract the anti-proliferative effect of proteasome inhibitor in gastric cancer cells

(2010) William Ka Kei Wu et al.   Autophagy

Bortezomib blocks the catabolic process of autophagy via a cathepsin-dependent mechanism, affects endoplasmic reticulum stress, and induces caspase-dependent cell death in antiestrogen–sensitive and resistant ER+ breast cancer cells

(2010) Sudharsan Periyasamy-Thandavan et al.   Autophagy

Expert consensus for the diagnosis and treatment of cystic and alveolar echinococcosis in humans

(2009) Enrico Brunetti et al.   ACTA TROPICA

Mechanisms of cross-talk between the ubiquitin-proteasome and autophagy-lysosome systems

(2009) Viktor I. Korolchuk et al.   FEBS LETTERS

Identification of functional FKB protein in Echinococcus granulosus: Its involvement in the protoscolicidal action of rapamycin derivates and in calcium homeostasis

(2009) Andrea C. Cumino et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Signalling Pathways in the Unfolded Protein Response: Development from Yeast to Mammals

(2009) K. Mori   JOURNAL OF BIOCHEMISTRY

Fine-Tuning of the Unfolded Protein Response: Assembling the IRE1α Interactome

(2009) Claudio Hetz et al.   MOLECULAR CELL

Trypanocidal activity of the proteasome inhibitor and anti-cancer drug bortezomib

(2009) Dietmar Steverding et al.   Parasites & Vectors

Flubendazole interferes with a wide spectrum of cell homeostatic mechanisms in Echinococcus granulosus protoscoleces

(2009) Andrea C. Cumino et al.   PARASITOLOGY INTERNATIONAL

Structure of the Dual Enzyme Ire1 Reveals the Basis for Catalysis and Regulation in Nonconventional RNA Splicing

(2008) Kenneth P.K. Lee et al.   CELL

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells

(2008) J Li et al.   CELL DEATH AND DIFFERENTIATION

The potential of proteasome inhibitors in cancer therapy

(2008) Jan Sterz et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Role of JNK1-dependent Bcl-2 Phosphorylation in Ceramide-induced Macroautophagy

(2008) Sophie Pattingre et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Echinococcus granulosus calreticulin: Molecular characterization and hydatid cyst localization

(2008) Carolina Cabezón et al.   MOLECULAR IMMUNOLOGY

The pivotal role of c-Jun NH2-terminal kinase-mediated Beclin 1 expression during anticancer agents-induced autophagy in cancer cells

(2008) D-D Li et al.   ONCOGENE