High-resolution respirometry of fine-needle muscle biopsies in pre-manifest Huntington’s disease expansion mutation carriers shows normal mitochondrial respiratory function

Selective striatal mtDNA depletion in end-stage Huntington's disease R6/2 mice

(2015) Tanja Hering et al.   EXPERIMENTAL NEUROLOGY

Treating the whole body in Huntington's disease

(2015) Jeffrey B Carroll et al.   LANCET NEUROLOGY

Differences in mitochondrial function in homogenated samples from healthy and epileptic specific brain tissues revealed by high-resolution respirometry

(2015) Johannes Burtscher et al.   MITOCHONDRION

Comparative biochemical characterization of the monoacylglycerol lipase inhibitor KML29 in brain, spinal cord, liver, spleen, fat and muscle tissue

(2015) Noemi Pasquarelli et al.   NEUROPHARMACOLOGY

Exercise training normalizes mitochondrial respiratory capacity within the striatum of the R6/1 model of Huntington’s disease

(2015) E.A.F. Herbst et al.   NEUROSCIENCE

Physiological and Immune-Biological Characterization of a Long-Term Murine Model of Blunt Chest Trauma

(2015) Sebastian Hafner et al.   SHOCK

A single nucleotide polymorphism in the coding region of PGC-1α is a male-specific modifier of Huntington disease age-at-onset in a large European cohort

(2014) Patrick Weydt et al.   BMC Neurology

Progressive hepatic mitochondrial dysfunction in premanifest Huntington's disease

(2014) Rainer Hoffmann et al.   MOVEMENT DISORDERS

Metabolism in HD: Still a relevant mechanism?

(2014) Wenzhen Duan et al.   MOVEMENT DISORDERS

Dysfunction of the CNS-Heart Axis in Mouse Models of Huntington's Disease

(2014) Michal Mielcarek et al.   PLoS Genetics

Skeletal muscle pathology in Huntington's disease

(2014) Daniel Zielonka et al.   Frontiers in Physiology

The best approach: Homogenization or manual permeabilization of human skeletal muscle fibers for respirometry?

(2013) Steen Larsen et al.   ANALYTICAL BIOCHEMISTRY

Fast-Twitch Glycolytic Skeletal Muscle Is Predisposed to Age-Induced Impairments in Mitochondrial Function

(2013) R. A. Jacobs et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Mitochondrial respiratory chain complex activity and bioenergetic alterations in human platelets derived from pre-symptomatic and symptomatic Huntington's disease carriers

(2013) Ana C. Silva et al.   MITOCHONDRION

Hepatic mitochondrial dysfunction in manifest and premanifest Huntington disease

(2013) S. H. Stuwe et al.   NEUROLOGY

A Broad Phenotypic Screen Identifies Novel Phenotypes Driven by a Single Mutant Allele in Huntington’s Disease CAG Knock-In Mice

(2013) Sabine M. Hölter et al.   PLoS One

Skeletal muscle aging and the mitochondrion

(2013) Matthew L. Johnson et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

UCP2 inhibition triggers ROS-dependent nuclear translocation of GAPDH and autophagic cell death in pancreatic adenocarcinoma cells

(2012) Ilaria Dando et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Shaping the role of mitochondria in the pathogenesis of Huntington's disease

(2012) Veronica Costa et al.   EMBO JOURNAL

The C57Bl/6 mouse serves as a suitable model of human skeletal muscle mitochondrial function

(2012) Robert A. Jacobs et al.   EXPERIMENTAL PHYSIOLOGY

Biomarkers of mitochondrial content in skeletal muscle of healthy young human subjects

(2012) Steen Larsen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Assessment of cortical and striatal involvement in 523 Huntington disease brains

(2012) T. C. Hadzi et al.   NEUROLOGY

The Striatum Is Highly Susceptible to Mitochondrial Oxidative Phosphorylation Dysfunctions

(2011) A. M. Pickrell et al.   JOURNAL OF NEUROSCIENCE

Mitochondrial functional impairment with aging is exaggerated in isolated mitochondria compared to permeabilized myofibers

(2010) Martin Picard et al.   AGING CELL

Beyond the brain: widespread pathology in Huntington's disease

(2009) Jorien MM van der Burg et al.   LANCET NEUROLOGY

Dietary intake in adults at risk for Huntington disease: Analysis of PHAROS Research Participants

(2009) K. Marder et al.   NEUROLOGY

Excitotoxic Neuronal Death and the Pathogenesis of Huntington's Disease

(2008) Ana María Estrada Sánchez et al.   ARCHIVES OF MEDICAL RESEARCH

Weight loss in Huntington disease increases with higher CAG repeat number

(2008) N. A. Aziz et al.   NEUROLOGY