Human leucocyte antigen (HLA-DR) gene expression is reduced in sepsis and correlates with impaired TNFα response: A diagnostic tool for immunosuppression?

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

(2016) Mervyn Singer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Immune Cell Phenotype and Function in Sepsis

(2016) Thomas Rimmelé et al.   SHOCK

Stimulated Whole Blood Cytokine Release as a Biomarker of Immunosuppression in the Critically Ill

(2016) Elisabetta Segre et al.   SHOCK

Quantitative Real-Time Polymerase Chain Reaction Measurement of HLA-DRA Gene Expression in Whole Blood Is Highly Reproducible and Shows Changes That Reflect Dynamic Shifts in Monocyte Surface HLA-DR Expression during the Course of Sepsis

(2016) Sara Cajander et al.   PLoS One

Human Monocytes Undergo Functional Re-programming during Sepsis Mediated by Hypoxia-Inducible Factor-1α

(2015) Irina N. Shalova et al.   IMMUNITY

Sepsis: Current Dogma and New Perspectives

(2014) Clifford S. Deutschman et al.   IMMUNITY

Immunosuppression in sepsis: a novel understanding of the disorder and a new therapeutic approach

(2013) Richard S Hotchkiss et al.   LANCET INFECTIOUS DISEASES

Reversal of Immunoparalysis in HumansIn Vivo

(2012) Jenneke Leentjens et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Granulocyte–Macrophage Colony-stimulating Factor to Reverse Sepsis-associated Immunosuppression

(2009) Christian Meisel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Monocytic HLA-DR expression in intensive care patients: Interest for prognosis and secondary infection prediction*

(2009) Anne-Claire Lukaszewicz et al.   CRITICAL CARE MEDICINE

Gene-expression profiling of peripheral blood mononuclear cells in sepsis*

(2009) Benjamin M. P. Tang et al.   CRITICAL CARE MEDICINE