The cryptic plasmid is more important for Chlamydia muridarum to colonize the mouse gastrointestinal tract than to infect the genital tract

Chlamydial Plasmid-Dependent Pathogenicity

(2017) Guangming Zhong   TRENDS IN MICROBIOLOGY

Intravenous Inoculation with Chlamydia muridarum Leads to a Long-Lasting Infection Restricted to the Gastrointestinal Tract

(2016) Jin Dai et al.   INFECTION AND IMMUNITY

The p47phox deficiency significantly attenuates the pathogenicity of Chlamydia muridarum in the mouse oviduct but not uterine tissues

(2016) Jin Dai et al.   MICROBES AND INFECTION

The Chlamydia muridarum Organisms Fail to Auto-Inoculate the Mouse Genital Tract after Colonization in the Gastrointestinal Tract for 70 days

(2016) Luying Wang et al.   PLoS One

Is it time to switch to doxycycline from azithromycin for treating genital chlamydial infections in women? Modelling the impact of autoinoculation from the gastrointestinal tract to the genital tract

(2015) Andrew P Craig et al.   BMC INFECTIOUS DISEASES

The contribution of Chlamydia -specific CD8+ T cells to upper genital tract pathology

(2015) Kelly R Vlcek et al.   IMMUNOLOGY AND CELL BIOLOGY

Comparable Genital Tract Infection, Pathology, and Immunity in Rhesus Macaques Inoculated with Wild-Type or Plasmid-Deficient Chlamydia trachomatis Serovar D

(2015) Yanyan Qu et al.   INFECTION AND IMMUNITY

The Chromosome-Encoded Hypothetical Protein TC0668 Is an Upper Genital Tract Pathogenicity Factor of Chlamydia muridarum

(2015) Turner Allen Conrad et al.   INFECTION AND IMMUNITY

In VitroPassage Selects for Chlamydia muridarum with Enhanced Infectivity in Cultured Cells but Attenuated Pathogenicity in Mouse Upper Genital Tract

(2015) Chaoqun Chen et al.   INFECTION AND IMMUNITY

In VivoandEx VivoImaging Reveals a Long-Lasting Chlamydial Infection in the Mouse Gastrointestinal Tract following Genital Tract Inoculation

(2015) Qi Zhang et al.   INFECTION AND IMMUNITY

Intrauterine Infection with Plasmid-Free Chlamydia muridarum Reveals a Critical Role of the Plasmid in Chlamydial Ascension and Establishes a Model for Evaluating Plasmid-Independent Pathogenicity

(2015) Jianlin Chen et al.   INFECTION AND IMMUNITY

Rectal chlamydia infection in women at high risk of chlamydia attending Canberra Sexual Health Centre

(2015) Kate Musil et al.   INTERNATIONAL JOURNAL OF STD & AIDS

Plasmid-Encoded Pgp5 Is a Significant Contributor to Chlamydia muridarum Induction of Hydrosalpinx

(2015) Yumeng Huang et al.   PLoS One

Evidence for Increased Chlamydia Case Finding After the Introduction of Rectal Screening Among Women Attending 2 Canadian Sexually Transmitted Infection Clinics

(2014) J. Gratrix et al.   CLINICAL INFECTIOUS DISEASES

An atypical CD8 T-cell response toChlamydia muridarumgenital tract infections includes T cells that produce interleukin-13

(2014) Raymond M. Johnson et al.   IMMUNOLOGY

Hidden in Plain Sight: Chlamydial Gastrointestinal Infection and Its Relevance to Persistence in Human Genital Infection

(2014) Roger G. Rank et al.   INFECTION AND IMMUNITY

Lack of Long-Lasting Hydrosalpinx in A/J Mice Correlates with Rapid but Transient Chlamydial Ascension and Neutrophil Recruitment in the Oviduct following Intravaginal Inoculation with Chlamydia muridarum

(2014) Hongbo Zhang et al.   INFECTION AND IMMUNITY

Plasmid CDS5 Influences Infectivity and Virulence in a Mouse Model of Chlamydia trachomatis Urogenital Infection

(2014) K. H. Ramsey et al.   INFECTION AND IMMUNITY

Complement Factor C5 but Not C3 Contributes Significantly to Hydrosalpinx Development in Mice Infected with Chlamydia muridarum

(2014) Zhangsheng Yang et al.   INFECTION AND IMMUNITY

Plasmid-Encoded Pgp3 Is a Major Virulence Factor for Chlamydia muridarum To Induce Hydrosalpinx in Mice

(2014) Yuanjun Liu et al.   INFECTION AND IMMUNITY

Chlamydial Induction of Hydrosalpinx in 11 Strains of Mice Reveals Multiple Host Mechanisms for Preventing Upper Genital Tract Pathology

(2014) Jianlin Chen et al.   PLoS One

Bioluminescence Imaging of Chlamydia muridarum Ascending Infection in Mice

(2014) Jessica Campbell et al.   PLoS One

Prevalence and Characteristics of Rectal Chlamydia and Gonorrhea Cases Among Men Who Have Sex With Men After the Introduction of Nucleic Acid Amplification Test Screening at 2 Canadian Sexually Transmitted Infection Clinics

(2014) Jennifer Gratrix et al.   SEXUALLY TRANSMITTED DISEASES

Cross-Sectional Study of Genital, Rectal, and Pharyngeal Chlamydia and Gonorrhea in Women in Rural South Africa

(2014) Remco P.H. Peters et al.   SEXUALLY TRANSMITTED DISEASES

Human enteroendocrine cell responses to infection with Chlamydia trachomatis: a microarray study

(2014) Aldona Dlugosz et al.   Gut Pathogens

Differential Susceptibilities to Azithromycin Treatment of Chlamydial Infection in the Gastrointestinal Tract and Cervix

(2013) Laxmi Yeruva et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Reduced Live Organism Recovery and Lack of Hydrosalpinx in Mice Infected with Plasmid-Free Chlamydia muridarum

(2013) Lei Lei et al.   INFECTION AND IMMUNITY

Contribution of Interleukin-12 p35 (IL-12p35) and IL-12p40 to Protective Immunity and Pathology in Mice Infected with Chlamydia muridarum

(2013) Lili Chen et al.   INFECTION AND IMMUNITY

Transformation of Chlamydia muridarum Reveals a Role for Pgp5 in Suppression of Plasmid-Dependent Gene Expression

(2013) Y. Liu et al.   JOURNAL OF BACTERIOLOGY

Characterization of Chlamydia trachomatis Plasmid-Encoded Open Reading Frames

(2013) S. Gong et al.   JOURNAL OF BACTERIOLOGY

Induction of protective immunity against Chlamydia muridarum intravaginal infection with the chlamydial immunodominant antigen macrophage infectivity potentiator

(2013) Chunxue Lu et al.   MICROBES AND INFECTION

Oviduct Infection and Hydrosalpinx in DBA1/j Mice Is Induced by Intracervical but Not Intravaginal Inoculation with Chlamydia muridarum

(2013) Lingli Tang et al.   PLoS One

B Cells Enhance Antigen-Specific CD4 T Cell Priming and Prevent Bacteria Dissemination following Chlamydia muridarum Genital Tract Infection

(2013) Lin-Xi Li et al.   PLoS Pathogens

Chlamydial infection of the gastrointestinal tract: a reservoir for persistent infection

(2013) Laxmi Yeruva et al.   Pathogens and Disease

Plasmid-mediated transformation tropism of chlamydial biovars

(2013) Lihua Song et al.   Pathogens and Disease

OT-1 mice display minimal upper genital tract pathology following primary intravaginalChlamydia muridaruminfection

(2013) Srikanth Manam et al.   Pathogens and Disease

Chlamydia trachomatis Antigens Recognized in Women With Tubal Factor Infertility, Normal Fertility, and Acute Infection

(2012) Nicole M. Budrys et al.   OBSTETRICS AND GYNECOLOGY

Genome-wide identification of Chlamydia trachomatis antigens associated with tubal factor infertility

(2011) Allison K. Rodgers et al.   FERTILITY AND STERILITY

Tumor Necrosis Factor Alpha Production from CD8+T Cells Mediates Oviduct Pathological Sequelae following Primary Genital Chlamydia muridarum Infection

(2011) Ashlesh K. Murthy et al.   INFECTION AND IMMUNITY

Association of tubal factor infertility with elevated antibodies to Chlamydia trachomatis caseinolytic protease P

(2010) Allison K. Rodgers et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Characterization of Pgp3, a Chlamydia trachomatis Plasmid-Encoded Immunodominant Antigen

(2010) D. Chen et al.   JOURNAL OF BACTERIOLOGY

Mice Deficient in MyD88 Develop a Th2-Dominant Response and Severe Pathology in the Upper Genital Tract following Chlamydia muridarum Infection

(2010) Lili Chen et al.   JOURNAL OF IMMUNOLOGY

Chlamydia vaccine candidates and tools for chlamydial antigen discovery

(2009) Daniel D Rockey et al.   Expert Review of Vaccines

Distinct Roles of CD28- and CD40 Ligand-Mediated Costimulation in the Development of Protective Immunity and Pathology during Chlamydia muridarum Urogenital Infection in Mice

(2009) L. Chen et al.   INFECTION AND IMMUNITY

A MyD88-Dependent Early IL-17 Production Protects Mice against Airway Infection with the Obligate Intracellular Pathogen Chlamydia muridarum

(2009) X. Zhang et al.   JOURNAL OF IMMUNOLOGY

The Chlamydial Plasmid-Encoded Protein pgp3 Is Secreted into the Cytosol of Chlamydia-Infected Cells

(2008) Z. Li et al.   INFECTION AND IMMUNITY