Generation and characterization of an antagonistic monoclonal antibody against an extracellular domain of mouse DP2 (CRTH2/GPR44) receptors for prostaglandin D2

Role of prostaglandin D2and CRTH2 blockade in early- and late-phase nasal responses

(2014) Y. Shiraishi et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Modulation of Circadian Glucocorticoid Oscillation via Adrenal Opioid-CXCR7 Signaling Alters Emotional Behavior

(2013) Yuichi Ikeda et al.   CELL

Advances in adult asthma diagnosis and treatment in 2013

(2013) Andrea J. Apter   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Establishment of monoclonal antibodies against the extracellular domain that block binding of NMO-IgG to AQP4

(2013) Kaori Miyazaki et al.   JOURNAL OF NEUROIMMUNOLOGY

Molecular signatures of G-protein-coupled receptors

(2013) A. J. Venkatakrishnan et al.   NATURE

PGD2-CRTH2 Pathway Promotes Tubulointerstitial Fibrosis

(2012) H. Ito et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Marketed therapeutic antibodies compendium

(2012) Janice M. Reichert   mAbs

A Pharmacological Primer of Biased Agonism

(2012) Bradley T. Andresen   Endocrine Metabolic & Immune Disorders-Drug Targets

Overcoming barriers to membrane protein structure determination

(2011) Roslyn M Bill et al.   NATURE BIOTECHNOLOGY

Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines: 2010 Revision

(2010) Jan L. Brożek et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Therapeutic antibodies directed at G protein-coupled receptors

(2010) Catherine J. Hutchings et al.   mAbs

Clinical studies of the DP1 antagonist laropiprant in asthma and allergic rhinitis

(2009) George Philip et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Prostaglandin D2 Receptors DP and CRTH2 in the Pathogenesis of Asthma

(2008) Masafumi Arima et al.   CURRENT MOLECULAR MEDICINE

Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders

(2008) P. Jeffrey Conn et al.   NATURE REVIEWS DRUG DISCOVERY