Synthesis and bioevaluation of N,4-diaryl-1,3-thiazole-2-amines as tubulin inhibitors with potent antiproliferative activity

Recent developments of 2-aminothiazoles in medicinal chemistry

(2016) Debasis Das et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Novel Natural Product- and Privileged Scaffold-Based Tubulin Inhibitors Targeting the Colchicine Binding Site

(2016) Mengqi Dong et al.   MOLECULES

Microwave-assisted synthesis, molecular docking and antiproliferative activity of (3/5-aryl-1,2,4-oxadiazole-5/3-yl)(3,4,5-trimethoxyphenyl)methanone oxime derivatives

(2015) Qi Guan et al.   MedChemComm

Synthesis and Biological Evaluation of 3-Alkyl-1,5-Diaryl-1H-Pyrazoles as Rigid Analogues of Combretastatin A-4 with Potent Antiproliferative Activity

(2015) Qile Xu et al.   PLoS One

Synthesis and biological evaluation of novel 3,4-diaryl-1,2,5-selenadiazol analogues of combretastatin A-4

(2014) Qi Guan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

New Pyrrole Derivatives with Potent Tubulin Polymerization Inhibiting Activity As Anticancer Agents Including Hedgehog-Dependent Cancer

(2014) Giuseppe La Regina et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery of 4-Aryl-2-benzoyl-imidazoles as Tubulin Polymerization Inhibitor with Potent Antiproliferative Properties

(2013) Min Xiao et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological evaluation of N-alkyl-N-(4-methoxyphenyl)pyridin-2-amines as a new class of tubulin polymerization inhibitors

(2012) Xiao-Feng Wang et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Molecular cytogenetic evaluation of the mechanism of genotoxic potential of amsacrine and nocodazole in mouse bone marrow cells

(2011) Sabry M. Attia   JOURNAL OF APPLIED TOXICOLOGY

Discovery of Novel 2-Aryl-4-benzoyl-imidazoles Targeting the Colchicines Binding Site in Tubulin As Potential Anticancer Agents

(2010) Jianjun Chen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Microtubule-binding agents: a dynamic field of cancer therapeutics

(2010) Charles Dumontet et al.   NATURE REVIEWS DRUG DISCOVERY

From signaling pathways to microtubule dynamics: the key players

(2009) Sandrine Etienne-Manneville   CURRENT OPINION IN CELL BIOLOGY

Discovery of 4-Substituted Methoxybenzoyl-aryl-thiazole as Novel Anticancer Agents: Synthesis, Biological Evaluation, and Structure−Activity Relationships

(2009) Yan Lu et al.   JOURNAL OF MEDICINAL CHEMISTRY

A Fully Diarylmethylene-Bridged Triphenylamine Derivative as Novel Host for Highly Efficient Green Phosphorescent OLEDs

(2009) Zuoquan Jiang et al.   ORGANIC LETTERS

New tubulin targeting agents currently in clinical development

(2008) Robert O Carlson   EXPERT OPINION ON INVESTIGATIONAL DRUGS