Programmed cell death-1, PD-1, is dysregulated in T cells from children with new onset type 1 diabetes

PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation

(2015) Nikolaos Patsoukis et al.   Nature Communications

The PD-1/PD-Ls pathway and autoimmune diseases

(2014) Suya Dai et al.   CELLULAR IMMUNOLOGY

Renegade homeostatic cytokine responses in T1D: Drivers of regulatory/effector T cell imbalance

(2014) Shipra Gupta et al.   CLINICAL IMMUNOLOGY

Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis

(2013) Chih-Hao Chang et al.   CELL

Altered Immune Regulation in Type 1 Diabetes

(2013) András Zóka et al.   Clinical & Developmental Immunology

PD-1, but Not PD-L1, Expressed by Islet-Reactive CD4 + T Cells Suppresses Infiltration of the Pancreas During Type 1 Diabetes

(2013) Kristen E. Pauken et al.   DIABETES

B7 family checkpoint regulators in immune regulation and disease

(2013) Sabrina Ceeraz et al.   TRENDS IN IMMUNOLOGY

Changes in Treatment Adherence and Glycemic Control During the Transition to Adolescence in Type 1 Diabetes

(2012) J. R. Rausch et al.   DIABETES CARE

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

Metagenomics and Personalized Medicine

(2011) Herbert W. Virgin et al.   CELL

Deficiency in B7-H1 (PD-L1)/PD-1 Coinhibition Triggers Pancreatic β-Cell Destruction by Insulin-Specific, Murine CD8 T-Cells

(2010) Tarvo Rajasalu et al.   DIABETES

Congenic Mesenchymal Stem Cell Therapy Reverses Hyperglycemia in Experimental Type 1 Diabetes

(2010) M. Jurewicz et al.   DIABETES

Targeting the CXCR4-CXCL12 Axis Mobilizes Autologous Hematopoietic Stem Cells and Prolongs Islet Allograft Survival via Programmed Death Ligand 1

(2010) P. Fiorina et al.   JOURNAL OF IMMUNOLOGY

Immunomodulatory Function of Bone Marrow-Derived Mesenchymal Stem Cells in Experimental Autoimmune Type 1 Diabetes

(2009) P. Fiorina et al.   JOURNAL OF IMMUNOLOGY

Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR–induced stop signal

(2009) Brian T Fife et al.   NATURE IMMUNOLOGY